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Comparative investigations on the biological effects of As (III) and As (V) in clam Ruditapes philippinarum using multiple biomarkers 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2015, 卷号: 47, 期号: 1, 页码: 79-84
作者:  Ji, CL;  Xu, H;  Wang, Q;  Zhao, JM;  Wu, HF;  Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
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Ruditapes Philippinarum  Arsenic  Biological Effects  Metabolomics  
A defensin from clam Venerupis philippinarum: Molecular characterization, localization, antibacterial activity, and mechanism of action 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2015, 卷号: 51, 期号: 1, 页码: 29-38
作者:  Zhang, LB;  Yang, DL;  Wang, Q;  Yuan, ZY;  Wu, HF;  Pei, D;  Cong, M;  Li, F;  Ji, CL;  Zhao, JM;  Wu, HF (reprint author), YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
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Venerupis Philippinarum  Defensin  Molecular Characterization  Tissue Distribution  Antimicrobial Activity  Membrane Lesions  
Multiple biomarkers of biological effects induced by cadmium in clam Ruditapes philippinarum 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2015, 卷号: 44, 期号: 2, 页码: 430-435
作者:  Ji, CL;  Wu, HF;  Zhou, M;  Zhao, JM;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
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Ruditapes Philippinarum  Cadmium  Biological Effects  Metabolomics  
Fractal features of soil particle size distribution in newly formed wetlands in the Yellow River Delta 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Yu, Junbao;  Lv, Xiaofei;  Bin, Ma;  Wu, Huifeng;  Du, Siyao;  Zhou, Mo;  Yang, Yanming;  Han, Guangxuan
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The relations between metabolic variations and genetic evolution of different species 期刊论文
ANALYTICAL BIOCHEMISTRY, 2015, 卷号: 477, 页码: 105-114
作者:  Li, Zhishui;  Lin, Chenghong;  Xu, Jingjing;  Wu, Huifeng;  Feng, Jianghua;  Huang, Heguang;  Feng, JH (reprint author), Xiamen Univ, Fujian Prov Key Lab Plasma & Magnet Resonance, Dept Elect Sci, Xiamen 361005, Peoples R China. jianghua.feng@xmu.edu.cn
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Nmr  Metabonomics  Physiological Variation  Laboratory Animals  Genetic Evolution  
Multiple biomarkers of the cytotoxicity induced by BDE-47 in human embryonic kidney cells 期刊论文
CHEMOSPHERE, 2015, 卷号: 126, 页码: 32-39
作者:  Wu, Huifeng;  Cao, Lulu;  Li, Fei;  Lian, Peiwen;  Zhao, Jianmin;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn
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Bde-47  Hek293 Cells  Cytotoxicity  Cell Apoptosis  Ros  Metabolomics  
Glutathione S-transferase (GST) gene expression profiles in two marine bivalves exposed to BDE-47 and their potential molecular mechanisms 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2015, 卷号: 33, 期号: 3, 页码: 705-713
作者:  Li Fei;  Wu Huifeng;  Wang Qing;  Li Xuehua;  Zhao Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
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Glutathione S-transferase (Gst)  Venerupis Philippinarum  Mytilus Galloprovincialis  Molecular Docking  2  Biomarker  2 '  4  4 '-tetrabromodiphenyl Ether (Bde-47)  
Changes of Soil Particle Size Distribution in Tidal Flats in the Yellow River Delta 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 3, 页码: e0121368
作者:  Lyu, Xiaofei;  Yu, Junbao;  Zhou, Mo;  Ma, Bin;  Wang, Guangmei;  Zhan, Chao;  Han, Guangxuan;  Guan, Bo;  Wu, Huifeng;  Li, Yunzhao;  Wang, De;  Yu, JB (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai, Shandong, Peoples R China. junbao.yu@gmail.com
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Land-use Types  Fractal Features  Spatial-patterns  China  Sediment  Wetland  Fragmentation  Variability  Accretion  Salinity  
Combined metabolome and proteome analysis of the mantle tissue from Pacific oyster Crassostrea gigas exposed to elevated pCO(2) 期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS, 2015, 卷号: 13, 页码: 16-23
作者:  Wei, Lei;  Wang, Qing;  Ning, Xuanxuan;  Mu, Changkao;  Wang, Chunlin;  Cao, Ruiwen;  Wu, Huifeng;  Cong, Ming;  Li, Fei;  Ji, Chenglong;  Zhao, Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
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Ocean Acidification  Proteomics  Metabolomics  Crassostrea Gigas  
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
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Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)