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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
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Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Global characterization of dose-dependent effects of cadmium in clam Ruditapes philippinarum 期刊论文
ENVIRONMENTAL POLLUTION, 2021, 卷号: 273, 页码: 9
作者:  Zhan, Junfei;  Wang, Shuang;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
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Benchmark dose  Cadmium  Dose-dependent effects  Ruditapes philippinarum  Transcriptomics  
Evaluation on the biomagnification or biodilution of trace metals in global marine food webs by meta-analysis 期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 264, 页码: 11
作者:  Sun, Tao;  Wu, Huifeng;  Wang, Xiaoqing;  Ji, Chenglong;  Shan, Xiujuan;  Li, Fei
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Trace metals  Marine food webs  Metal concentration  Trophic transfer  Marine environment  
Toxicological effects of As (V) in juvenile rockfish Sebastes schlegelii by a combined metabolomic and proteomic approach 期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: 255, 期号: 2, 页码: 113333
作者:  Xu, LL;  Lu, Z;  Ji, CL;  Cong, M;  Li, F;  Shan, XJ;  Wu, HF
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Arsenic  Toxicological effect  Juvenile rockfish  Proteomics  Metabolomics  
Differential biological effects in two pedigrees of clam Ruditapes philippinarum exposed to cadmium using iTRAQ-based proteomics 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2019, 卷号: 65, 页码: 66-72
作者:  Lu, Zhen;  Wang, Shuang;  Shan, Xiujuan;  Ji, Chenglong;  Wu, Huifeng
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Ruditapes philippinarum  Pedigrees  Cadmium  Proteomic profiling  
The role of GST omega in metabolism and detoxification of arsenic in clam Ruditapes philippinarum 期刊论文
AQUATIC TOXICOLOGY, 2018, 卷号: 204, 页码: 9-18
作者:  Chen, Lizhu;  Wu, Huifeng;  Zhao, Jianmin;  Zhang, Wei;  Zhang, Li;  Sun, Shan;  Yang, Dinglong;  Cheng, Bo;  Wang, Qing
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Arsenic  Bioaccumulation  Metabolism  Subcellular distribution  Glutathione S-transferase omega  
Digital gene expression analysis in the gills of Ruditapes philippinarum exposed to short- and long-term exposures of ammonia nitrogen 期刊论文
AQUATIC TOXICOLOGY, 2018, 卷号: 194, 页码: 121-131
作者:  Cong, Ming;  Wu, Huifeng;  Cao, Tengfei;  Lv, Jiasen;  Wang, Qing;  Ji, Chenglong;  Li, Chenghua;  Zhao, Jianmin
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Ruditapes philippinarum  Digital gene expression  Transcriptome  Ammonia nitrogen  Toxicity  
Differential metabolic responses in three life stages of mussels Mytilus galloprovincialis exposed to cadmium 期刊论文
ECOTOXICOLOGY, 2017, 卷号: 26, 期号: 1, 页码: 74-80
作者:  Wu, Huifeng;  Xu, Lanlan;  Yu, Deliang;  Ji, Chenglong;  Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
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Mytilus Galloprovincialis  Cadmium  Toxicological Effects  Nmr  Metabolomics  
Proteomic and metabolomic responses in D-shape larval mussels Mytilus galloprovincialis exposed to cadmium and arsenic 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2016, 卷号: 58, 页码: 514-520
作者:  Wu, Huifeng;  Xu, Lanlan;  Ji, Chenglong;  Yu, Deliang;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, YICCAS, Key Lab Coastal Zone Environm Proc,Yantai Inst Co, Yantai 264003, Peoples R China. Email:hfwu@yic.ac.cn
浏览  |  Adobe PDF(921Kb)  |  收藏  |  浏览/下载:703/309  |  提交时间:2016/12/19
Mytilus Galloprovincialis  Cadmium  Arsenic  Biological Effects  Proteomics  Metabolomics  
Homologous cloning, characterization and expression of a new halophyte phytochelatin synthase gene in Suaeda salsa 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2016, 卷号: 34, 期号: 5, 页码: 1034-1043
作者:  Cong, M;  Zhao, JM;  Lu, JS;  Ren, ZM;  Wu, HF;  Wu, HF (reprint author), Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(435Kb)  |  收藏  |  浏览/下载:712/319  |  提交时间:2016/10/08
Suaeda Salsa  Halophyte  Phytochelatin Synthase (Pcs)  Homologous Cloning  Heavy Metal  Tissue Distribution