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Abnormality of mussel in the early developmental stages induced by graphene and triphenyl phosphate: In silico toxicogenomic data-mining, in vivo, and toxicity pathway-oriented approach 期刊论文
AQUATIC TOXICOLOGY, 2023, 卷号: 263, 页码: 11
作者:  Wang, Xiaoqing;  Li, Fei;  Meng, Xiangjing;  Xia, Chunlei;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：123/0  |  提交时间：2023/11/15
Plastic additives  Graphene-based nanomaterials  Toxicogenomic data mining  Combined hazards  Developmental abnormality  
Responses of microRNA in digestive glands of mussel Mytilus galloprovincialis exposed to polystyrene nanoplastics 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2023, 卷号: 249, 页码: 10
作者:  Lu, Zhen;  Wu, Sihan;  Xiao, Zeyu;  Song, Jun;  Wu, Huifeng;  Peng, Xiao
收藏  |  浏览/下载：0/0  |  提交时间：2024/05/07
Polystyrene nanoplastics (PS -NPs)  Mussel  MicroRNAs (miRNA)  Toxicological effects  Metabolism  
Critical target identification and human health risk ranking of metal ions based on mechanism-driven modeling 期刊论文
CHEMOSPHERE, 2022, 卷号: 301, 页码: 9
作者:  Wang, Xiaoqing;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng;  Li, Fei
收藏  |  浏览/下载：276/0  |  提交时间：2022/07/26
Metal ions  p53  QSAR  Genetic toxicity  Human health risk  
Ammonia nitrogen exposure caused structural damages to gill mitochondria of clam Ruditapes philippinarum 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 卷号: 222, 页码: 7
作者:  Cong, Ming;  Li, Yuanmei;  Xu, Hongchao;  Lv, Jiasen;  Wu, Huifeng;  Zhao, Ye
Adobe PDF(3140Kb)  |  收藏  |  浏览/下载：516/181  |  提交时间：2021/11/08
Ammonia nitrogen  Gill mitochondria  Swelling  MtDNA copy  Succinic dehydrogenase  Mitochondrial ultrastructure  
Tetrabromobisphenol A induced reproductive endocrine-disrupting effects in mussel Mytilus galloprovincialis 期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2021, 卷号: 416, 页码: 9
作者:  Wang, Shuang;  Ji, Chenglong;  Li, Fei;  Zhan, Junfei;  Sun, Tao;  Tang, Jianhui;  Wu, Huifeng
浏览  |  Adobe PDF(4030Kb)  |  收藏  |  浏览/下载：576/221  |  提交时间：2021/10/21
Brominated flame retardants  Marine invertebrates  Endocrine disruptor  Steroids sulfonation  
Dose-dependent responses of metabolism and tissue injuries in clam Ruditapes philippinarum after subchronic exposure to cadmium 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2021, 卷号: 779, 页码: 11
作者:  Zhan, Junfei;  Wang, Shuang;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(2610Kb)  |  收藏  |  浏览/下载：578/286  |  提交时间：2021/10/20
Cadmium  Dose-response  Hormesis  Metabolomics  Ruditapes philippinarum  Tissue injuries  
Stress responses in expressions of microRNAs in mussel Mytilus galloprovincialis exposed to cadmium 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 卷号: 212, 页码: 8
作者:  Yu, Deliang;  Peng, Zheng;  Wu, Huifeng;  Zhang, Xiaoying;  Ji, Chenglong;  Peng, Xiao
浏览  |  Adobe PDF(2857Kb)  |  收藏  |  浏览/下载：515/147  |  提交时间：2021/06/07
Mytilus galloprovincialis  MicroRNAs  Cadmium  Toxicological effects  
Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：755/295  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Global characterization of dose-dependent effects of cadmium in clam Ruditapes philippinarum 期刊论文
ENVIRONMENTAL POLLUTION, 2021, 卷号: 273, 页码: 9
作者:  Zhan, Junfei;  Wang, Shuang;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(1425Kb)  |  收藏  |  浏览/下载：600/221  |  提交时间：2021/05/22
Benchmark dose  Cadmium  Dose-dependent effects  Ruditapes philippinarum  Transcriptomics  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：414/53  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity