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Abnormality of mussel in the early developmental stages induced by graphene and triphenyl phosphate: In silico toxicogenomic data-mining, in vivo, and toxicity pathway-oriented approach 期刊论文
AQUATIC TOXICOLOGY, 2023, 卷号: 263, 页码: 11
作者:  Wang, Xiaoqing;  Li, Fei;  Meng, Xiangjing;  Xia, Chunlei;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：102/0  |  提交时间：2023/11/15
Plastic additives  Graphene-based nanomaterials  Toxicogenomic data mining  Combined hazards  Developmental abnormality  
Characterization of oxidative damage induced by nanoparticles via mechanism-driven machine learning approaches 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 871, 页码: 11
作者:  Wang, Xiaoqing;  Li, Fei;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：36/0  |  提交时间：2024/01/26
Toxic effects  Machine learning  Risk assessment  Mechanism -driven analysis  TiO2-based engineered nanoparticles(nTiO2)  
Potential adverse outcome pathways with hazard identification of organophosphate esters 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 卷号: 851, 页码: 13
作者:  Wang, Xiaoqing;  Li, Fei;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：207/0  |  提交时间：2023/01/11
Organophosphate esters (OPEs)  Network-centric analysis  Risk assessment  Adverse outcome pathway  Quantitative weight of evidence  
Critical features identification for chemical chronic toxicity based on mechanistic forecast models 期刊论文
ENVIRONMENTAL POLLUTION, 2022, 卷号: 307, 页码: 8
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：253/0  |  提交时间：2022/07/26
Computational toxicology  Machine learning  Structural alerts  Risk assessment  Prioritization rank  
Critical target identification and human health risk ranking of metal ions based on mechanism-driven modeling 期刊论文
CHEMOSPHERE, 2022, 卷号: 301, 页码: 9
作者:  Wang, Xiaoqing;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng;  Li, Fei
收藏  |  浏览/下载：255/0  |  提交时间：2022/07/26
Metal ions  p53  QSAR  Genetic toxicity  Human health risk  
Toxicity pathways of lipid metabolic disorders induced by typical replacement flame retardants via data-driven analysis, in silico and in vitro approaches 期刊论文
CHEMOSPHERE, 2022, 卷号: 287, 页码: 9
作者:  Wang, Xiaoqing;  Wang, Li;  Li, Fei;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：236/0  |  提交时间：2022/06/16
Toxicity pathways  Lipid metabolism disorder  Bibliometric analysis  Computational toxicology  Data-driven analysis  
Graphene-triphenyl phosphate (TPP) co-exposure in the marine environment: Interference with metabolism and immune regulation in mussel Mytilus galloprovincialis 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 卷号: 227, 页码: 8
作者:  Li, Fei;  Meng, Xiangjing;  Wang, Xiaoqing;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：228/0  |  提交时间：2022/06/16
Nanomaterials  Graphene  Organophosphorus ester (OPEs)  Mytilus  Joint effects  Multi-omics  
Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：717/292  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：389/53  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
Evaluation on the biomagnification or biodilution of trace metals in global marine food webs by meta-analysis 期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 264, 页码: 11
作者:  Sun, Tao;  Wu, Huifeng;  Wang, Xiaoqing;  Ji, Chenglong;  Shan, Xiujuan;  Li, Fei
浏览  |  Adobe PDF(2296Kb)  |  收藏  |  浏览/下载：674/291  |  提交时间：2021/06/21
Trace metals  Marine food webs  Metal concentration  Trophic transfer  Marine environment