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Dose-dependent responses of metabolism and tissue injuries in clam Ruditapes philippinarum after subchronic exposure to cadmium 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2021, 卷号: 779, 页码: 11
作者:  Zhan, Junfei;  Wang, Shuang;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
Adobe PDF(2610Kb)  |  收藏  |  浏览/下载：550/279  |  提交时间：2021/10/20
Cadmium  Dose-response  Hormesis  Metabolomics  Ruditapes philippinarum  Tissue injuries  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：389/53  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
An integrated proteomic and metabolomic study on the gender-specific responses of mussels Mytilus galloprovincialis to tetrabromobisphenol A (TBBPA) 期刊论文
CHEMOSPHERE, 2016, 卷号: 144, 页码: 527-539
作者:  Ji, CL;  Li, F;  Wang, Q;  Zhao, JM;  Sun, ZD;  Wu, HF;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Environm Proc, Key Lab Coastal Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
Adobe PDF(2260Kb)  |  收藏  |  浏览/下载：1023/313  |  提交时间：2016/04/24
Gender-specific  Mytilus Galloprovincialis  Proteomics  Metabolomics  Tetrabromobisphenol a  
A defensin from clam Venerupis philippinarum: Molecular characterization, localization, antibacterial activity, and mechanism of action 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2015, 卷号: 51, 期号: 1, 页码: 29-38
作者:  Zhang, LB;  Yang, DL;  Wang, Q;  Yuan, ZY;  Wu, HF;  Pei, D;  Cong, M;  Li, F;  Ji, CL;  Zhao, JM;  Wu, HF (reprint author), YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
浏览  |  Adobe PDF(3713Kb)  |  收藏  |  浏览/下载：538/177  |  提交时间：2016/04/24
Venerupis Philippinarum  Defensin  Molecular Characterization  Tissue Distribution  Antimicrobial Activity  Membrane Lesions  
iTRAQ-based quantitative proteomic analyses on the gender-specific responses in mussel Mytilus galloprovincialis to tetrabromobisphenol A 期刊论文
AQUATIC TOXICOLOGY, 2014, 卷号: 157, 页码: 30-40
作者:  Ji, Chenglong;  Wu, Huifeng;  Wei, Lei;  Zhao, Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
Adobe PDF(2729Kb)  |  收藏  |  浏览/下载：806/345  |  提交时间：2015/07/31
Tetrabromobisphenol a  Toxicological Effects  Mytilus Galloprovincialis  Itraq  Proteomics  
Determination and Prediction of the Binding Interaction between Organophosphate Flame Retardants and p53 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2014, 卷号: 27, 期号: 11, 页码: 1918-1925
作者:  Li, Fei;  Yang, Xianhai;  Li, Xuehua;  Li, Renmin;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
Adobe PDF(1104Kb)  |  收藏  |  浏览/下载：840/379  |  提交时间：2015/07/31
Polybrominated Diphenyl Ethers  Thyroid-hormone Receptors  Structural Requirements  Surface Waters  In-silico  Plasticizers  Complex  Air  Regression  Zebrafish  
The interaction between organic phosphate ester and p53: An integrated experimental and in silico approach 期刊论文
MARINE POLLUTION BULLETIN, 2014, 卷号: 85, 期号: 2, 页码: 516-521
作者:  Li, Fei;  Li, Renmin;  Yang, Xianhai;  You, Liping;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, YICCAS, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
Adobe PDF(915Kb)  |  收藏  |  浏览/下载：621/230  |  提交时间：2015/07/31
Organophosphate Flame Retardants (Opfrs) P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Multiple Linear Regression (Mlr)  
Towards a System Level Understanding of Non-Model Organisms Sampled from the Environment: A Network Biology Approach 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2011, 卷号: 7, 期号: 8, 页码: e1002126
作者:  Williams, Tim D.;  Turan, Nil;  Diab, Amer M.;  Wu, Huifeng;  Mackenzie, Carolynn;  Bartie, Katie L.;  Hrydziuszko, Olga;  Lyons, Brett P.;  Stentiford, Grant D.;  Herbert, John M.;  Abraham, Joseph K.;  Katsiadaki, Ioanna;  Leaver, Michael J.;  Taggart, John B.;  George, Stephen G.;  Viant, Mark R.;  Chipman, Kevin J.;  Falciani, Francesco
Adobe PDF(1348Kb)  |  收藏  |  浏览/下载：1079/230  |  提交时间：2011/11/11
Flounder Platichthys-flesus  Histopathological Biomarkers  Pleuronectes-platessa  Endocrine Disruption  Gene-expression  Liver Fibrosis  Marine Fish  Receptor  Microarray  Proteasome