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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：730/293  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Global characterization of dose-dependent effects of cadmium in clam Ruditapes philippinarum 期刊论文
ENVIRONMENTAL POLLUTION, 2021, 卷号: 273, 页码: 9
作者:  Zhan, Junfei;  Wang, Shuang;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(1425Kb)  |  收藏  |  浏览/下载：581/218  |  提交时间：2021/05/22
Benchmark dose  Cadmium  Dose-dependent effects  Ruditapes philippinarum  Transcriptomics  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：400/53  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
Profiling of microRNAs and mRNAs in marine mussel Mytilus galloprovincialis 期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2020, 卷号: 230, 页码: 108697
作者:  Yu, Deliang;  Wu, Huifeng;  Peng, Xiao;  Ji, Chenglong;  Zhang, Xiaoying;  Song, Jun;  Qu, Junle
浏览  |  Adobe PDF(1152Kb)  |  收藏  |  浏览/下载：697/294  |  提交时间：2020/07/08
CUCUMBER APOSTICHOPUS-JAPONICUS  OYSTER OSTREA-EDULIS  METABOLOMIC ANALYSIS  OXIDATIVE STRESS  DIGESTIVE GLAND  LET-7  EXPRESSION  MIRNAS  IDENTIFICATION  DROSOPHILA  
Liver transcriptome analysis reveals the molecular responses to low-salinity in large yellow croaker Larimichthys crocea 期刊论文
AQUACULTURE, 2020, 卷号: 517, 页码: UNSP 734827
作者:  Lu, Z;  Huang, WQ;  Wang, S;  Shan, XJ;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(1875Kb)  |  收藏  |  浏览/下载：366/62  |  提交时间：2020/07/08
Larimichthys crocea  Transcriptome  Low salinity  Molecular response  
iTRAQ-based proteomic analysis on the mitochondrial responses in gill tissues of juvenile olive flounder Paralichthys olivaceus exposed to cadmium 期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 257, 页码: 113591
作者:  Lu, Z;  Wang, S;  Ji, CL;  Li, F;  Cong, M;  Shan, XJ;  Wu, HF
浏览  |  Adobe PDF(2097Kb)  |  收藏  |  浏览/下载：727/379  |  提交时间：2020/07/08
Cadmium  Paralichthys olivaceus  iTRAQ  Proteomics  Mitochondrial toxicity  
Digital gene expression analysis in the gills of Ruditapes philippinarum after nitrite exposure 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 184, 页码: 7
作者:  Lv, Jiasen;  Cao, Tengfei;  Ji, Chenglong;  Cong, Ming;  Zhao, Jianmin;  Wu, Huifeng
浏览  |  Adobe PDF(594Kb)  |  收藏  |  浏览/下载：456/187  |  提交时间：2021/06/22
Digital gene expression  Gills  Ruditapes philippinarum  Nitrite  
The critical factors affecting typical organophosphate flame retardants to mimetic biomembrane: An integrated in vitro and in silico study 期刊论文
CHEMOSPHERE, 2019, 卷号: 226, 页码: 159-165
作者:  Wang, XQ;  Meng, XJ;  Li, F;  Ding, JW;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(969Kb)  |  收藏  |  浏览/下载：504/209  |  提交时间：2020/07/08
Organophosphate flame retardants (OPFRs)  Quantitative structure-activity relationship (QSAR)  Mimetic biomembrane  Electrochemical impedance spectroscopy (EIS)  Partial least squares (PLS)  
A comparative proteomic study on the effects of metal pollution in oysters Crassostrea hongkongensis 期刊论文
MARINE POLLUTION BULLETIN, 2016, 卷号: 112, 期号: 1-2, 页码: 436-442
作者:  Xu, LL;  Ji, CL;  Wu, HF;  Tan, QG;  Wang, WX;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Peoples R China. Email:hfwu@yic.ac.cn
浏览  |  Adobe PDF(1068Kb)  |  收藏  |  浏览/下载：725/316  |  提交时间：2016/12/18
Metal Pollution  Crassostrea Hongkongensis  Hepatopancreas  Proteomics  
Homologous cloning, characterization and expression of a new halophyte phytochelatin synthase gene in Suaeda salsa 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2016, 卷号: 34, 期号: 5, 页码: 1034-1043
作者:  Cong, M;  Zhao, JM;  Lu, JS;  Ren, ZM;  Wu, HF;  Wu, HF (reprint author), Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(435Kb)  |  收藏  |  浏览/下载：678/308  |  提交时间：2016/10/08
Suaeda Salsa  Halophyte  Phytochelatin Synthase (Pcs)  Homologous Cloning  Heavy Metal  Tissue Distribution