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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：774/299  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：431/54  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
Profiling of microRNAs and mRNAs in marine mussel Mytilus galloprovincialis 期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2020, 卷号: 230, 页码: 108697
作者:  Yu, Deliang;  Wu, Huifeng;  Peng, Xiao;  Ji, Chenglong;  Zhang, Xiaoying;  Song, Jun;  Qu, Junle
浏览  |  Adobe PDF(1152Kb)  |  收藏  |  浏览/下载：732/305  |  提交时间：2020/07/08
CUCUMBER APOSTICHOPUS-JAPONICUS  OYSTER OSTREA-EDULIS  METABOLOMIC ANALYSIS  OXIDATIVE STRESS  DIGESTIVE GLAND  LET-7  EXPRESSION  MIRNAS  IDENTIFICATION  DROSOPHILA  
Digital gene expression analysis in the gills of Ruditapes philippinarum after nitrite exposure 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 184, 页码: 7
作者:  Lv, Jiasen;  Cao, Tengfei;  Ji, Chenglong;  Cong, Ming;  Zhao, Jianmin;  Wu, Huifeng
浏览  |  Adobe PDF(594Kb)  |  收藏  |  浏览/下载：484/194  |  提交时间：2021/06/22
Digital gene expression  Gills  Ruditapes philippinarum  Nitrite  
Digital gene expression analysis in the gills of Ruditapes philippinarum exposed to short- and long-term exposures of ammonia nitrogen 期刊论文
AQUATIC TOXICOLOGY, 2018, 卷号: 194, 页码: 121-131
作者:  Cong, Ming;  Wu, Huifeng;  Cao, Tengfei;  Lv, Jiasen;  Wang, Qing;  Ji, Chenglong;  Li, Chenghua;  Zhao, Jianmin
浏览  |  Adobe PDF(938Kb)  |  收藏  |  浏览/下载：937/560  |  提交时间：2020/07/08
Ruditapes philippinarum  Digital gene expression  Transcriptome  Ammonia nitrogen  Toxicity  
Proteomic and metabolomic responses in D-shape larval mussels Mytilus galloprovincialis exposed to cadmium and arsenic 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2016, 卷号: 58, 页码: 514-520
作者:  Wu, Huifeng;  Xu, Lanlan;  Ji, Chenglong;  Yu, Deliang;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, YICCAS, Key Lab Coastal Zone Environm Proc,Yantai Inst Co, Yantai 264003, Peoples R China. Email:hfwu@yic.ac.cn
浏览  |  Adobe PDF(921Kb)  |  收藏  |  浏览/下载：709/311  |  提交时间：2016/12/19
Mytilus Galloprovincialis  Cadmium  Arsenic  Biological Effects  Proteomics  Metabolomics  
Homologous cloning, characterization and expression of a new halophyte phytochelatin synthase gene in Suaeda salsa 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2016, 卷号: 34, 期号: 5, 页码: 1034-1043
作者:  Cong, M;  Zhao, JM;  Lu, JS;  Ren, ZM;  Wu, HF;  Wu, HF (reprint author), Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(435Kb)  |  收藏  |  浏览/下载：718/322  |  提交时间：2016/10/08
Suaeda Salsa  Halophyte  Phytochelatin Synthase (Pcs)  Homologous Cloning  Heavy Metal  Tissue Distribution  
H-1 NMR-based metabolomics study on the physiological variations during the rat pregnancy process 期刊论文
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2016, 卷号: 423, 期号: C, 页码: 40-50
作者:  Shen, GP;  Li, ZS;  Zhang, Y;  Wu, HF;  Feng, JH;  Feng, JH (reprint author), Xiamen Univ, Dept Elect Sci, Fujian Prov Key Lab Plasma & Magnet Resonance, Xiamen 361005, Peoples R China. jianghua.feng@xmu.edu.cn
浏览  |  Adobe PDF(2812Kb)  |  收藏  |  浏览/下载：3978/470  |  提交时间：2016/05/24
Gestation Period  Nmr  Metabolomics  Pattern Recognition  Physiological Variation  
典型持久性有机污染物与抑癌基因相互作用的分子模拟与验证 期刊论文
科学通报, 2015, 卷号: 60, 期号: 19, 页码: 1804-1809
作者:  吴惠丰;  曹璐璐;  李斐;  李雪花;  赵建民
浏览  |  Adobe PDF(1577Kb)  |  收藏  |  浏览/下载：720/317  |  提交时间：2016/12/15
持久性有机污染物  P53  2  分子模拟  2'  光谱法  4  4'-四溴联苯醚(Bde-47)  
Determination and Prediction of the Binding Interaction between Organophosphate Flame Retardants and p53 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2014, 卷号: 27, 期号: 11, 页码: 1918-1925
作者:  Li, Fei;  Yang, Xianhai;  Li, Xuehua;  Li, Renmin;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
浏览  |  Adobe PDF(1104Kb)  |  收藏  |  浏览/下载：880/395  |  提交时间：2015/07/31
Polybrominated Diphenyl Ethers  Thyroid-hormone Receptors  Structural Requirements  Surface Waters  In-silico  Plasticizers  Complex  Air  Regression  Zebrafish