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基于有害结局路径网络的有机磷酸酯毒性筛查及机制研究 学位论文
工学博士: 中国科学院烟台海岸带研究所, 2023
作者:  王晓晴
Adobe PDF(21053Kb)  |  收藏  |  浏览/下载:239/4  |  提交时间:2023/06/28
新污染物  有机磷酸酯  有害结局路径网络  计算毒理学  风险预测与评估  
Critical target identification and human health risk ranking of metal ions based on mechanism-driven modeling 期刊论文
CHEMOSPHERE, 2022, 卷号: 301, 页码: 9
作者:  Wang, Xiaoqing;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng;  Li, Fei
收藏  |  浏览/下载:245/0  |  提交时间:2022/07/26
Metal ions  p53  QSAR  Genetic toxicity  Human health risk  
Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载:699/289  |  提交时间:2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Methods, Mechanisms and Typical Bio-Indicators of Engineered Nanoparticle Ecotoxicology: An Overview 期刊论文
CLEAN-SOIL AIR WATER, 2014, 卷号: 42, 期号: 4, 页码: 377-385
作者:  Zhuang, Wen;  Gao, Xuelu;  Gao, XL (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Zone Environm Proc & Ecol Remedia, 17 Chunhui Rd, Yantai 264003, Shandong, Peoples R China. xlgao@yic.ac.cn
浏览  |  Adobe PDF(199Kb)  |  收藏  |  浏览/下载:802/374  |  提交时间:2015/07/31
Aquatic Systems  Bio-indicators  Ecotoxicology  Nanoparticles  
Towards a System Level Understanding of Non-Model Organisms Sampled from the Environment: A Network Biology Approach 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2011, 卷号: 7, 期号: 8, 页码: e1002126
作者:  Williams, Tim D.;  Turan, Nil;  Diab, Amer M.;  Wu, Huifeng;  Mackenzie, Carolynn;  Bartie, Katie L.;  Hrydziuszko, Olga;  Lyons, Brett P.;  Stentiford, Grant D.;  Herbert, John M.;  Abraham, Joseph K.;  Katsiadaki, Ioanna;  Leaver, Michael J.;  Taggart, John B.;  George, Stephen G.;  Viant, Mark R.;  Chipman, Kevin J.;  Falciani, Francesco
浏览  |  Adobe PDF(1348Kb)  |  收藏  |  浏览/下载:1066/229  |  提交时间:2011/11/11
Flounder Platichthys-flesus  Histopathological Biomarkers  Pleuronectes-platessa  Endocrine Disruption  Gene-expression  Liver Fibrosis  Marine Fish  Receptor  Microarray  Proteasome