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Critical target identification and human health risk ranking of metal ions based on mechanism-driven modeling 期刊论文
CHEMOSPHERE, 2022, 卷号: 301, 页码: 9
作者:  Wang, Xiaoqing;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng;  Li, Fei
收藏  |  浏览/下载:257/0  |  提交时间:2022/07/26
Metal ions  p53  QSAR  Genetic toxicity  Human health risk  
大数据挖掘和机器学习在毒理学中的应用 期刊论文
生态毒理学报, 2022, 卷号: 17, 期号: 1, 页码: 93-101
作者:  滕跃发;  王晓晴;  李斐;  吴惠丰;  吉成龙;  于进福
收藏  |  浏览/下载:18/0  |  提交时间:2024/01/26
数据挖掘  机器学习  结构-活性关系  AOP  计算毒理学  
Global characterization of dose-dependent effects of cadmium in clam Ruditapes philippinarum 期刊论文
ENVIRONMENTAL POLLUTION, 2021, 卷号: 273, 页码: 9
作者:  Zhan, Junfei;  Wang, Shuang;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
Adobe PDF(1425Kb)  |  收藏  |  浏览/下载:574/217  |  提交时间:2021/05/22
Benchmark dose  Cadmium  Dose-dependent effects  Ruditapes philippinarum  Transcriptomics  
Combinatorial immune and stress response, cytoskeleton and signal transduction effects of graphene and triphenyl phosphate (TPP) in mussel Mytilus galloprovincialis 期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2019, 卷号: 378, 页码: UNSP 120778
作者:  Meng, XJ;  Li, F;  Wang, XQ;  Liu, JL;  Ji, CL;  Wu, HF
Adobe PDF(1686Kb)  |  收藏  |  浏览/下载:596/313  |  提交时间:2020/07/08
Joint effects  Graphene  Triphenyl phosphate (TPP)  Toxicity  Mussel  
Evaluation of mitochondrial toxicity of cadmium in clam Ruditapes philippinarum using iTRAQ-based proteomics 期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: 251, 页码: 802-810
作者:  Ji, CL;  Lu, Z;  Xu, LL;  Li, F;  Cong, M;  Shan, XJ;  Wu, HF
Adobe PDF(1493Kb)  |  收藏  |  浏览/下载:519/287  |  提交时间:2020/07/08
Cadmium  iTRAQ  Proteomics  Mitochondrial toxicity  Ruditapes philippinarum  
The critical factors affecting typical organophosphate flame retardants to mimetic biomembrane: An integrated in vitro and in silico study 期刊论文
CHEMOSPHERE, 2019, 卷号: 226, 页码: 159-165
作者:  Wang, XQ;  Meng, XJ;  Li, F;  Ding, JW;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(969Kb)  |  收藏  |  浏览/下载:497/209  |  提交时间:2020/07/08
Organophosphate flame retardants (OPFRs)  Quantitative structure-activity relationship (QSAR)  Mimetic biomembrane  Electrochemical impedance spectroscopy (EIS)  Partial least squares (PLS)  
评估和预测有机磷酸酯阻燃剂对模拟生物膜损伤的方法 专利
专利号: 2018110946395, 申请日期: 2018-12-21,
发明人:  王晓晴;  李斐;  刘佳琳;  吴惠丰;  吉成龙
收藏  |  浏览/下载:10/0  |  提交时间:2024/01/26
Interaction between organic phosphate ester and p53: An integrated experimental and in silico approach 期刊论文
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 卷号: 255
作者:  Li, Fei
浏览  |  Adobe PDF(915Kb)  |  收藏  |  浏览/下载:275/135  |  提交时间:2020/07/08
Rational Selection of the 3D Structure of Biomacromolecules for Molecular Docking Studies on the Mechanism of Endocrine Disruptor Action 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 卷号: 29, 期号: 9, 页码: 1565-1570
作者:  Yang, Xianhai;  Liu, Huihui;  Liu, Jining;  Li, Fei;  Li, Xuehua;  Shi, Lili;  Chen, Jingwen;  Liu, JB (reprint author) Minist Environm Protect, Nanjing Inst Environm Sci, 8 Jiangwangmiao Steet, Nanjing 210042, Jiangsu, Peoples R China.;  Chen, JW (reprint author)Show the Organization-Enhanced name(s) Dalian Univ Technol, Sch Environm Sci & Technol, Linggong Rd 2, Dalian 116024, Peoples R China. ljn@nies.org;  jwchen@dlut.edu.cn
浏览  |  Adobe PDF(2663Kb)  |  收藏  |  浏览/下载:696/301  |  提交时间:2016/11/30
Polybrominated Diphenyl Ethers  Thyroid-hormone-binding  Human Serum-albumin  In-vitro  Estrogen-receptor  Risk-assessment  Recombinant Transthyretin  Scientific Statement  Evolutionary Changes  Chemicals  
Molecular diversity and evolution of defensins in the manila clam Ruditapes philippinarum 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2015, 卷号: 47, 期号: 1, 页码: 302-312
作者:  Wang, Q;  Zhang, LB;  Yang, DL;  Yu, Q;  Li, F;  Cong, M;  Ji, CL;  Wu, HF;  Zhao, JM;  Zhao, JM (reprint author), Chinese Acad Sci, Key Lab Coastal Environm Processes & Ecol Remedia, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China. jmzhao@yic.ac.cn
浏览  |  Adobe PDF(1687Kb)  |  收藏  |  浏览/下载:629/275  |  提交时间:2016/04/24
Defensin  Manila Clam  Diversity  Positive Selection