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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：796/307  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：443/54  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
Profiling of microRNAs and mRNAs in marine mussel Mytilus galloprovincialis 期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2020, 卷号: 230, 页码: 108697
作者:  Yu, Deliang;  Wu, Huifeng;  Peng, Xiao;  Ji, Chenglong;  Zhang, Xiaoying;  Song, Jun;  Qu, Junle
Adobe PDF(1152Kb)  |  收藏  |  浏览/下载：749/312  |  提交时间：2020/07/08
CUCUMBER APOSTICHOPUS-JAPONICUS  OYSTER OSTREA-EDULIS  METABOLOMIC ANALYSIS  OXIDATIVE STRESS  DIGESTIVE GLAND  LET-7  EXPRESSION  MIRNAS  IDENTIFICATION  DROSOPHILA  
Proteomic and metabolomic responses in D-shape larval mussels Mytilus galloprovincialis exposed to cadmium and arsenic 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2016, 卷号: 58, 页码: 514-520
作者:  Wu, Huifeng;  Xu, Lanlan;  Ji, Chenglong;  Yu, Deliang;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, YICCAS, Key Lab Coastal Zone Environm Proc,Yantai Inst Co, Yantai 264003, Peoples R China. Email:hfwu@yic.ac.cn
Adobe PDF(921Kb)  |  收藏  |  浏览/下载：722/318  |  提交时间：2016/12/19
Mytilus Galloprovincialis  Cadmium  Arsenic  Biological Effects  Proteomics  Metabolomics  
H-1 NMR-based metabolomics study on the physiological variations during the rat pregnancy process 期刊论文
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2016, 卷号: 423, 期号: C, 页码: 40-50
作者:  Shen, GP;  Li, ZS;  Zhang, Y;  Wu, HF;  Feng, JH;  Feng, JH (reprint author), Xiamen Univ, Dept Elect Sci, Fujian Prov Key Lab Plasma & Magnet Resonance, Xiamen 361005, Peoples R China. jianghua.feng@xmu.edu.cn
Adobe PDF(2812Kb)  |  收藏  |  浏览/下载：4025/487  |  提交时间：2016/05/24
Gestation Period  Nmr  Metabolomics  Pattern Recognition  Physiological Variation  
典型持久性有机污染物与抑癌基因相互作用的分子模拟与验证 期刊论文
科学通报, 2015, 卷号: 60, 期号: 19, 页码: 1804-1809
作者:  吴惠丰;  曹璐璐;  李斐;  李雪花;  赵建民
Adobe PDF(1577Kb)  |  收藏  |  浏览/下载：730/320  |  提交时间：2016/12/15
持久性有机污染物  P53  2  分子模拟  2'  光谱法  4  4'-四溴联苯醚(Bde-47)  
Proteomic and metabolomic responses of clam Ruditapes philippinarum to arsenic exposure under different salinities 期刊论文
AQUATIC TOXICOLOGY, 2013, 卷号: 136, 页码: 91-100
作者:  Wu, Huifeng;  Liu, Xiaoli;  Zhang, Xingyan;  Ji, Chenglong;  Zhao, Jianmin;  Yu, Junbao
Adobe PDF(1417Kb)  |  收藏  |  浏览/下载：1190/445  |  提交时间：2014/07/08
Toxicological Effect  Salinity  Arsenic  Ruditapes Philippinarum  Proteomics  Metabolomics  
Towards a System Level Understanding of Non-Model Organisms Sampled from the Environment: A Network Biology Approach 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2011, 卷号: 7, 期号: 8, 页码: e1002126
作者:  Williams, Tim D.;  Turan, Nil;  Diab, Amer M.;  Wu, Huifeng;  Mackenzie, Carolynn;  Bartie, Katie L.;  Hrydziuszko, Olga;  Lyons, Brett P.;  Stentiford, Grant D.;  Herbert, John M.;  Abraham, Joseph K.;  Katsiadaki, Ioanna;  Leaver, Michael J.;  Taggart, John B.;  George, Stephen G.;  Viant, Mark R.;  Chipman, Kevin J.;  Falciani, Francesco
Adobe PDF(1348Kb)  |  收藏  |  浏览/下载：1146/246  |  提交时间：2011/11/11
Flounder Platichthys-flesus  Histopathological Biomarkers  Pleuronectes-platessa  Endocrine Disruption  Gene-expression  Liver Fibrosis  Marine Fish  Receptor  Microarray  Proteasome  
Molecular phylogenies and evolutionary behavior of AhR (aryl hydrocarbon receptor) pathway genes in aquatic animals: Implications for the toxicology mechanism of some persistent organic pollutants (POPs) 期刊论文
CHEMOSPHERE, 2010, 卷号: 78, 期号: 2, 页码: 193-205
作者:  Zhou, Hailong;  Qu, Ying;  Wu, Huifeng;  Liao, Chunyang;  Zheng, Jiping;  Diao, Xiaoping;  Xue, Qinzhao
Adobe PDF(751Kb)  |  收藏  |  浏览/下载：1309/365  |  提交时间：2011/07/14
Ahr Pathway  Non-synonymous Nucleotide Substitutions (d(n))  Synonymous Nucleotide Substitutions (d(s))  Persistent Organic Pollutants (Pops)