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Abnormality of mussel in the early developmental stages induced by graphene and triphenyl phosphate: In silico toxicogenomic data-mining, in vivo, and toxicity pathway-oriented approach 期刊论文
AQUATIC TOXICOLOGY, 2023, 卷号: 263, 页码: 11
Authors:  Wang, Xiaoqing;  Li, Fei;  Meng, Xiangjing;  Xia, Chunlei;  Ji, Chenglong;  Wu, Huifeng
Favorite  |  View/Download：11/0  |  Submit date：2023/11/15
Plastic additives  Graphene-based nanomaterials  Toxicogenomic data mining  Combined hazards  Developmental abnormality  
基于有害结局路径网络的有机磷酸酯毒性筛查及机制研究 学位论文
工学博士: 中国科学院烟台海岸带研究所, 2023
Authors:  王晓晴
Adobe PDF(21053Kb)  |  Favorite  |  View/Download：86/4  |  Submit date：2023/06/28
新污染物  有机磷酸酯  有害结局路径网络  计算毒理学  风险预测与评估  
Effects of an Episodic Storm-Induced Flooding Event on the Biogeochemistry of a Shallow, Highly Turbid, Semi-Enclosed Embayment (Laizhou Bay, Bohai Sea) 期刊论文
SUSTAINABILITY, 2023, 卷号: 15, 期号: 1, 页码: 12
Authors:  Meng, Ling;  Xing, Qianguo;  Gao, Xuelu;  Ji, Diansheng;  Qu, Fanzhu;  Wang, Xiaoqing;  Ji, Ling
Favorite  |  View/Download：26/0  |  Submit date：2023/08/17
episodic flood  freshwater inflows  biogeochemical indicators  chlorophyll a  Laizhou Bay  
Potential adverse outcome pathways with hazard identification of organophosphate esters 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 卷号: 851, 页码: 13
Authors:  Wang, Xiaoqing;  Li, Fei;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
Favorite  |  View/Download：115/0  |  Submit date：2023/01/11
Organophosphate esters (OPEs)  Network-centric analysis  Risk assessment  Adverse outcome pathway  Quantitative weight of evidence  
Critical features identification for chemical chronic toxicity based on mechanistic forecast models 期刊论文
ENVIRONMENTAL POLLUTION, 2022, 卷号: 307, 页码: 8
Authors:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
Favorite  |  View/Download：199/0  |  Submit date：2022/07/26
Computational toxicology  Machine learning  Structural alerts  Risk assessment  Prioritization rank  
Critical target identification and human health risk ranking of metal ions based on mechanism-driven modeling 期刊论文
CHEMOSPHERE, 2022, 卷号: 301, 页码: 9
Authors:  Wang, Xiaoqing;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng;  Li, Fei
Favorite  |  View/Download：166/0  |  Submit date：2022/07/26
Metal ions  p53  QSAR  Genetic toxicity  Human health risk  
Toxicity pathways of lipid metabolic disorders induced by typical replacement flame retardants via data-driven analysis, in silico and in vitro approaches 期刊论文
CHEMOSPHERE, 2022, 卷号: 287, 页码: 9
Authors:  Wang, Xiaoqing;  Wang, Li;  Li, Fei;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
Favorite  |  View/Download：156/0  |  Submit date：2022/06/16
Toxicity pathways  Lipid metabolism disorder  Bibliometric analysis  Computational toxicology  Data-driven analysis  
Graphene-triphenyl phosphate (TPP) co-exposure in the marine environment: Interference with metabolism and immune regulation in mussel Mytilus galloprovincialis 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 卷号: 227, 页码: 8
Authors:  Li, Fei;  Meng, Xiangjing;  Wang, Xiaoqing;  Ji, Chenglong;  Wu, Huifeng
Favorite  |  View/Download：154/0  |  Submit date：2022/06/16
Nanomaterials  Graphene  Organophosphorus ester (OPEs)  Mytilus  Joint effects  Multi-omics  
Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
Authors:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
View  |  Adobe PDF(3938Kb)  |  Favorite  |  View/Download：522/215  |  Submit date：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
Authors:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
View  |  Adobe PDF(6774Kb)  |  Favorite  |  View/Download：275/33  |  Submit date：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity