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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：808/310  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Digital gene expression analysis in the gills of Ruditapes philippinarum after nitrite exposure 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 184, 页码: 7
作者:  Lv, Jiasen;  Cao, Tengfei;  Ji, Chenglong;  Cong, Ming;  Zhao, Jianmin;  Wu, Huifeng
浏览  |  Adobe PDF(594Kb)  |  收藏  |  浏览/下载：520/204  |  提交时间：2021/06/22
Digital gene expression  Gills  Ruditapes philippinarum  Nitrite  
Evaluation of mitochondrial toxicity of cadmium in clam Ruditapes philippinarum using iTRAQ-based proteomics 期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: 251, 页码: 802-810
作者:  Ji, CL;  Lu, Z;  Xu, LL;  Li, F;  Cong, M;  Shan, XJ;  Wu, HF
浏览  |  Adobe PDF(1493Kb)  |  收藏  |  浏览/下载：584/324  |  提交时间：2020/07/08
Cadmium  iTRAQ  Proteomics  Mitochondrial toxicity  Ruditapes philippinarum  
Proteomic responses induced by metal pollutions in oysters Crassostrea sikamea 期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2019, 卷号: 37, 期号: 2, 页码: 685-693
作者:  Lu, Z;  Shan, XJ;  Ji, CL;  Zhao, JM;  Wu, HF
浏览  |  Adobe PDF(508Kb)  |  收藏  |  浏览/下载：513/243  |  提交时间：2020/07/08
metal pollution  Crassostrea sikamea  biological effect  proteomics  
The role of GST omega in metabolism and detoxification of arsenic in clam Ruditapes philippinarum 期刊论文
AQUATIC TOXICOLOGY, 2018, 卷号: 204, 页码: 9-18
作者:  Chen, Lizhu;  Wu, Huifeng;  Zhao, Jianmin;  Zhang, Wei;  Zhang, Li;  Sun, Shan;  Yang, Dinglong;  Cheng, Bo;  Wang, Qing
浏览  |  Adobe PDF(1921Kb)  |  收藏  |  浏览/下载：518/301  |  提交时间：2020/07/08
Arsenic  Bioaccumulation  Metabolism  Subcellular distribution  Glutathione S-transferase omega  
A comparative proteomic study on the effects of metal pollution in oysters Crassostrea hongkongensis 期刊论文
MARINE POLLUTION BULLETIN, 2016, 卷号: 112, 期号: 1-2, 页码: 436-442
作者:  Xu, LL;  Ji, CL;  Wu, HF;  Tan, QG;  Wang, WX;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Peoples R China. Email:hfwu@yic.ac.cn
浏览  |  Adobe PDF(1068Kb)  |  收藏  |  浏览/下载：789/340  |  提交时间：2016/12/18
Metal Pollution  Crassostrea Hongkongensis  Hepatopancreas  Proteomics  
Glutathione S-transferase (GST) gene expression profiles in two marine bivalves exposed to BDE-47 and their potential molecular mechanisms 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2015, 卷号: 33, 期号: 3, 页码: 705-713
作者:  Li Fei;  Wu Huifeng;  Wang Qing;  Li Xuehua;  Zhao Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(580Kb)  |  收藏  |  浏览/下载：920/310  |  提交时间：2015/07/31
Glutathione S-transferase (Gst)  Venerupis Philippinarum  Mytilus Galloprovincialis  Molecular Docking  2  Biomarker  2 '  4  4 '-tetrabromodiphenyl Ether (Bde-47)  
Influences of anthropogenic cultivation on C, N and P stoichiometry of reed-dominated coastal wetlands in the Yellow River Delta 期刊论文
GEODERMA, 2014, 卷号: 235, 页码: 227-232
作者:  Qu, Fanzhu;  Yu, Junbao;  Du, Siyao;  Li, Yunzhao;  Lv, Xiaofei;  Ning, Kai;  Wu, Huifeng;  Meng, Ling;  Yu, JB (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Environm Proc, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Peoples R China. junbao.yu@gmail.com
浏览  |  Adobe PDF(629Kb)  |  收藏  |  浏览/下载：903/422  |  提交时间：2015/07/31
Anthropogenic Cultivation  c  Coastal Wetland  n And p Stoichiometry  The Yellow River Delta  
iTRAQ-based quantitative proteomic analyses on the gender-specific responses in mussel Mytilus galloprovincialis to tetrabromobisphenol A 期刊论文
AQUATIC TOXICOLOGY, 2014, 卷号: 157, 页码: 30-40
作者:  Ji, Chenglong;  Wu, Huifeng;  Wei, Lei;  Zhao, Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(2729Kb)  |  收藏  |  浏览/下载：865/356  |  提交时间：2015/07/31
Tetrabromobisphenol a  Toxicological Effects  Mytilus Galloprovincialis  Itraq  Proteomics  
The interaction between organic phosphate ester and p53: An integrated experimental and in silico approach 期刊论文
MARINE POLLUTION BULLETIN, 2014, 卷号: 85, 期号: 2, 页码: 516-521
作者:  Li, Fei;  Li, Renmin;  Yang, Xianhai;  You, Liping;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, YICCAS, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
浏览  |  Adobe PDF(915Kb)  |  收藏  |  浏览/下载：667/246  |  提交时间：2015/07/31
Organophosphate Flame Retardants (Opfrs) P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Multiple Linear Regression (Mlr)