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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：717/292  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Effects of hypoxia in the gills of the Manila clam Ruditapes philippinarum using NMR-based metabolomics 期刊论文
MARINE POLLUTION BULLETIN, 2017, 卷号: 114, 期号: 1, 页码: 84-89
作者:  Zhang, Ying;  Wu, Huifeng;  Wei, Lei;  Xie, Zeping;  Guan, Bo;  Zhang, Y (reprint author), Binzhou Med Univ, Sch Basic Med Sci, 346,Guanhai Rd, Yantai 264003, Peoples R China. zhangying@bzmc.edu.cn
浏览  |  Adobe PDF(1049Kb)  |  收藏  |  浏览/下载：714/333  |  提交时间：2017/04/06
Metabolic Profile  Hypoxia  Ruditapes Philippinarum  Proton Nuclear Magnetic Resonance  Metabolomics  
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
Adobe PDF(2093Kb)  |  收藏  |  浏览/下载：805/289  |  提交时间：2015/07/31
Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)  
Metabolic responses in gills of Manila clam Ruditapes philippinarum exposed to copper using NMR-based metabolomics 期刊论文
MARINE ENVIRONMENTAL RESEARCH, 2011, 卷号: 72, 期号: 1-2, 页码: 33-39
作者:  Zhang, Linbao;  Liu, Xiaoli;  You, Liping;  Zhou, Di;  Wu, Huifeng;  Li, Lianzhen;  Zhao, Jianmin;  Feng, Jianghua;  Yu, Junbao
Adobe PDF(621Kb)  |  收藏  |  浏览/下载：1387/450  |  提交时间：2012/03/06
Copper  Heavy Metal  Toxicity  Metabolites  Biomarkers  Manila Clam  Bioindicator  Metabolomics  
Toxicology mechanism of the persistent organic pollutants (POPs) in fish through AhR pathway 期刊论文
TOXICOLOGY MECHANISMS AND METHODS, 2010, 卷号: 20, 期号: 6, 页码: 279-286
作者:  Zhou, Hailong;  Wu, Huifeng;  Liao, Chunyang;  Diao, Xiaoping;  Zhen, Jiping;  Chen, Linlin;  Xue, Qinzhao
浏览  |  Adobe PDF(871Kb)  |  收藏  |  浏览/下载：1574/513  |  提交时间：2011/07/14
Persistent Organic Pollutants  Ahr Pathway  Toxicology Mechanism  Fish