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Toxicity pathways of lipid metabolic disorders induced by typical replacement flame retardants via data-driven analysis, in silico and in vitro approaches 期刊论文
CHEMOSPHERE, 2022, 卷号: 287, 页码: 9
作者:  Wang, Xiaoqing;  Wang, Li;  Li, Fei;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：237/0  |  提交时间：2022/06/16
Toxicity pathways  Lipid metabolism disorder  Bibliometric analysis  Computational toxicology  Data-driven analysis  
Environmentally relevant concentrations of microplastics influence the locomotor activity of aquatic biota 期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2021, 卷号: 414, 页码: 10
作者:  Sun, Tao;  Zhan, Junfei;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(4268Kb)  |  收藏  |  浏览/下载：701/345  |  提交时间：2021/10/20
Microplastics  Aquatic biota  Locomotor activity  Environmentally relevant concentrations  Meta-analysis  
Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：717/292  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：389/53  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
Toxicological effects of As (V) in juvenile rockfish Sebastes schlegelii by a combined metabolomic and proteomic approach 期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: 255, 期号: 2, 页码: 113333
作者:  Xu, LL;  Lu, Z;  Ji, CL;  Cong, M;  Li, F;  Shan, XJ;  Wu, HF
Adobe PDF(1885Kb)  |  收藏  |  浏览/下载：556/290  |  提交时间：2020/07/08
Arsenic  Toxicological effect  Juvenile rockfish  Proteomics  Metabolomics  
Differential biological effects in two pedigrees of clam Ruditapes philippinarum exposed to cadmium using iTRAQ-based proteomics 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2019, 卷号: 65, 页码: 66-72
作者:  Lu, Zhen;  Wang, Shuang;  Shan, Xiujuan;  Ji, Chenglong;  Wu, Huifeng
Adobe PDF(875Kb)  |  收藏  |  浏览/下载：728/468  |  提交时间：2020/07/08
Ruditapes philippinarum  Pedigrees  Cadmium  Proteomic profiling  
H-1 NMR-based metabolomics study on the physiological variations during the rat pregnancy process 期刊论文
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2016, 卷号: 423, 期号: C, 页码: 40-50
作者:  Shen, GP;  Li, ZS;  Zhang, Y;  Wu, HF;  Feng, JH;  Feng, JH (reprint author), Xiamen Univ, Dept Elect Sci, Fujian Prov Key Lab Plasma & Magnet Resonance, Xiamen 361005, Peoples R China. jianghua.feng@xmu.edu.cn
浏览  |  Adobe PDF(2812Kb)  |  收藏  |  浏览/下载：3789/432  |  提交时间：2016/05/24
Gestation Period  Nmr  Metabolomics  Pattern Recognition  Physiological Variation  
Proteomic and metabolomic responses of clam Ruditapes philippinarum to arsenic exposure under different salinities 期刊论文
AQUATIC TOXICOLOGY, 2013, 卷号: 136, 页码: 91-100
作者:  Wu, Huifeng;  Liu, Xiaoli;  Zhang, Xingyan;  Ji, Chenglong;  Zhao, Jianmin;  Yu, Junbao
浏览  |  Adobe PDF(1417Kb)  |  收藏  |  浏览/下载：1138/432  |  提交时间：2014/07/08
Toxicological Effect  Salinity  Arsenic  Ruditapes Philippinarum  Proteomics  Metabolomics  
Towards a System Level Understanding of Non-Model Organisms Sampled from the Environment: A Network Biology Approach 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2011, 卷号: 7, 期号: 8, 页码: e1002126
作者:  Williams, Tim D.;  Turan, Nil;  Diab, Amer M.;  Wu, Huifeng;  Mackenzie, Carolynn;  Bartie, Katie L.;  Hrydziuszko, Olga;  Lyons, Brett P.;  Stentiford, Grant D.;  Herbert, John M.;  Abraham, Joseph K.;  Katsiadaki, Ioanna;  Leaver, Michael J.;  Taggart, John B.;  George, Stephen G.;  Viant, Mark R.;  Chipman, Kevin J.;  Falciani, Francesco
浏览  |  Adobe PDF(1348Kb)  |  收藏  |  浏览/下载：1079/230  |  提交时间：2011/11/11
Flounder Platichthys-flesus  Histopathological Biomarkers  Pleuronectes-platessa  Endocrine Disruption  Gene-expression  Liver Fibrosis  Marine Fish  Receptor  Microarray  Proteasome  
Assessment of Clam Ruditapes philippinarum as Heavy Metal Bioindicators Using NMR-Based Metabolomics 期刊论文
CLEAN-SOIL AIR WATER, 2011, 卷号: 39, 期号: 8, 页码: 759-766
作者:  Liu, Xiaoli;  Zhang, Linbao;  You, Liping;  Yu, Junbao;  Cong, Ming;  Wang, Qing;  Li, Fei;  Li, Lianzhen;  Zhao, Jianmin;  Li, Chenghua;  Wu, Huifeng
浏览  |  Adobe PDF(600Kb)  |  收藏  |  浏览/下载：1490/437  |  提交时间：2011/11/11
Bioindicator  Manila Clam  Mercury  Metabolomics  Nmr