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Multiple biomarkers of the cytotoxicity induced by BDE-47 in human embryonic kidney cells 期刊论文
CHEMOSPHERE, 2015, 卷号: 126, 页码: 32-39
作者:  Wu, Huifeng;  Cao, Lulu;  Li, Fei;  Lian, Peiwen;  Zhao, Jianmin;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn
Adobe PDF(765Kb)  |  收藏  |  浏览/下载:875/376  |  提交时间:2015/07/31
Bde-47  Hek293 Cells  Cytotoxicity  Cell Apoptosis  Ros  Metabolomics  
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
Adobe PDF(2093Kb)  |  收藏  |  浏览/下载:808/289  |  提交时间:2015/07/31
Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)  
Determination and Prediction of the Binding Interaction between Organophosphate Flame Retardants and p53 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2014, 卷号: 27, 期号: 11, 页码: 1918-1925
作者:  Li, Fei;  Yang, Xianhai;  Li, Xuehua;  Li, Renmin;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
Adobe PDF(1104Kb)  |  收藏  |  浏览/下载:843/380  |  提交时间:2015/07/31
Polybrominated Diphenyl Ethers  Thyroid-hormone Receptors  Structural Requirements  Surface Waters  In-silico  Plasticizers  Complex  Air  Regression  Zebrafish  
The interaction between organic phosphate ester and p53: An integrated experimental and in silico approach 期刊论文
MARINE POLLUTION BULLETIN, 2014, 卷号: 85, 期号: 2, 页码: 516-521
作者:  Li, Fei;  Li, Renmin;  Yang, Xianhai;  You, Liping;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, YICCAS, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
Adobe PDF(915Kb)  |  收藏  |  浏览/下载:623/231  |  提交时间:2015/07/31
Organophosphate Flame Retardants (Opfrs) P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Multiple Linear Regression (Mlr)  
Metabolic responses of HeLa cells to silica nanoparticles by NMR-based metabolomic analyses 期刊论文
METABOLOMICS, 2013, 卷号: 9, 期号: 4, 页码: 874-886
作者:  Feng, Jianghua;  Li, Jinquan;  Wu, Huifeng;  Chen, Zhong
浏览  |  Adobe PDF(794Kb)  |  收藏  |  浏览/下载:1106/388  |  提交时间:2014/07/08
Silica Nanoparticles  Metabolomic Analysis  Nmr Spectroscopy  Nanomedicine  Hela Cell  
Docking and QSAR study on the binding interactions between polycyclic aromatic hydrocarbons and estrogen receptor 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2012, 卷号: 80, 页码: 273-279
作者:  Li, Fei;  Wu, Huifeng;  Li, Lianzhen;  Li, Xuehua;  Zhao, Jianmin;  Peijnenburg, Willie J. G. M.
浏览  |  Adobe PDF(450Kb)  |  收藏  |  浏览/下载:1090/426  |  提交时间:2013/03/08
Polycyclic Aromatic Hydrocarbons (Pahs)  Estrogenic Activity  Molecular Docking  Quantitative Structure-activity Relationship (Qsar)  Applicability Domain  
Docking and 3D-QSAR studies on the Ah receptor binding affinities of polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2011, 卷号: 32, 期号: 3, 页码: 478-485
作者:  Li, Fei;  Li, Xuehua;  Liu, Xiaoli;  Zhang, Linbao;  You, Liping;  Zhao, Jianmin;  Wu, Huifeng
Adobe PDF(398Kb)  |  收藏  |  浏览/下载:1975/592  |  提交时间:2012/03/06
Qsar  Docking  Partial Least Squares  Polychlorinated Biphenyls (Pcbs)  Dibenzo-p-dioxins (Pcdds)  Dibenzofurans (Pcdfs)  
Identification of two small heat shock proteins with different response profile to cadmium and pathogen stresses in Venerupis philippinarum 期刊论文
CELL STRESS & CHAPERONES, 2010, 卷号: 15, 期号: 6, 页码: 897-904
作者:  Li, Chenghua;  Wang, Lingling;  Ning, Xuanxuan;  Chen, Aiqin;  Zhang, Linbao;  Qin, Song;  Wu, Huifeng;  Zhao, Jianmin
Adobe PDF(1031Kb)  |  收藏  |  浏览/下载:1090/217  |  提交时间:2011/07/21
Venerupis Philippinarum  Small Heat Shock Protein  Time-course Expression  Vibrio Anguillarum  Cadmium Exposure  
Toxicology mechanism of the persistent organic pollutants (POPs) in fish through AhR pathway 期刊论文
TOXICOLOGY MECHANISMS AND METHODS, 2010, 卷号: 20, 期号: 6, 页码: 279-286
作者:  Zhou, Hailong;  Wu, Huifeng;  Liao, Chunyang;  Diao, Xiaoping;  Zhen, Jiping;  Chen, Linlin;  Xue, Qinzhao
Adobe PDF(871Kb)  |  收藏  |  浏览/下载:1584/515  |  提交时间:2011/07/14
Persistent Organic Pollutants  Ahr Pathway  Toxicology Mechanism  Fish