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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：713/291  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Global characterization of dose-dependent effects of cadmium in clam Ruditapes philippinarum 期刊论文
ENVIRONMENTAL POLLUTION, 2021, 卷号: 273, 页码: 9
作者:  Zhan, Junfei;  Wang, Shuang;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(1425Kb)  |  收藏  |  浏览/下载：569/217  |  提交时间：2021/05/22
Benchmark dose  Cadmium  Dose-dependent effects  Ruditapes philippinarum  Transcriptomics  
Toxicological effects of As (V) in juvenile rockfish Sebastes schlegelii by a combined metabolomic and proteomic approach 期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: 255, 期号: 2, 页码: 113333
作者:  Xu, LL;  Lu, Z;  Ji, CL;  Cong, M;  Li, F;  Shan, XJ;  Wu, HF
浏览  |  Adobe PDF(1885Kb)  |  收藏  |  浏览/下载：555/290  |  提交时间：2020/07/08
Arsenic  Toxicological effect  Juvenile rockfish  Proteomics  Metabolomics  
Differential biological effects in two pedigrees of clam Ruditapes philippinarum exposed to cadmium using iTRAQ-based proteomics 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2019, 卷号: 65, 页码: 66-72
作者:  Lu, Zhen;  Wang, Shuang;  Shan, Xiujuan;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(875Kb)  |  收藏  |  浏览/下载：728/468  |  提交时间：2020/07/08
Ruditapes philippinarum  Pedigrees  Cadmium  Proteomic profiling  
The role of GST omega in metabolism and detoxification of arsenic in clam Ruditapes philippinarum 期刊论文
AQUATIC TOXICOLOGY, 2018, 卷号: 204, 页码: 9-18
作者:  Chen, Lizhu;  Wu, Huifeng;  Zhao, Jianmin;  Zhang, Wei;  Zhang, Li;  Sun, Shan;  Yang, Dinglong;  Cheng, Bo;  Wang, Qing
浏览  |  Adobe PDF(1921Kb)  |  收藏  |  浏览/下载：464/279  |  提交时间：2020/07/08
Arsenic  Bioaccumulation  Metabolism  Subcellular distribution  Glutathione S-transferase omega  
Digital gene expression analysis in the gills of Ruditapes philippinarum exposed to short- and long-term exposures of ammonia nitrogen 期刊论文
AQUATIC TOXICOLOGY, 2018, 卷号: 194, 页码: 121-131
作者:  Cong, Ming;  Wu, Huifeng;  Cao, Tengfei;  Lv, Jiasen;  Wang, Qing;  Ji, Chenglong;  Li, Chenghua;  Zhao, Jianmin
浏览  |  Adobe PDF(938Kb)  |  收藏  |  浏览/下载：861/533  |  提交时间：2020/07/08
Ruditapes philippinarum  Digital gene expression  Transcriptome  Ammonia nitrogen  Toxicity  
Differential metabolic responses in three life stages of mussels Mytilus galloprovincialis exposed to cadmium 期刊论文
ECOTOXICOLOGY, 2017, 卷号: 26, 期号: 1, 页码: 74-80
作者:  Wu, Huifeng;  Xu, Lanlan;  Yu, Deliang;  Ji, Chenglong;  Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(963Kb)  |  收藏  |  浏览/下载：720/348  |  提交时间：2017/03/17
Mytilus Galloprovincialis  Cadmium  Toxicological Effects  Nmr  Metabolomics  
Homologous cloning, characterization and expression of a new halophyte phytochelatin synthase gene in Suaeda salsa 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2016, 卷号: 34, 期号: 5, 页码: 1034-1043
作者:  Cong, M;  Zhao, JM;  Lu, JS;  Ren, ZM;  Wu, HF;  Wu, HF (reprint author), Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(435Kb)  |  收藏  |  浏览/下载：671/308  |  提交时间：2016/10/08
Suaeda Salsa  Halophyte  Phytochelatin Synthase (Pcs)  Homologous Cloning  Heavy Metal  Tissue Distribution  
Glutathione S-transferase (GST) gene expression profiles in two marine bivalves exposed to BDE-47 and their potential molecular mechanisms 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2015, 卷号: 33, 期号: 3, 页码: 705-713
作者:  Li Fei;  Wu Huifeng;  Wang Qing;  Li Xuehua;  Zhao Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(580Kb)  |  收藏  |  浏览/下载：851/287  |  提交时间：2015/07/31
Glutathione S-transferase (Gst)  Venerupis Philippinarum  Mytilus Galloprovincialis  Molecular Docking  2  Biomarker  2 '  4  4 '-tetrabromodiphenyl Ether (Bde-47)  
Combined metabolome and proteome analysis of the mantle tissue from Pacific oyster Crassostrea gigas exposed to elevated pCO(2) 期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS, 2015, 卷号: 13, 页码: 16-23
作者:  Wei, Lei;  Wang, Qing;  Ning, Xuanxuan;  Mu, Changkao;  Wang, Chunlin;  Cao, Ruiwen;  Wu, Huifeng;  Cong, Ming;  Li, Fei;  Ji, Chenglong;  Zhao, Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
浏览  |  Adobe PDF(588Kb)  |  收藏  |  浏览/下载：965/424  |  提交时间：2015/07/31
Ocean Acidification  Proteomics  Metabolomics  Crassostrea Gigas