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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载:768/298  |  提交时间:2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(6774Kb)  |  收藏  |  浏览/下载:426/54  |  提交时间:2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
四溴双酚 A 的污染现状及其 生殖内分泌干扰效应的研究进展 期刊论文
海岸科学, 2020, 卷号: 7, 期号: 2, 页码: 10-16
作者:  王 爽;  吉成龙;  吴惠丰
Adobe PDF(447Kb)  |  收藏  |  浏览/下载:427/92  |  提交时间:2021/11/18
四溴双酚 A  污染现状  生殖内分泌干扰效应  
Evaluation on the biomagnification or biodilution of trace metals in global marine food webs by meta-analysis 期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 264, 页码: 11
作者:  Sun, Tao;  Wu, Huifeng;  Wang, Xiaoqing;  Ji, Chenglong;  Shan, Xiujuan;  Li, Fei
浏览  |  Adobe PDF(2296Kb)  |  收藏  |  浏览/下载:721/302  |  提交时间:2021/06/21
Trace metals  Marine food webs  Metal concentration  Trophic transfer  Marine environment  
Global responses to tris(1-chloro-2-propyl)phosphate (TCPP) in rockfish Sebastes schlegeli using integrated proteomic and metabolomic approach 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 724, 页码: 9
作者:  Ji, Chenglong;  Lu, Zhen;  Xu, Lanlan;  Li, Fei;  Cong, Ming;  Shan, Xiujuan;  Wu, Huifeng
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ORGANOPHOSPHATE FLAME RETARDANTS  MESSENGER-RNA EXPRESSION  CELL-ADHESION MOLECULE  EARLY-LIFE STAGES  DEVELOPMENTAL NEUROTOXICITY  SPATIAL-DISTRIBUTION  SYNAPSIN I  PLASTICIZERS  TARGET  PHOSPHATE  
Toxicological effects of As (V) in juvenile rockfish Sebastes schlegelii by a combined metabolomic and proteomic approach 期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: 255, 期号: 2, 页码: 113333
作者:  Xu, LL;  Lu, Z;  Ji, CL;  Cong, M;  Li, F;  Shan, XJ;  Wu, HF
浏览  |  Adobe PDF(1885Kb)  |  收藏  |  浏览/下载:582/298  |  提交时间:2020/07/08
Arsenic  Toxicological effect  Juvenile rockfish  Proteomics  Metabolomics  
Combinatorial immune and stress response, cytoskeleton and signal transduction effects of graphene and triphenyl phosphate (TPP) in mussel Mytilus galloprovincialis 期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2019, 卷号: 378, 页码: UNSP 120778
作者:  Meng, XJ;  Li, F;  Wang, XQ;  Liu, JL;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(1686Kb)  |  收藏  |  浏览/下载:662/331  |  提交时间:2020/07/08
Joint effects  Graphene  Triphenyl phosphate (TPP)  Toxicity  Mussel  
Evaluation of mitochondrial toxicity of cadmium in clam Ruditapes philippinarum using iTRAQ-based proteomics 期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: 251, 页码: 802-810
作者:  Ji, CL;  Lu, Z;  Xu, LL;  Li, F;  Cong, M;  Shan, XJ;  Wu, HF
浏览  |  Adobe PDF(1493Kb)  |  收藏  |  浏览/下载:543/299  |  提交时间:2020/07/08
Cadmium  iTRAQ  Proteomics  Mitochondrial toxicity  Ruditapes philippinarum  
The critical factors affecting typical organophosphate flame retardants to mimetic biomembrane: An integrated in vitro and in silico study 期刊论文
CHEMOSPHERE, 2019, 卷号: 226, 页码: 159-165
作者:  Wang, XQ;  Meng, XJ;  Li, F;  Ding, JW;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(969Kb)  |  收藏  |  浏览/下载:535/217  |  提交时间:2020/07/08
Organophosphate flame retardants (OPFRs)  Quantitative structure-activity relationship (QSAR)  Mimetic biomembrane  Electrochemical impedance spectroscopy (EIS)  Partial least squares (PLS)  
溴系阻燃剂毒理效应的计算模拟预测与环境风险评估进展 期刊论文
生态毒理学报, 2019, 卷号: 14, 期号: 4, 页码: 2-13
作者:  李斐;  王晓晴;  刘佳琳;  孟祥敬;  吉成龙;  吴惠丰
浏览  |  Adobe PDF(784Kb)  |  收藏  |  浏览/下载:769/350  |  提交时间:2020/07/08
溴系阻燃剂  毒理效应  计算毒理学  风险评估  Brominated Flame Retardants (Bfrs)  Toxicological Effect  Computational Toxicology  Risk Assessment