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Seawater acidification aggravated cadmium toxicity in the oyster Crassostrea gigas: Metal bioaccumulation, subcellular distribution and multiple physiological responses 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 642, 页码: 809-823
作者:  Cao, Ruiwen;  Liu, Yongliang;  Wang, Qing;  Dong, Zhijun;  Yang, Dinglong;  Liu, Hui;  Ran, Wen;  Qu, Yi;  Zhao, Jianmin
Adobe PDF(3991Kb)  |  收藏  |  浏览/下载：458/115  |  提交时间：2020/07/08
Ocean acidification  Cadmium  Crassostrea gigas  Physiological response  Apoptosis  Bioconcentration  
Metabolite and gene expression responses in juvenile flounder Paralichthys olivaceus exposed to reduced salinities 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 63, 页码: 417-423
作者:  Wu, Huifeng;  Liu, Jialin;  Lu, Zhen;  Xu, Lanlan;  Ji, Chenglong;  Wang, Qing;  Zhao, Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
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Salinity  Biological Effects  Paralichthys Olivaceus  Metabolite  Gene Expression  
Proteomic responses reveal the differential effects induced by cadmium in mussels Mytilus galloprovincialis at early life stages 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2016, 卷号: 55, 页码: 510-515
作者:  Xu, LL;  Peng, X;  Yu, DL;  Ji, CL;  Zhao, JM;  Wu, HF;  Ji, CL (reprint author), Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. Email:clji@yic.ac.cn
浏览  |  Adobe PDF(760Kb)  |  收藏  |  浏览/下载：768/372  |  提交时间：2016/11/30
Mytilus Galloprovincialis  Cadmium  Biological Effects  Proteomics  
Multiple biomarkers of the cytotoxicity induced by BDE-47 in human embryonic kidney cells 期刊论文
CHEMOSPHERE, 2015, 卷号: 126, 页码: 32-39
作者:  Wu, Huifeng;  Cao, Lulu;  Li, Fei;  Lian, Peiwen;  Zhao, Jianmin;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn
浏览  |  Adobe PDF(765Kb)  |  收藏  |  浏览/下载：916/386  |  提交时间：2015/07/31
Bde-47  Hek293 Cells  Cytotoxicity  Cell Apoptosis  Ros  Metabolomics  
Glutathione S-transferase (GST) gene expression profiles in two marine bivalves exposed to BDE-47 and their potential molecular mechanisms 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2015, 卷号: 33, 期号: 3, 页码: 705-713
作者:  Li Fei;  Wu Huifeng;  Wang Qing;  Li Xuehua;  Zhao Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(580Kb)  |  收藏  |  浏览/下载：892/299  |  提交时间：2015/07/31
Glutathione S-transferase (Gst)  Venerupis Philippinarum  Mytilus Galloprovincialis  Molecular Docking  2  Biomarker  2 '  4  4 '-tetrabromodiphenyl Ether (Bde-47)  
BDE-47对人胚肾细胞HEK293的毒理效应及作用机制 期刊论文
生态毒理学报, 2015, 卷号: ., 期号: 2, 页码: 236-242
作者:  曹璐璐;  李斐;  吴惠丰;  赵建民
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2,2’,4,4’-四溴联苯醚（BDE-47）  人胚肾细胞  细胞凋亡  氧化损伤  p53  Bax  
Identification and mRNA expression of two 17 beta-hydroxysteroid dehydrogenase genes in the marine mussel Mytilus galloprovincialis following exposure to endocrine disrupting chemicals 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2014, 卷号: 37, 期号: 3, 页码: 1243-1255
作者:  Zhang, Yingying;  Wang, Qing;  Ji, Yinglu;  Zhang, Qian;  Wu, Huifeng;  Xie, Jia;  Zhao, Jianmin;  Zhao, JM (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Zone Environm Proc & Ecol Re, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
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17 Beta-hydroxysteroid  Dehydrogenases  Mytilus Galloprovincialis  Digestive Glands  Endocrine Disrupting Chemicals  Gene Expression  
菲律宾蛤仔(Venerupis philippinarum)Rho 型GST和微粒体型GST 的序列分析及表达特征研究 期刊论文
海洋与湖沼, 2014, 卷号: 45, 期号: 4, 页码: 798-805
作者:  章盈盈;  袁泽轶;  王清;  李巧梅;  吴惠丰;  赵建民
Adobe PDF(1172Kb)  |  收藏  |  浏览/下载：646/159  |  提交时间：2015/07/30
谷胱甘肽硫转移酶  菲律宾蛤仔  基因克隆  基因表达  
Proteomic and metabolomic responses in hepatopancreas of Mytilus galloprovincialis challenged by Micrococcus luteus and Vibrio anguillarum 期刊论文
JOURNAL OF PROTEOMICS, 2013, 卷号: 94, 页码: 54-67
作者:  Wu, Huifeng;  Ji, Chenglong;  Wei, Lei;  Zhao, Jianmin;  Lu, Hongjian
浏览  |  Adobe PDF(1059Kb)  |  收藏  |  浏览/下载：1388/529  |  提交时间：2014/07/08
Proteomics  Metabolomics  Mytilus Galloprovincialis  Bacteria  
Metabolomic analysis revealed the differential responses in two pedigrees of clam Ruditapes philippinarum towards Vibrio harveyi challenge 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2013, 卷号: 35, 期号: 6, 页码: 1969-1975
作者:  Liu, Xiaoli;  Zhao, Jianmin;  Wu, Huifeng;  Wang, Qing
Adobe PDF(807Kb)  |  收藏  |  浏览/下载：902/207  |  提交时间：2014/07/08
Metabolomics  Ruditapes Philippinarum  Pedigree  Vibrio Harveyi  Hepatopancreas