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Toxicity pathways of lipid metabolic disorders induced by typical replacement flame retardants via data-driven analysis, in silico and in vitro approaches 期刊论文
CHEMOSPHERE, 2022, 卷号: 287, 页码: 9
作者:  Wang, Xiaoqing;  Wang, Li;  Li, Fei;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：236/0  |  提交时间：2022/06/16
Toxicity pathways  Lipid metabolism disorder  Bibliometric analysis  Computational toxicology  Data-driven analysis  
Effect of microplastics on aquatic biota: A hormetic perspective 期刊论文
ENVIRONMENTAL POLLUTION, 2021, 卷号: 285, 页码: 10
作者:  Sun, Tao;  Zhan, Junfei;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
Adobe PDF(4998Kb)  |  收藏  |  浏览/下载：674/221  |  提交时间：2021/10/21
Plastic pollution  Aquatic environment  Dose response  Risk assessment  Environmentally relevant concentrations  
Tetrabromobisphenol A induced reproductive endocrine-disrupting effects in mussel Mytilus galloprovincialis 期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2021, 卷号: 416, 页码: 9
作者:  Wang, Shuang;  Ji, Chenglong;  Li, Fei;  Zhan, Junfei;  Sun, Tao;  Tang, Jianhui;  Wu, Huifeng
Adobe PDF(4030Kb)  |  收藏  |  浏览/下载：543/218  |  提交时间：2021/10/21
Brominated flame retardants  Marine invertebrates  Endocrine disruptor  Steroids sulfonation  
Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：717/292  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：389/53  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
Toxicological effects of graphene on mussel Mytilus galloprovincialis hemocytes after individual and combined exposure with triphenyl phosphate 期刊论文
MARINE POLLUTION BULLETIN, 2020, 卷号: 151, 页码: 110838
作者:  Meng, Xiangjing;  Li, Fei;  Wang, Xiaoqing;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
Adobe PDF(2503Kb)  |  收藏  |  浏览/下载：686/297  |  提交时间：2020/07/08
ORGANOPHOSPHATE FLAME RETARDANTS  IN-VITRO  PRISTINE GRAPHENE  OXIDATIVE STRESS  MARINE MUSSEL  CAGED MUSSELS  OXIDE  TOXICITY  NANOPARTICLES  NANOMATERIALS  
Combinatorial immune and stress response, cytoskeleton and signal transduction effects of graphene and triphenyl phosphate (TPP) in mussel Mytilus galloprovincialis 期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2019, 卷号: 378, 页码: UNSP 120778
作者:  Meng, XJ;  Li, F;  Wang, XQ;  Liu, JL;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(1686Kb)  |  收藏  |  浏览/下载：595/313  |  提交时间：2020/07/08
Joint effects  Graphene  Triphenyl phosphate (TPP)  Toxicity  Mussel  
The critical factors affecting typical organophosphate flame retardants to mimetic biomembrane: An integrated in vitro and in silico study 期刊论文
CHEMOSPHERE, 2019, 卷号: 226, 页码: 159-165
作者:  Wang, XQ;  Meng, XJ;  Li, F;  Ding, JW;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(969Kb)  |  收藏  |  浏览/下载：494/209  |  提交时间：2020/07/08
Organophosphate flame retardants (OPFRs)  Quantitative structure-activity relationship (QSAR)  Mimetic biomembrane  Electrochemical impedance spectroscopy (EIS)  Partial least squares (PLS)  
Individual and Combined Toxicities of Benzo[a]pyrene and 2,2',4,4'-Tetrabromodiphenyl Ether on Early Life Stages of the Pacific Oyster, Crassostrea gigas 期刊论文
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2017, 卷号: 99, 期号: 5, 页码: 582-588
作者:  Xie, J;  Yang, DL;  Sun, XY;  Cao, RW;  Chen, LZ;  Wang, Q;  Li, F;  Wu, HF;  Ji, CL;  Cong, M;  Zhao, JM
Adobe PDF(1526Kb)  |  收藏  |  浏览/下载：338/23  |  提交时间：2020/07/08
Embryotoxicity  Larval mortality  Genotoxicity  BaP  BDE-47  Combined toxicity  
Rational Selection of the 3D Structure of Biomacromolecules for Molecular Docking Studies on the Mechanism of Endocrine Disruptor Action 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 卷号: 29, 期号: 9, 页码: 1565-1570
作者:  Yang, Xianhai;  Liu, Huihui;  Liu, Jining;  Li, Fei;  Li, Xuehua;  Shi, Lili;  Chen, Jingwen;  Liu, JB (reprint author) Minist Environm Protect, Nanjing Inst Environm Sci, 8 Jiangwangmiao Steet, Nanjing 210042, Jiangsu, Peoples R China.;  Chen, JW (reprint author)Show the Organization-Enhanced name(s) Dalian Univ Technol, Sch Environm Sci & Technol, Linggong Rd 2, Dalian 116024, Peoples R China. ljn@nies.org;  jwchen@dlut.edu.cn
Adobe PDF(2663Kb)  |  收藏  |  浏览/下载：693/301  |  提交时间：2016/11/30
Polybrominated Diphenyl Ethers  Thyroid-hormone-binding  Human Serum-albumin  In-vitro  Estrogen-receptor  Risk-assessment  Recombinant Transthyretin  Scientific Statement  Evolutionary Changes  Chemicals