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A defensin-like antimicrobial peptide from the manila clam Ruditapes philippinarum: Investigation of the antibacterial activities and mode of action 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2018, 卷号: 80, 页码: 274-280
作者:  Yang, Dinglong;  Zhang, Qianqian;  Wang, Qing;  Chen, Lizhu;  Liu, Yongliang;  Cong, Ming;  Wu, Huifeng;  Li, Fei;  Ji, Chenglong;  Zhao, Jianmin
收藏  |  浏览/下载：592/0  |  提交时间：2018/09/18
Ruditapes philippinarum  Defensin  Antimicrobial activity  Membrane disruption  
A defensin from clam Venerupis philippinarum: Molecular characterization, localization, antibacterial activity, and mechanism of action 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2015, 卷号: 51, 期号: 1, 页码: 29-38
作者:  Zhang, LB;  Yang, DL;  Wang, Q;  Yuan, ZY;  Wu, HF;  Pei, D;  Cong, M;  Li, F;  Ji, CL;  Zhao, JM;  Wu, HF (reprint author), YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
浏览  |  Adobe PDF(3713Kb)  |  收藏  |  浏览/下载：538/177  |  提交时间：2016/04/24
Venerupis Philippinarum  Defensin  Molecular Characterization  Tissue Distribution  Antimicrobial Activity  Membrane Lesions  
Multiple biomarkers of the cytotoxicity induced by BDE-47 in human embryonic kidney cells 期刊论文
CHEMOSPHERE, 2015, 卷号: 126, 页码: 32-39
作者:  Wu, Huifeng;  Cao, Lulu;  Li, Fei;  Lian, Peiwen;  Zhao, Jianmin;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn
浏览  |  Adobe PDF(765Kb)  |  收藏  |  浏览/下载：869/376  |  提交时间：2015/07/31
Bde-47  Hek293 Cells  Cytotoxicity  Cell Apoptosis  Ros  Metabolomics  
iTRAQ-based quantitative proteomic analyses on the gender-specific responses in mussel Mytilus galloprovincialis to tetrabromobisphenol A 期刊论文
AQUATIC TOXICOLOGY, 2014, 卷号: 157, 页码: 30-40
作者:  Ji, Chenglong;  Wu, Huifeng;  Wei, Lei;  Zhao, Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(2729Kb)  |  收藏  |  浏览/下载：804/343  |  提交时间：2015/07/31
Tetrabromobisphenol a  Toxicological Effects  Mytilus Galloprovincialis  Itraq  Proteomics  
Determination and Prediction of the Binding Interaction between Organophosphate Flame Retardants and p53 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2014, 卷号: 27, 期号: 11, 页码: 1918-1925
作者:  Li, Fei;  Yang, Xianhai;  Li, Xuehua;  Li, Renmin;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
浏览  |  Adobe PDF(1104Kb)  |  收藏  |  浏览/下载：839/379  |  提交时间：2015/07/31
Polybrominated Diphenyl Ethers  Thyroid-hormone Receptors  Structural Requirements  Surface Waters  In-silico  Plasticizers  Complex  Air  Regression  Zebrafish  
The interaction between organic phosphate ester and p53: An integrated experimental and in silico approach 期刊论文
MARINE POLLUTION BULLETIN, 2014, 卷号: 85, 期号: 2, 页码: 516-521
作者:  Li, Fei;  Li, Renmin;  Yang, Xianhai;  You, Liping;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, YICCAS, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
浏览  |  Adobe PDF(915Kb)  |  收藏  |  浏览/下载：621/230  |  提交时间：2015/07/31
Organophosphate Flame Retardants (Opfrs) P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Multiple Linear Regression (Mlr)  
Identification and mRNA expression of two 17 beta-hydroxysteroid dehydrogenase genes in the marine mussel Mytilus galloprovincialis following exposure to endocrine disrupting chemicals 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2014, 卷号: 37, 期号: 3, 页码: 1243-1255
作者:  Zhang, Yingying;  Wang, Qing;  Ji, Yinglu;  Zhang, Qian;  Wu, Huifeng;  Xie, Jia;  Zhao, Jianmin;  Zhao, JM (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Zone Environm Proc & Ecol Re, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
浏览  |  Adobe PDF(3979Kb)  |  收藏  |  浏览/下载：625/217  |  提交时间：2015/07/31
17 Beta-hydroxysteroid  Dehydrogenases  Mytilus Galloprovincialis  Digestive Glands  Endocrine Disrupting Chemicals  Gene Expression  
Proteomic and metabolomic analysis of earthworm Eisenia fetida exposed to different concentrations of 2,2 ',4,4 '-tetrabromodiphenyl ether 期刊论文
JOURNAL OF PROTEOMICS, 2013, 卷号: 91, 页码: 405-416
作者:  Ji, Chenglong;  Wu, Huifeng;  Wei, Lei;  Zhao, Jianmin;  Lu, Hongjian;  Yu, Junbao
浏览  |  Adobe PDF(1511Kb)  |  收藏  |  浏览/下载：1075/299  |  提交时间：2014/07/08
Proteomics  Metabolomics  Eisenia Fetida  Bde 47  
Proteomic and metabolomic analysis reveal gender-specific responses of mussel Mytilus galloprovincialis to 2,2 ',4,4 '-tetrabromodiphenyl ether (BDE 47) 期刊论文
AQUATIC TOXICOLOGY, 2013, 卷号: 140, 页码: 449-457
作者:  Ji, Chenglong;  Wu, Huifeng;  Wei, Lei;  Zhao, Jianmin;  Yu, Junbao
浏览  |  Adobe PDF(1895Kb)  |  收藏  |  浏览/下载：946/222  |  提交时间：2014/07/08
Bde 47  Mytilus Galloprovincialis  Toxicological Effects  Proteomics  Metabolomics  
Proteomic and metabolomic responses of clam Ruditapes philippinarum to arsenic exposure under different salinities 期刊论文
AQUATIC TOXICOLOGY, 2013, 卷号: 136, 页码: 91-100
作者:  Wu, Huifeng;  Liu, Xiaoli;  Zhang, Xingyan;  Ji, Chenglong;  Zhao, Jianmin;  Yu, Junbao
浏览  |  Adobe PDF(1417Kb)  |  收藏  |  浏览/下载：1138/432  |  提交时间：2014/07/08
Toxicological Effect  Salinity  Arsenic  Ruditapes Philippinarum  Proteomics  Metabolomics