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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：713/291  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：387/53  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
Toxicological effects of graphene on mussel Mytilus galloprovincialis hemocytes after individual and combined exposure with triphenyl phosphate 期刊论文
MARINE POLLUTION BULLETIN, 2020, 卷号: 151, 页码: 110838
作者:  Meng, Xiangjing;  Li, Fei;  Wang, Xiaoqing;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(2503Kb)  |  收藏  |  浏览/下载：685/297  |  提交时间：2020/07/08
ORGANOPHOSPHATE FLAME RETARDANTS  IN-VITRO  PRISTINE GRAPHENE  OXIDATIVE STRESS  MARINE MUSSEL  CAGED MUSSELS  OXIDE  TOXICITY  NANOPARTICLES  NANOMATERIALS  
iTRAQ-based proteomic analysis on the mitochondrial responses in gill tissues of juvenile olive flounder Paralichthys olivaceus exposed to cadmium 期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 257, 页码: 113591
作者:  Lu, Z;  Wang, S;  Ji, CL;  Li, F;  Cong, M;  Shan, XJ;  Wu, HF
浏览  |  Adobe PDF(2097Kb)  |  收藏  |  浏览/下载：725/378  |  提交时间：2020/07/08
Cadmium  Paralichthys olivaceus  iTRAQ  Proteomics  Mitochondrial toxicity  
石墨烯纳米材料的生物安全性研究进展 期刊论文
鲁东大学学报(自然科学版), 2020, 卷号: 36, 期号: 01, 页码: 60-70
作者:  马丽娟;  张明兴;  李斐;  吴惠丰;  赵建民
Adobe PDF(703Kb)  |  收藏  |  浏览/下载：189/38  |  提交时间：2021/12/01
石墨烯  生物毒性  纳米材料  生物安全性  
Combinatorial immune and stress response, cytoskeleton and signal transduction effects of graphene and triphenyl phosphate (TPP) in mussel Mytilus galloprovincialis 期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2019, 卷号: 378, 页码: UNSP 120778
作者:  Meng, XJ;  Li, F;  Wang, XQ;  Liu, JL;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(1686Kb)  |  收藏  |  浏览/下载：591/311  |  提交时间：2020/07/08
Joint effects  Graphene  Triphenyl phosphate (TPP)  Toxicity  Mussel  
The role of GST omega in metabolism and detoxification of arsenic in clam Ruditapes philippinarum 期刊论文
AQUATIC TOXICOLOGY, 2018, 卷号: 204, 页码: 9-18
作者:  Chen, Lizhu;  Wu, Huifeng;  Zhao, Jianmin;  Zhang, Wei;  Zhang, Li;  Sun, Shan;  Yang, Dinglong;  Cheng, Bo;  Wang, Qing
浏览  |  Adobe PDF(1921Kb)  |  收藏  |  浏览/下载：462/278  |  提交时间：2020/07/08
Arsenic  Bioaccumulation  Metabolism  Subcellular distribution  Glutathione S-transferase omega  
Proteomic responses reveal the differential effects induced by cadmium in mussels Mytilus galloprovincialis at early life stages 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2016, 卷号: 55, 页码: 510-515
作者:  Xu, LL;  Peng, X;  Yu, DL;  Ji, CL;  Zhao, JM;  Wu, HF;  Ji, CL (reprint author), Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. Email:clji@yic.ac.cn
浏览  |  Adobe PDF(760Kb)  |  收藏  |  浏览/下载：719/357  |  提交时间：2016/11/30
Mytilus Galloprovincialis  Cadmium  Biological Effects  Proteomics  
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(2093Kb)  |  收藏  |  浏览/下载：804/289  |  提交时间：2015/07/31
Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)  
Proteomic and metabolomic analysis of earthworm Eisenia fetida exposed to different concentrations of 2,2 ',4,4 '-tetrabromodiphenyl ether 期刊论文
JOURNAL OF PROTEOMICS, 2013, 卷号: 91, 页码: 405-416
作者:  Ji, Chenglong;  Wu, Huifeng;  Wei, Lei;  Zhao, Jianmin;  Lu, Hongjian;  Yu, Junbao
浏览  |  Adobe PDF(1511Kb)  |  收藏  |  浏览/下载：1072/299  |  提交时间：2014/07/08
Proteomics  Metabolomics  Eisenia Fetida  Bde 47