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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：798/308  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Proteomic analysis revealed gender-specific responses of mussels (Mytilus galloprovincialis) to trichloropropyl phosphate (TCPP) exposure 期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 267, 页码: 11
作者:  Zhong, Mingyu;  Wu, Huifeng;  Li, Fei;  Shan, Xiujuan;  Ji, Chenglong
浏览  |  Adobe PDF(3290Kb)  |  收藏  |  浏览/下载：594/209  |  提交时间：2021/06/07
Trichloropropyl phosphate (TCPP)  Mytilus galloprovincialis  Gender-specific effects  iTRAQ  Proteomics  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：443/54  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
Occurrence and spatial distribution of organophosphorus flame retardants and plasticizers in the Bohai, Yellow and East China seas 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 741, 页码: 9
作者:  Zhong, Mingyu;  Tang, Jianhui;  Guo, Xinyu;  Guo, Chao;  Li, Fei;  Wu, Huifeng
浏览  |  Adobe PDF(1941Kb)  |  收藏  |  浏览/下载：749/306  |  提交时间：2021/06/16
Organophosphate esters  Concentrations and distributions  Seasonal variation  Chinese marginal sea  
Global responses to tris(1-chloro-2-propyl)phosphate (TCPP) in rockfish Sebastes schlegeli using integrated proteomic and metabolomic approach 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 724, 页码: 9
作者:  Ji, Chenglong;  Lu, Zhen;  Xu, Lanlan;  Li, Fei;  Cong, Ming;  Shan, Xiujuan;  Wu, Huifeng
浏览  |  Adobe PDF(1872Kb)  |  收藏  |  浏览/下载：850/379  |  提交时间：2020/07/08
ORGANOPHOSPHATE FLAME RETARDANTS  MESSENGER-RNA EXPRESSION  CELL-ADHESION MOLECULE  EARLY-LIFE STAGES  DEVELOPMENTAL NEUROTOXICITY  SPATIAL-DISTRIBUTION  SYNAPSIN I  PLASTICIZERS  TARGET  PHOSPHATE  
The critical factors affecting typical organophosphate flame retardants to mimetic biomembrane: An integrated in vitro and in silico study 期刊论文
CHEMOSPHERE, 2019, 卷号: 226, 页码: 159-165
作者:  Wang, XQ;  Meng, XJ;  Li, F;  Ding, JW;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(969Kb)  |  收藏  |  浏览/下载：549/223  |  提交时间：2020/07/08
Organophosphate flame retardants (OPFRs)  Quantitative structure-activity relationship (QSAR)  Mimetic biomembrane  Electrochemical impedance spectroscopy (EIS)  Partial least squares (PLS)  
Interaction between organic phosphate ester and p53: An integrated experimental and in silico approach 期刊论文
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 卷号: 255
作者:  Li, Fei
浏览  |  Adobe PDF(915Kb)  |  收藏  |  浏览/下载：355/147  |  提交时间：2020/07/08
Occurrences and distribution characteristics of organophosphate ester flame retardants and plasticizers in the sediments of the Bohai and Yellow Seas, China 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 615, 期号: 0, 页码: 1305-1311
作者:  Zhong, Mingyu;  Wu, Huifeng;  Mi, Wenying;  Li, Fei;  Ji, Chenglong;  Ebinghaus, Ralf;  Tang, Jianhui;  Xie, Zhiyong;  Tang, Jianhui(Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China)
浏览  |  Adobe PDF(1030Kb)  |  收藏  |  浏览/下载：1376/625  |  提交时间：2018/01/10
Tris (2-choroethyl) Phosphate (Tcep)  Tris (2-ethylhexyl) Phosphate (Tehp)  Total Organic Carbon (Toc)  Inventories  
An integrated proteomic and metabolomic study on the gender-specific responses of mussels Mytilus galloprovincialis to tetrabromobisphenol A (TBBPA) 期刊论文
CHEMOSPHERE, 2016, 卷号: 144, 页码: 527-539
作者:  Ji, CL;  Li, F;  Wang, Q;  Zhao, JM;  Sun, ZD;  Wu, HF;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Environm Proc, Key Lab Coastal Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(2260Kb)  |  收藏  |  浏览/下载：1085/330  |  提交时间：2016/04/24
Gender-specific  Mytilus Galloprovincialis  Proteomics  Metabolomics  Tetrabromobisphenol a  
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(2093Kb)  |  收藏  |  浏览/下载：857/302  |  提交时间：2015/07/31
Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)