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Abnormality of mussel in the early developmental stages induced by graphene and triphenyl phosphate: In silico toxicogenomic data-mining, in vivo, and toxicity pathway-oriented approach 期刊论文
AQUATIC TOXICOLOGY, 2023, 卷号: 263, 页码: 11
作者:  Wang, Xiaoqing;  Li, Fei;  Meng, Xiangjing;  Xia, Chunlei;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：165/0  |  提交时间：2023/11/15
Plastic additives  Graphene-based nanomaterials  Toxicogenomic data mining  Combined hazards  Developmental abnormality  
Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：809/311  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Liver transcriptome analysis reveals the molecular responses to low-salinity in large yellow croaker Larimichthys crocea 期刊论文
AQUACULTURE, 2020, 卷号: 517, 页码: UNSP 734827
作者:  Lu, Z;  Huang, WQ;  Wang, S;  Shan, XJ;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(1875Kb)  |  收藏  |  浏览/下载：399/62  |  提交时间：2020/07/08
Larimichthys crocea  Transcriptome  Low salinity  Molecular response  
Toxicological effects of As (V) in juvenile rockfish Sebastes schlegelii by a combined metabolomic and proteomic approach 期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: 255, 期号: 2, 页码: 113333
作者:  Xu, LL;  Lu, Z;  Ji, CL;  Cong, M;  Li, F;  Shan, XJ;  Wu, HF
浏览  |  Adobe PDF(1885Kb)  |  收藏  |  浏览/下载：616/312  |  提交时间：2020/07/08
Arsenic  Toxicological effect  Juvenile rockfish  Proteomics  Metabolomics  
Combinatorial immune and stress response, cytoskeleton and signal transduction effects of graphene and triphenyl phosphate (TPP) in mussel Mytilus galloprovincialis 期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2019, 卷号: 378, 页码: UNSP 120778
作者:  Meng, XJ;  Li, F;  Wang, XQ;  Liu, JL;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(1686Kb)  |  收藏  |  浏览/下载：690/341  |  提交时间：2020/07/08
Joint effects  Graphene  Triphenyl phosphate (TPP)  Toxicity  Mussel  
Individual and Combined Toxicities of Benzo[a]pyrene and 2,2',4,4'-Tetrabromodiphenyl Ether on Early Life Stages of the Pacific Oyster, Crassostrea gigas 期刊论文
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2017, 卷号: 99, 期号: 5, 页码: 582-588
作者:  Xie, Jia;  Yang, Dinglong;  Sun, Xiyan;  Cao, Ruiwen;  Chen, Lizhu;  Wang, Qing;  Li, Fei;  Wu, Huifeng;  Ji, Chenglong;  Cong, Ming;  Zhao, Jianmin;  Wang, Qing(Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China);  Zhao, Jianmin(Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China)
收藏  |  浏览/下载：519/0  |  提交时间：2018/03/14
Embryotoxicity  Larval Mortality  Genotoxicity  Bap  Bde-47  Combined Toxicity  
Individual and Combined Toxicities of Benzo[a]pyrene and 2,2',4,4'-Tetrabromodiphenyl Ether on Early Life Stages of the Pacific Oyster, Crassostrea gigas 期刊论文
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2017, 卷号: 99, 期号: 5, 页码: 582-588
作者:  Xie, J;  Yang, DL;  Sun, XY;  Cao, RW;  Chen, LZ;  Wang, Q;  Li, F;  Wu, HF;  Ji, CL;  Cong, M;  Zhao, JM
Adobe PDF(1526Kb)  |  收藏  |  浏览/下载：392/23  |  提交时间：2020/07/08
Embryotoxicity  Larval mortality  Genotoxicity  BaP  BDE-47  Combined toxicity  
Effects of hypoxia in the gills of the Manila clam Ruditapes philippinarum using NMR-based metabolomics 期刊论文
MARINE POLLUTION BULLETIN, 2017, 卷号: 114, 期号: 1, 页码: 84-89
作者:  Zhang, Ying;  Wu, Huifeng;  Wei, Lei;  Xie, Zeping;  Guan, Bo;  Zhang, Y (reprint author), Binzhou Med Univ, Sch Basic Med Sci, 346,Guanhai Rd, Yantai 264003, Peoples R China. zhangying@bzmc.edu.cn
浏览  |  Adobe PDF(1049Kb)  |  收藏  |  浏览/下载：779/357  |  提交时间：2017/04/06
Metabolic Profile  Hypoxia  Ruditapes Philippinarum  Proton Nuclear Magnetic Resonance  Metabolomics  
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(2093Kb)  |  收藏  |  浏览/下载：863/303  |  提交时间：2015/07/31
Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)  
Towards a System Level Understanding of Non-Model Organisms Sampled from the Environment: A Network Biology Approach 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2011, 卷号: 7, 期号: 8, 页码: e1002126
作者:  Williams, Tim D.;  Turan, Nil;  Diab, Amer M.;  Wu, Huifeng;  Mackenzie, Carolynn;  Bartie, Katie L.;  Hrydziuszko, Olga;  Lyons, Brett P.;  Stentiford, Grant D.;  Herbert, John M.;  Abraham, Joseph K.;  Katsiadaki, Ioanna;  Leaver, Michael J.;  Taggart, John B.;  George, Stephen G.;  Viant, Mark R.;  Chipman, Kevin J.;  Falciani, Francesco
浏览  |  Adobe PDF(1348Kb)  |  收藏  |  浏览/下载：1157/248  |  提交时间：2011/11/11
Flounder Platichthys-flesus  Histopathological Biomarkers  Pleuronectes-platessa  Endocrine Disruption  Gene-expression  Liver Fibrosis  Marine Fish  Receptor  Microarray  Proteasome