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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：809/311  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Effects of hypoxia in the gills of the Manila clam Ruditapes philippinarum using NMR-based metabolomics 期刊论文
MARINE POLLUTION BULLETIN, 2017, 卷号: 114, 期号: 1, 页码: 84-89
作者:  Zhang, Ying;  Wu, Huifeng;  Wei, Lei;  Xie, Zeping;  Guan, Bo;  Zhang, Y (reprint author), Binzhou Med Univ, Sch Basic Med Sci, 346,Guanhai Rd, Yantai 264003, Peoples R China. zhangying@bzmc.edu.cn
浏览  |  Adobe PDF(1049Kb)  |  收藏  |  浏览/下载：779/357  |  提交时间：2017/04/06
Metabolic Profile  Hypoxia  Ruditapes Philippinarum  Proton Nuclear Magnetic Resonance  Metabolomics  
Effects of ocean acidification on immune responses of the Pacific oyster Crassostrea gigas 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2016, 卷号: 49, 页码: 24-33
作者:  Wang, Q;  Cao, RW;  Ning, XX;  You, LP;  Mu, CK;  Wang, CL;  Wei, L;  Cong, M;  Wu, HF;  Zhao, JM;  Zhao, JM (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. jmzhao@yic.ac.cn
浏览  |  Adobe PDF(1523Kb)  |  收藏  |  浏览/下载：1007/493  |  提交时间：2016/05/24
Ocean Acidification  Pco(2)  Oyster  Immune Response  Antioxidant Enzyme  
Combined metabolome and proteome analysis of the mantle tissue from Pacific oyster Crassostrea gigas exposed to elevated pCO(2) 期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS, 2015, 卷号: 13, 页码: 16-23
作者:  Wei, Lei;  Wang, Qing;  Ning, Xuanxuan;  Mu, Changkao;  Wang, Chunlin;  Cao, Ruiwen;  Wu, Huifeng;  Cong, Ming;  Li, Fei;  Ji, Chenglong;  Zhao, Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
浏览  |  Adobe PDF(588Kb)  |  收藏  |  浏览/下载：1031/440  |  提交时间：2015/07/31
Ocean Acidification  Proteomics  Metabolomics  Crassostrea Gigas  
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
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Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)  
Proteomic and metabolomic responses of Pacific oyster Crassostrea gigas to elevated pCO(2) exposure 期刊论文
JOURNAL OF PROTEOMICS, 2015, 卷号: 112, 页码: 83-94
作者:  Wei, Lei;  Wang, Qing;  Wu, Huifeng;  Ji, Chenglong;  Zhao, Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, YICCAS, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc,Shandong Prov, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
Adobe PDF(63Kb)  |  收藏  |  浏览/下载：941/458  |  提交时间：2015/07/31
Ocean Acidification  Proteomics  Metabolomics  Oyster  Crassostrea Gigas  
Influences of anthropogenic cultivation on C, N and P stoichiometry of reed-dominated coastal wetlands in the Yellow River Delta 期刊论文
GEODERMA, 2014, 卷号: 235, 页码: 227-232
作者:  Qu, Fanzhu;  Yu, Junbao;  Du, Siyao;  Li, Yunzhao;  Lv, Xiaofei;  Ning, Kai;  Wu, Huifeng;  Meng, Ling;  Yu, JB (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Environm Proc, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Peoples R China. junbao.yu@gmail.com
浏览  |  Adobe PDF(629Kb)  |  收藏  |  浏览/下载：904/423  |  提交时间：2015/07/31
Anthropogenic Cultivation  c  Coastal Wetland  n And p Stoichiometry  The Yellow River Delta  
Determination and Prediction of the Binding Interaction between Organophosphate Flame Retardants and p53 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2014, 卷号: 27, 期号: 11, 页码: 1918-1925
作者:  Li, Fei;  Yang, Xianhai;  Li, Xuehua;  Li, Renmin;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
浏览  |  Adobe PDF(1104Kb)  |  收藏  |  浏览/下载：908/407  |  提交时间：2015/07/31
Polybrominated Diphenyl Ethers  Thyroid-hormone Receptors  Structural Requirements  Surface Waters  In-silico  Plasticizers  Complex  Air  Regression  Zebrafish  
Soil acidification increases metal extractability and bioavailability in old orchard soils of Northeast Jiaodong Peninsula in China 期刊论文
ENVIRONMENTAL POLLUTION, 2014, 卷号: 188, 页码: 144-152
作者:  Li, Lianzhen;  Wu, Huifeng;  van Gestel, Cornelis A. M.;  Peijnenburg, Willie J. G. M.;  Allen, Herbert E.;  van Gestel, CAM (reprint author), Vrije Univ Amsterdam, Dept Ecol Sci, Fac Earth & Life Sci, De Boelelaan 1085, NL-1081 HV Amsterdam, Netherlands. hfwu@yic.a.cn
浏览  |  Adobe PDF(552Kb)  |  收藏  |  浏览/下载：794/362  |  提交时间：2015/07/31
Soil Acidification  Orchard  Vineyard  Metal Bioavailability  Earthworm  
Proteomic and metabolomic responses in hepatopancreas of Mytilus galloprovincialis challenged by Micrococcus luteus and Vibrio anguillarum 期刊论文
JOURNAL OF PROTEOMICS, 2013, 卷号: 94, 页码: 54-67
作者:  Wu, Huifeng;  Ji, Chenglong;  Wei, Lei;  Zhao, Jianmin;  Lu, Hongjian
浏览  |  Adobe PDF(1059Kb)  |  收藏  |  浏览/下载：1415/539  |  提交时间：2014/07/08
Proteomics  Metabolomics  Mytilus Galloprovincialis  Bacteria