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具槽帕拉藻代谢组提取方法的比较研究 期刊论文
海洋通报, 2015, 卷号: 34, 期号: 6, 页码: 703-709
作者:  于倩;  王清;  韩伟;  张倩;  吴惠丰;  赵建民;  赵建民,中国科学院烟台海岸带研究所中国科学院海岸带环境过程与生态修复重点实验室,Email：jmzhao@yic.ac.cn;  吴惠丰,中国科学院烟台海岸带研究所中国科学院海岸带环境过程与生态修复重点实验室,Email：hfwu@yic.ac.cn
Adobe PDF(744Kb)  |  收藏  |  浏览/下载：786/330  |  提交时间：2016/12/15
代谢组学  代谢物提取  Nmr  具槽帕拉藻(Paralia Sulate)  
Comparative investigations on the biological effects of As (III) and As (V) in clam Ruditapes philippinarum using multiple biomarkers 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2015, 卷号: 47, 期号: 1, 页码: 79-84
作者:  Ji, CL;  Xu, H;  Wang, Q;  Zhao, JM;  Wu, HF;  Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
Adobe PDF(756Kb)  |  收藏  |  浏览/下载：596/264  |  提交时间：2016/04/24
Ruditapes Philippinarum  Arsenic  Biological Effects  Metabolomics  
A metabolomic study on the responses of daphnia magna exposed to silver nitrate and coated silver nanoparticles 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2015, 卷号: 119, 页码: 66-73
作者:  Li, LZ;  Wu, HF;  Ji, CL;  van Gestel, CAM;  Allen, HE;  Peijnenburg, WJGM;  Wu, HF (reprint author), Chinese Acad Sci, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Environm Proc,YICCA, 17,Chunhui Rd, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
Adobe PDF(1703Kb)  |  收藏  |  浏览/下载：715/310  |  提交时间：2016/06/05
Daphnia Magna  Silver Nanoparticle  Metabolomics  Silver Ion  Sublethal Toxicity  
典型持久性有机污染物与抑癌基因相互作用的分子模拟与验证 期刊论文
科学通报, 2015, 卷号: 60, 期号: 19, 页码: 1804-1809
作者:  吴惠丰;  曹璐璐;  李斐;  李雪花;  赵建民
Adobe PDF(1577Kb)  |  收藏  |  浏览/下载：710/316  |  提交时间：2016/12/15
持久性有机污染物  P53  2  分子模拟  2'  光谱法  4  4'-四溴联苯醚(Bde-47)  
Multiple biomarkers of biological effects induced by cadmium in clam Ruditapes philippinarum 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2015, 卷号: 44, 期号: 2, 页码: 430-435
作者:  Ji, CL;  Wu, HF;  Zhou, M;  Zhao, JM;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
Adobe PDF(707Kb)  |  收藏  |  浏览/下载：690/247  |  提交时间：2015/07/31
Ruditapes Philippinarum  Cadmium  Biological Effects  Metabolomics  
The relations between metabolic variations and genetic evolution of different species 期刊论文
ANALYTICAL BIOCHEMISTRY, 2015, 卷号: 477, 页码: 105-114
作者:  Li, Zhishui;  Lin, Chenghong;  Xu, Jingjing;  Wu, Huifeng;  Feng, Jianghua;  Huang, Heguang;  Feng, JH (reprint author), Xiamen Univ, Fujian Prov Key Lab Plasma & Magnet Resonance, Dept Elect Sci, Xiamen 361005, Peoples R China. jianghua.feng@xmu.edu.cn
Adobe PDF(1113Kb)  |  收藏  |  浏览/下载：830/378  |  提交时间：2015/07/31
Nmr  Metabonomics  Physiological Variation  Laboratory Animals  Genetic Evolution  
Multiple biomarkers of the cytotoxicity induced by BDE-47 in human embryonic kidney cells 期刊论文
CHEMOSPHERE, 2015, 卷号: 126, 页码: 32-39
作者:  Wu, Huifeng;  Cao, Lulu;  Li, Fei;  Lian, Peiwen;  Zhao, Jianmin;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn
Adobe PDF(765Kb)  |  收藏  |  浏览/下载：902/381  |  提交时间：2015/07/31
Bde-47  Hek293 Cells  Cytotoxicity  Cell Apoptosis  Ros  Metabolomics  
Combined metabolome and proteome analysis of the mantle tissue from Pacific oyster Crassostrea gigas exposed to elevated pCO(2) 期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS, 2015, 卷号: 13, 页码: 16-23
作者:  Wei, Lei;  Wang, Qing;  Ning, Xuanxuan;  Mu, Changkao;  Wang, Chunlin;  Cao, Ruiwen;  Wu, Huifeng;  Cong, Ming;  Li, Fei;  Ji, Chenglong;  Zhao, Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
Adobe PDF(588Kb)  |  收藏  |  浏览/下载：993/427  |  提交时间：2015/07/31
Ocean Acidification  Proteomics  Metabolomics  Crassostrea Gigas  
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
Adobe PDF(2093Kb)  |  收藏  |  浏览/下载：827/293  |  提交时间：2015/07/31
Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)