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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：720/292  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
The critical factors affecting typical organophosphate flame retardants to mimetic biomembrane: An integrated in vitro and in silico study 期刊论文
CHEMOSPHERE, 2019, 卷号: 226, 页码: 159-165
作者:  Wang, XQ;  Meng, XJ;  Li, F;  Ding, JW;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(969Kb)  |  收藏  |  浏览/下载：497/209  |  提交时间：2020/07/08
Organophosphate flame retardants (OPFRs)  Quantitative structure-activity relationship (QSAR)  Mimetic biomembrane  Electrochemical impedance spectroscopy (EIS)  Partial least squares (PLS)  
Biological effects of tris (1-chloro-2-propyl) phosphate (TCPP) on immunity in mussel Mytilus galloprovincialis 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2018, 卷号: 61, 页码: 102-106
作者:  Wu, Huifeng;  Zhong, Mingyu;  Lu, Zhen;  Shan, Xiujuan;  Li, Fei;  Ji, Chenglong;  Cong, Ming
浏览  |  Adobe PDF(1041Kb)  |  收藏  |  浏览/下载：539/304  |  提交时间：2020/07/08
Organophosphate flame retardants (OPFRs)  Tris (2-chloropropyl) phosphate (TCPP)  Biological effects  InununityMytilus galloprovincialis  
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(2093Kb)  |  收藏  |  浏览/下载：807/289  |  提交时间：2015/07/31
Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)  
iTRAQ-based quantitative proteomic analyses on the gender-specific responses in mussel Mytilus galloprovincialis to tetrabromobisphenol A 期刊论文
AQUATIC TOXICOLOGY, 2014, 卷号: 157, 页码: 30-40
作者:  Ji, Chenglong;  Wu, Huifeng;  Wei, Lei;  Zhao, Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(2729Kb)  |  收藏  |  浏览/下载：807/345  |  提交时间：2015/07/31
Tetrabromobisphenol a  Toxicological Effects  Mytilus Galloprovincialis  Itraq  Proteomics  
A Novel C-Type Lysozyme from Mytilus galloprovincialis: Insight into Innate Immunity and Molecular Evolution of Invertebrate C-Type Lysozymes 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 6, 页码: e67469
作者:  Wang, Qing;  Wang, Chunyan;  Mu, Changkao;  Wu, Huifeng;  Zhang, Linbao;  Zhao, Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
浏览  |  Adobe PDF(7074Kb)  |  收藏  |  浏览/下载：964/165  |  提交时间：2014/07/08
Egg-white Lysozyme  Expression Analysis  Drosophila-melanogaster  Maximum-likelihood  Positive Selection  Shrimp Lysozyme  Gene-expression  Salivary-glands  Lytic Activity  Bombyx-mori  
Molecular characterization of a manganese superoxide dismutase and copper/zinc superoxide dismutase from the mussel Mytilus galloprovincialis 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2013, 卷号: 34, 期号: 5, 页码: 1345-1351
作者:  Wang, Qing;  Yuan, Zeyi;  Wu, Huifeng;  Liu, Feng;  Zhao, Jianmin
浏览  |  Adobe PDF(1121Kb)  |  收藏  |  浏览/下载：935/297  |  提交时间：2013/08/15
Superoxide Dismutase  Mytilus Galloprovincialis  Bacterial Challenge  Immune Responses  
Docking and QSAR study on the binding interactions between polycyclic aromatic hydrocarbons and estrogen receptor 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2012, 卷号: 80, 页码: 273-279
作者:  Li, Fei;  Wu, Huifeng;  Li, Lianzhen;  Li, Xuehua;  Zhao, Jianmin;  Peijnenburg, Willie J. G. M.
Adobe PDF(450Kb)  |  收藏  |  浏览/下载：1086/426  |  提交时间：2013/03/08
Polycyclic Aromatic Hydrocarbons (Pahs)  Estrogenic Activity  Molecular Docking  Quantitative Structure-activity Relationship (Qsar)  Applicability Domain  
Uptake pathways and subcellular fractionation of Cd in the polychaete Nereis diversicolor 期刊论文
ECOTOXICOLOGY, 2012, 卷号: 21, 期号: 1, 页码: 104-110
作者:  Li, Lianzhen;  Liu, Xiaoli;  You, Liping;  Zhang, Linbao;  Zhao, Jianmin;  Wu, Huifeng
浏览  |  Adobe PDF(301Kb)  |  收藏  |  浏览/下载：1316/343  |  提交时间：2012/06/13
Cd  Uptake Mechanism  Metal Accumulation  Nereis Diversicolor  
Docking and 3D-QSAR studies on the Ah receptor binding affinities of polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2011, 卷号: 32, 期号: 3, 页码: 478-485
作者:  Li, Fei;  Li, Xuehua;  Liu, Xiaoli;  Zhang, Linbao;  You, Liping;  Zhao, Jianmin;  Wu, Huifeng
浏览  |  Adobe PDF(398Kb)  |  收藏  |  浏览/下载：1970/591  |  提交时间：2012/03/06
Qsar  Docking  Partial Least Squares  Polychlorinated Biphenyls (Pcbs)  Dibenzo-p-dioxins (Pcdds)  Dibenzofurans (Pcdfs)