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Abnormality of mussel in the early developmental stages induced by graphene and triphenyl phosphate: In silico toxicogenomic data-mining, in vivo, and toxicity pathway-oriented approach 期刊论文
AQUATIC TOXICOLOGY, 2023, 卷号: 263, 页码: 11
作者:  Wang, Xiaoqing;  Li, Fei;  Meng, Xiangjing;  Xia, Chunlei;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：102/0  |  提交时间：2023/11/15
Plastic additives  Graphene-based nanomaterials  Toxicogenomic data mining  Combined hazards  Developmental abnormality  
Characterization of oxidative damage induced by nanoparticles via mechanism-driven machine learning approaches 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 871, 页码: 11
作者:  Wang, Xiaoqing;  Li, Fei;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：36/0  |  提交时间：2024/01/26
Toxic effects  Machine learning  Risk assessment  Mechanism -driven analysis  TiO2-based engineered nanoparticles(nTiO2)  
Effects of an Episodic Storm-Induced Flooding Event on the Biogeochemistry of a Shallow, Highly Turbid, Semi-Enclosed Embayment (Laizhou Bay, Bohai Sea) 期刊论文
SUSTAINABILITY, 2023, 卷号: 15, 期号: 1, 页码: 12
作者:  Meng, Ling;  Xing, Qianguo;  Gao, Xuelu;  Ji, Diansheng;  Qu, Fanzhu;  Wang, Xiaoqing;  Ji, Ling
收藏  |  浏览/下载：96/0  |  提交时间：2023/08/17
episodic flood  freshwater inflows  biogeochemical indicators  chlorophyll a  Laizhou Bay  
Graphene Materials Induce Chronic Aquatic Toxicity Through the Regulation of DNA Damage, Metabolism and Oxidative Stress in Daphnia Magna 期刊论文
SSRN, 2023
作者:  Huang, Yang;  Yao, Hongye;  Li, Xuehua;  Li, Fei;  Wang, Xiaoqing;  Fu, Zhiqiang;  Li, Ningjing;  Chen, Jingwen
收藏  |  浏览/下载：49/0  |  提交时间：2024/01/26
Detoxification  Metabolism  Nanostructured materials  Proteins  Toxicity  Transcription  
Potential adverse outcome pathways with hazard identification of organophosphate esters 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 卷号: 851, 页码: 13
作者:  Wang, Xiaoqing;  Li, Fei;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：207/0  |  提交时间：2023/01/11
Organophosphate esters (OPEs)  Network-centric analysis  Risk assessment  Adverse outcome pathway  Quantitative weight of evidence  
Critical features identification for chemical chronic toxicity based on mechanistic forecast models 期刊论文
ENVIRONMENTAL POLLUTION, 2022, 卷号: 307, 页码: 8
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：253/0  |  提交时间：2022/07/26
Computational toxicology  Machine learning  Structural alerts  Risk assessment  Prioritization rank  
Critical target identification and human health risk ranking of metal ions based on mechanism-driven modeling 期刊论文
CHEMOSPHERE, 2022, 卷号: 301, 页码: 9
作者:  Wang, Xiaoqing;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng;  Li, Fei
收藏  |  浏览/下载：255/0  |  提交时间：2022/07/26
Metal ions  p53  QSAR  Genetic toxicity  Human health risk  
Toxicity pathways of lipid metabolic disorders induced by typical replacement flame retardants via data-driven analysis, in silico and in vitro approaches 期刊论文
CHEMOSPHERE, 2022, 卷号: 287, 页码: 9
作者:  Wang, Xiaoqing;  Wang, Li;  Li, Fei;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：236/0  |  提交时间：2022/06/16
Toxicity pathways  Lipid metabolism disorder  Bibliometric analysis  Computational toxicology  Data-driven analysis  
Graphene-triphenyl phosphate (TPP) co-exposure in the marine environment: Interference with metabolism and immune regulation in mussel Mytilus galloprovincialis 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 卷号: 227, 页码: 8
作者:  Li, Fei;  Meng, Xiangjing;  Wang, Xiaoqing;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载：228/0  |  提交时间：2022/06/16
Nanomaterials  Graphene  Organophosphorus ester (OPEs)  Mytilus  Joint effects  Multi-omics  
Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：717/292  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses