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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：809/311  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：450/54  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
磷酸三苯酯(TPP)和磷酸三(2-氯异丙基)酯(TCPP)诱导人胚肾细胞HEK293凋亡的机制研究 期刊论文
生态毒理学报, 2019, 卷号: 14, 期号: 5, 页码: 123-132
作者:  王晓晴;  刘佳琳;  李斐;  曹天贵;  吴惠丰;  孟祥敬;  吉成龙
浏览  |  Adobe PDF(7902Kb)  |  收藏  |  浏览/下载：700/305  |  提交时间：2020/07/08
有机磷酸酯阻燃剂  磷酸三(2-氯异丙基)酯(Tcpp)  磷酸三苯酯(Tpp)  肾细胞  细胞凋亡  Organophosphate Flame Retardant  Tris (2-chloroisopropyl) Phosphate (Tcpp)  Triphenyl Phosphate(Tpp)  Kidney Cell  Apoptosis  
Digital gene expression analysis in the gills of Ruditapes philippinarum exposed to short- and long-term exposures of ammonia nitrogen 期刊论文
AQUATIC TOXICOLOGY, 2018, 卷号: 194, 页码: 121-131
作者:  Cong, Ming;  Wu, Huifeng;  Cao, Tengfei;  Lv, Jiasen;  Wang, Qing;  Ji, Chenglong;  Li, Chenghua;  Zhao, Jianmin
浏览  |  Adobe PDF(938Kb)  |  收藏  |  浏览/下载：974/579  |  提交时间：2020/07/08
Ruditapes philippinarum  Digital gene expression  Transcriptome  Ammonia nitrogen  Toxicity  
典型持久性有机污染物与抑癌基因相互作用的分子模拟与验证 期刊论文
科学通报, 2015, 卷号: 60, 期号: 19, 页码: 1804-1809
作者:  吴惠丰;  曹璐璐;  李斐;  李雪花;  赵建民
浏览  |  Adobe PDF(1577Kb)  |  收藏  |  浏览/下载：739/322  |  提交时间：2016/12/15
持久性有机污染物  P53  2  分子模拟  2'  光谱法  4  4'-四溴联苯醚(Bde-47)  
Determination and Prediction of the Binding Interaction between Organophosphate Flame Retardants and p53 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2014, 卷号: 27, 期号: 11, 页码: 1918-1925
作者:  Li, Fei;  Yang, Xianhai;  Li, Xuehua;  Li, Renmin;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
浏览  |  Adobe PDF(1104Kb)  |  收藏  |  浏览/下载：908/407  |  提交时间：2015/07/31
Polybrominated Diphenyl Ethers  Thyroid-hormone Receptors  Structural Requirements  Surface Waters  In-silico  Plasticizers  Complex  Air  Regression  Zebrafish  
An Integrated Proteomic and Metabolomic Study on the Chronic Effects of Mercury in Suaeda salsa under an Environmentally Relevant Salinity 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 5, 页码: e64041
作者:  Liu, Xiaoli;  Wu, Huifeng;  Ji, Chenglong;  Wei, Lei;  Zhao, Jianmin;  Yu, Junbao
浏览  |  Adobe PDF(3149Kb)  |  收藏  |  浏览/下载：1005/267  |  提交时间：2013/08/15
Laser-desorption/ionization-time  Protein Disulfide-isomerase  Oxidative Stress  Aspartate-aminotransferase  Saccharomyces-cerevisiae  Gene-expression  Arabidopsis  Tolerance  Responses  Identification