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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
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Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
磷酸三苯酯(TPP)和磷酸三(2-氯异丙基)酯(TCPP)诱导人胚肾细胞HEK293凋亡的机制研究 期刊论文
生态毒理学报, 2019, 卷号: 14, 期号: 5, 页码: 123-132
作者:  王晓晴;  刘佳琳;  李斐;  曹天贵;  吴惠丰;  孟祥敬;  吉成龙
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有机磷酸酯阻燃剂  磷酸三(2-氯异丙基)酯(Tcpp)  磷酸三苯酯(Tpp)  肾细胞  细胞凋亡  Organophosphate Flame Retardant  Tris (2-chloroisopropyl) Phosphate (Tcpp)  Triphenyl Phosphate(Tpp)  Kidney Cell  Apoptosis  
Interaction between organic phosphate ester and p53: An integrated experimental and in silico approach 期刊论文
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 卷号: 255
作者:  Li, Fei
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An integrative biomarker approach to assess the environmental stress in the north coast of Shandong Peninsula using native oysters, Crassostrea gigas (vol 112, pg 318, 2016) 期刊论文
MARINE POLLUTION BULLETIN, 2016, 卷号: 113, 期号: 1-2, 页码: 600-600
作者:  Xie, Jia;  Zhao, Yun;  Wang, Qing;  Wu, Huifeng;  Teng, Jia;  Yang, Dinglong;  Cao, Iwen;  Chen, Lizhu;  Li, Fei;  Ji, Chenglong;  Cong, Ming;  Zhao, Jianmin;  Zhao, JM (reprint author), Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Peoples R China. jmzhao@yic.ac.cn
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An integrative biomarker approach to assess the environmental stress in the north coast of Shandong Peninsula using native oysters, Crassostrea gigas 期刊论文
MARINE POLLUTION BULLETIN, 2016, 卷号: 112, 期号: 1-2, 页码: 318-326
作者:  Xie, J;  Zhao, Y;  Wang, Q;  Wu, HF;  Teng, J;  Yang, DL;  Cao, RW;  Chen, LZ;  Zhang, YJ;  Li, F;  Ji, CL;  Cong, M;  Zhao, JM;  Zhao, JM (reprint author), Chinese Acad Sci, Yantai Inst CoastalZone Res YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China.
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Biomarkers  Crassostrea Gigas  Metals  Integrative Indices  
Rational Selection of the 3D Structure of Biomacromolecules for Molecular Docking Studies on the Mechanism of Endocrine Disruptor Action 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 卷号: 29, 期号: 9, 页码: 1565-1570
作者:  Yang, Xianhai;  Liu, Huihui;  Liu, Jining;  Li, Fei;  Li, Xuehua;  Shi, Lili;  Chen, Jingwen;  Liu, JB (reprint author) Minist Environm Protect, Nanjing Inst Environm Sci, 8 Jiangwangmiao Steet, Nanjing 210042, Jiangsu, Peoples R China.;  Chen, JW (reprint author)Show the Organization-Enhanced name(s) Dalian Univ Technol, Sch Environm Sci & Technol, Linggong Rd 2, Dalian 116024, Peoples R China. ljn@nies.org;  jwchen@dlut.edu.cn
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Polybrominated Diphenyl Ethers  Thyroid-hormone-binding  Human Serum-albumin  In-vitro  Estrogen-receptor  Risk-assessment  Recombinant Transthyretin  Scientific Statement  Evolutionary Changes  Chemicals  
Molecular diversity and evolution of defensins in the manila clam Ruditapes philippinarum 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2015, 卷号: 47, 期号: 1, 页码: 302-312
作者:  Wang, Q;  Zhang, LB;  Yang, DL;  Yu, Q;  Li, F;  Cong, M;  Ji, CL;  Wu, HF;  Zhao, JM;  Zhao, JM (reprint author), Chinese Acad Sci, Key Lab Coastal Environm Processes & Ecol Remedia, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China. jmzhao@yic.ac.cn
浏览  |  Adobe PDF(1687Kb)  |  收藏  |  浏览/下载：655/278  |  提交时间：2016/04/24
Defensin  Manila Clam  Diversity  Positive Selection  
A defensin from clam Venerupis philippinarum: Molecular characterization, localization, antibacterial activity, and mechanism of action 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2015, 卷号: 51, 期号: 1, 页码: 29-38
作者:  Zhang, LB;  Yang, DL;  Wang, Q;  Yuan, ZY;  Wu, HF;  Pei, D;  Cong, M;  Li, F;  Ji, CL;  Zhao, JM;  Wu, HF (reprint author), YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
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Venerupis Philippinarum  Defensin  Molecular Characterization  Tissue Distribution  Antimicrobial Activity  Membrane Lesions  
Glutathione S-transferase (GST) gene expression profiles in two marine bivalves exposed to BDE-47 and their potential molecular mechanisms 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2015, 卷号: 33, 期号: 3, 页码: 705-713
作者:  Li Fei;  Wu Huifeng;  Wang Qing;  Li Xuehua;  Zhao Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
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Glutathione S-transferase (Gst)  Venerupis Philippinarum  Mytilus Galloprovincialis  Molecular Docking  2  Biomarker  2 '  4  4 '-tetrabromodiphenyl Ether (Bde-47)  
The interaction between organic phosphate ester and p53: An integrated experimental and in silico approach 期刊论文
MARINE POLLUTION BULLETIN, 2014, 卷号: 85, 期号: 2, 页码: 516-521
作者:  Li, Fei;  Li, Renmin;  Yang, Xianhai;  You, Liping;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, YICCAS, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
浏览  |  Adobe PDF(915Kb)  |  收藏  |  浏览/下载：635/236  |  提交时间：2015/07/31
Organophosphate Flame Retardants (Opfrs) P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Multiple Linear Regression (Mlr)