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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：730/293  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：399/53  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
Toxicological effects of graphene on mussel Mytilus galloprovincialis hemocytes after individual and combined exposure with triphenyl phosphate 期刊论文
MARINE POLLUTION BULLETIN, 2020, 卷号: 151, 页码: 110838
作者:  Meng, Xiangjing;  Li, Fei;  Wang, Xiaoqing;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(2503Kb)  |  收藏  |  浏览/下载：695/298  |  提交时间：2020/07/08
ORGANOPHOSPHATE FLAME RETARDANTS  IN-VITRO  PRISTINE GRAPHENE  OXIDATIVE STRESS  MARINE MUSSEL  CAGED MUSSELS  OXIDE  TOXICITY  NANOPARTICLES  NANOMATERIALS  
典型溴系阻燃剂四溴双酚A和十溴二苯乙烷的污染现状及毒理学研究进展 期刊论文
生态毒理学报, 2020, 卷号: 15, 期号: 6, 页码: 24-42
作者:  王爽;  路珍;  李斐;  丛明;  吉成龙;  吴惠丰
浏览  |  Adobe PDF(646Kb)  |  收藏  |  浏览/下载：667/257  |  提交时间：2021/12/01
四溴双酚A  十溴二苯乙烷  毒性效应  污染现状  
Combinatorial immune and stress response, cytoskeleton and signal transduction effects of graphene and triphenyl phosphate (TPP) in mussel Mytilus galloprovincialis 期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2019, 卷号: 378, 页码: UNSP 120778
作者:  Meng, XJ;  Li, F;  Wang, XQ;  Liu, JL;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(1686Kb)  |  收藏  |  浏览/下载：603/314  |  提交时间：2020/07/08
Joint effects  Graphene  Triphenyl phosphate (TPP)  Toxicity  Mussel  
典型有机磷酸酯阻燃剂有害结局路径(AOP)的机制探索 期刊论文
海岸科学, 2019, 卷号: 6, 期号: 1, 页码: 16-21
作者:  王晓晴;  李斐;  吉成龙;  吴惠丰
Adobe PDF(509Kb)  |  收藏  |  浏览/下载：312/63  |  提交时间：2021/11/11
有机磷酸酯阻燃剂(OPFRs)  毒理效应  计算毒理学  有害结局路径(AOP)  
溴系阻燃剂毒理效应的计算模拟预测与环境风险评估进展 期刊论文
生态毒理学报, 2019, 卷号: 14, 期号: 4, 页码: 2-13
作者:  李斐;  王晓晴;  刘佳琳;  孟祥敬;  吉成龙;  吴惠丰
浏览  |  Adobe PDF(784Kb)  |  收藏  |  浏览/下载：695/329  |  提交时间：2020/07/08
溴系阻燃剂  毒理效应  计算毒理学  风险评估  Brominated Flame Retardants (Bfrs)  Toxicological Effect  Computational Toxicology  Risk Assessment  
Graphene quantum dots in alveolar macrophage: uptake-exocytosis, accumulation in nuclei, nuclear responses and DNA cleavage 期刊论文
PARTICLE AND FIBRE TOXICOLOGY, 2018, 卷号: 15, 页码: 45
作者:  Xu, Lina;  Dai, Yanhui;  Wang, Zhenyu;  Zhao, Jian;  Li, Fei;  White, Jason C.;  Xing, Baoshan
浏览  |  Adobe PDF(7464Kb)  |  收藏  |  浏览/下载：478/131  |  提交时间：2020/07/08
Aminated graphene quantum dots  Macrophages  Endocytosis  Nuclear accumulation  DNA cleavage  Molecular docking  
An integrated proteomic and metabolomic study on the gender-specific responses of mussels Mytilus galloprovincialis to tetrabromobisphenol A (TBBPA) 期刊论文
CHEMOSPHERE, 2016, 卷号: 144, 页码: 527-539
作者:  Ji, CL;  Li, F;  Wang, Q;  Zhao, JM;  Sun, ZD;  Wu, HF;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Environm Proc, Key Lab Coastal Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(2260Kb)  |  收藏  |  浏览/下载：1026/313  |  提交时间：2016/04/24
Gender-specific  Mytilus Galloprovincialis  Proteomics  Metabolomics  Tetrabromobisphenol a  
A defensin from clam Venerupis philippinarum: Molecular characterization, localization, antibacterial activity, and mechanism of action 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2015, 卷号: 51, 期号: 1, 页码: 29-38
作者:  Zhang, LB;  Yang, DL;  Wang, Q;  Yuan, ZY;  Wu, HF;  Pei, D;  Cong, M;  Li, F;  Ji, CL;  Zhao, JM;  Wu, HF (reprint author), YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
浏览  |  Adobe PDF(3713Kb)  |  收藏  |  浏览/下载：545/178  |  提交时间：2016/04/24
Venerupis Philippinarum  Defensin  Molecular Characterization  Tissue Distribution  Antimicrobial Activity  Membrane Lesions