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Molecular diversity and evolution of defensins in the manila clam Ruditapes philippinarum 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2015, 卷号: 47, 期号: 1, 页码: 302-312
作者:  Wang, Q;  Zhang, LB;  Yang, DL;  Yu, Q;  Li, F;  Cong, M;  Ji, CL;  Wu, HF;  Zhao, JM;  Zhao, JM (reprint author), Chinese Acad Sci, Key Lab Coastal Environm Processes & Ecol Remedia, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China. jmzhao@yic.ac.cn
浏览  |  Adobe PDF(1687Kb)  |  收藏  |  浏览/下载：625/274  |  提交时间：2016/04/24
Defensin  Manila Clam  Diversity  Positive Selection  
典型持久性有机污染物与抑癌基因相互作用的分子模拟与验证 期刊论文
科学通报, 2015, 卷号: 60, 期号: 19, 页码: 1804-1809
作者:  吴惠丰;  曹璐璐;  李斐;  李雪花;  赵建民
浏览  |  Adobe PDF(1577Kb)  |  收藏  |  浏览/下载：698/315  |  提交时间：2016/12/15
持久性有机污染物  P53  2  分子模拟  2'  光谱法  4  4'-四溴联苯醚(Bde-47)  
A defensin from clam Venerupis philippinarum: Molecular characterization, localization, antibacterial activity, and mechanism of action 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2015, 卷号: 51, 期号: 1, 页码: 29-38
作者:  Zhang, LB;  Yang, DL;  Wang, Q;  Yuan, ZY;  Wu, HF;  Pei, D;  Cong, M;  Li, F;  Ji, CL;  Zhao, JM;  Wu, HF (reprint author), YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
浏览  |  Adobe PDF(3713Kb)  |  收藏  |  浏览/下载：538/177  |  提交时间：2016/04/24
Venerupis Philippinarum  Defensin  Molecular Characterization  Tissue Distribution  Antimicrobial Activity  Membrane Lesions  
Multiple biomarkers of the cytotoxicity induced by BDE-47 in human embryonic kidney cells 期刊论文
CHEMOSPHERE, 2015, 卷号: 126, 页码: 32-39
作者:  Wu, Huifeng;  Cao, Lulu;  Li, Fei;  Lian, Peiwen;  Zhao, Jianmin;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn
浏览  |  Adobe PDF(765Kb)  |  收藏  |  浏览/下载：869/376  |  提交时间：2015/07/31
Bde-47  Hek293 Cells  Cytotoxicity  Cell Apoptosis  Ros  Metabolomics  
Glutathione S-transferase (GST) gene expression profiles in two marine bivalves exposed to BDE-47 and their potential molecular mechanisms 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2015, 卷号: 33, 期号: 3, 页码: 705-713
作者:  Li Fei;  Wu Huifeng;  Wang Qing;  Li Xuehua;  Zhao Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(580Kb)  |  收藏  |  浏览/下载：851/287  |  提交时间：2015/07/31
Glutathione S-transferase (Gst)  Venerupis Philippinarum  Mytilus Galloprovincialis  Molecular Docking  2  Biomarker  2 '  4  4 '-tetrabromodiphenyl Ether (Bde-47)  
Combined metabolome and proteome analysis of the mantle tissue from Pacific oyster Crassostrea gigas exposed to elevated pCO(2) 期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS, 2015, 卷号: 13, 页码: 16-23
作者:  Wei, Lei;  Wang, Qing;  Ning, Xuanxuan;  Mu, Changkao;  Wang, Chunlin;  Cao, Ruiwen;  Wu, Huifeng;  Cong, Ming;  Li, Fei;  Ji, Chenglong;  Zhao, Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
浏览  |  Adobe PDF(588Kb)  |  收藏  |  浏览/下载：967/424  |  提交时间：2015/07/31
Ocean Acidification  Proteomics  Metabolomics  Crassostrea Gigas  
BDE-47对人胚肾细胞HEK293的毒理效应及作用机制 期刊论文
生态毒理学报, 2015, 卷号: ., 期号: 2, 页码: 236-242
作者:  曹璐璐;  李斐;  吴惠丰;  赵建民
浏览  |  Adobe PDF(304Kb)  |  收藏  |  浏览/下载：389/160  |  提交时间：2021/06/16
2,2’,4,4’-四溴联苯醚（BDE-47）  人胚肾细胞  细胞凋亡  氧化损伤  p53  Bax  
海岸带污染物联合毒性的预测及评价 期刊论文
海岸科学, 2015, 卷号: 第2卷, 期号: 第1期, 页码: 27-36
作者:  于德良 李斐 吴惠丰 赵建民;  李斐
Adobe PDF(1159Kb)  |  收藏  |  浏览/下载：514/157  |  提交时间：2018/04/10
海岸带污染物  联合毒性  浓度加和  独立作用