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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways
期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:
Wang, Xiaoqing
;
Li, Fei
;
Chen, Jingwen
;
Ji, Chenglong
;
Wu, Huifeng
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  |  
Adobe PDF(3938Kb)
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浏览/下载:809/311
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提交时间:2021/05/22
Adverse outcome pathway (AOP)
Comparative toxicogenomics database (CTD)
Triphenyl phosphate (TPP)
Molecular dynamics (MD)
Transcriptome analyses
Proteomic analysis revealed gender-specific responses of mussels (Mytilus galloprovincialis) to trichloropropyl phosphate (TCPP) exposure
期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 267, 页码: 11
作者:
Zhong, Mingyu
;
Wu, Huifeng
;
Li, Fei
;
Shan, Xiujuan
;
Ji, Chenglong
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  |  
Adobe PDF(3290Kb)
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浏览/下载:602/211
  |  
提交时间:2021/06/07
Trichloropropyl phosphate (TCPP)
Mytilus galloprovincialis
Gender-specific effects
iTRAQ
Proteomics
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP)
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:
Wang, Xiaoqing
;
Li, Fei
;
Liu, Jialin
;
Ji, Chenglong
;
Wu, Huifeng
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  |  
Adobe PDF(6774Kb)
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浏览/下载:450/54
  |  
提交时间:2021/06/21
Triphenyl phosphate (TPP)
Multi-omit approach
Hepatotoxicity
Occurrence and spatial distribution of organophosphorus flame retardants and plasticizers in the Bohai, Yellow and East China seas
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 741, 页码: 9
作者:
Zhong, Mingyu
;
Tang, Jianhui
;
Guo, Xinyu
;
Guo, Chao
;
Li, Fei
;
Wu, Huifeng
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Adobe PDF(1941Kb)
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浏览/下载:763/313
  |  
提交时间:2021/06/16
Organophosphate esters
Concentrations and distributions
Seasonal variation
Chinese marginal sea
Global responses to tris(1-chloro-2-propyl)phosphate (TCPP) in rockfish Sebastes schlegeli using integrated proteomic and metabolomic approach
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 724, 页码: 9
作者:
Ji, Chenglong
;
Lu, Zhen
;
Xu, Lanlan
;
Li, Fei
;
Cong, Ming
;
Shan, Xiujuan
;
Wu, Huifeng
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  |  
Adobe PDF(1872Kb)
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浏览/下载:857/381
  |  
提交时间:2020/07/08
ORGANOPHOSPHATE FLAME RETARDANTS
MESSENGER-RNA EXPRESSION
CELL-ADHESION MOLECULE
EARLY-LIFE STAGES
DEVELOPMENTAL NEUROTOXICITY
SPATIAL-DISTRIBUTION
SYNAPSIN I
PLASTICIZERS
TARGET
PHOSPHATE
The critical factors affecting typical organophosphate flame retardants to mimetic biomembrane: An integrated in vitro and in silico study
期刊论文
CHEMOSPHERE, 2019, 卷号: 226, 页码: 159-165
作者:
Wang, XQ
;
Meng, XJ
;
Li, F
;
Ding, JW
;
Ji, CL
;
Wu, HF
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  |  
Adobe PDF(969Kb)
  |  
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  |  
浏览/下载:556/226
  |  
提交时间:2020/07/08
Organophosphate flame retardants (OPFRs)
Quantitative structure-activity relationship (QSAR)
Mimetic biomembrane
Electrochemical impedance spectroscopy (EIS)
Partial least squares (PLS)
Interaction between organic phosphate ester and p53: An integrated experimental and in silico approach
期刊论文
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 卷号: 255
作者:
Li, Fei
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  |  
Adobe PDF(915Kb)
  |  
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  |  
浏览/下载:364/148
  |  
提交时间:2020/07/08
Occurrences and distribution characteristics of organophosphate ester flame retardants and plasticizers in the sediments of the Bohai and Yellow Seas, China
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 615, 期号: 0, 页码: 1305-1311
作者:
Zhong, Mingyu
;
Wu, Huifeng
;
Mi, Wenying
;
Li, Fei
;
Ji, Chenglong
;
Ebinghaus, Ralf
;
Tang, Jianhui
;
Xie, Zhiyong
;
Tang, Jianhui(Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China)
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  |  
Adobe PDF(1030Kb)
  |  
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  |  
浏览/下载:1393/635
  |  
提交时间:2018/01/10
Tris (2-choroethyl) Phosphate (Tcep)
Tris (2-ethylhexyl) Phosphate (Tehp)
Total Organic Carbon (Toc)
Inventories
An integrated proteomic and metabolomic study on the gender-specific responses of mussels Mytilus galloprovincialis to tetrabromobisphenol A (TBBPA)
期刊论文
CHEMOSPHERE, 2016, 卷号: 144, 页码: 527-539
作者:
Ji, CL
;
Li, F
;
Wang, Q
;
Zhao, JM
;
Sun, ZD
;
Wu, HF
;
Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Environm Proc, Key Lab Coastal Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
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  |  
Adobe PDF(2260Kb)
  |  
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  |  
浏览/下载:1092/331
  |  
提交时间:2016/04/24
Gender-specific
Mytilus Galloprovincialis
Proteomics
Metabolomics
Tetrabromobisphenol a
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study
期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:
Li, Fei
;
Cao, Lulu
;
Li, Xuehua
;
Li, Na
;
Wang, Zijian
;
Wu, Huifeng
;
Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
Adobe PDF(2093Kb)
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收藏
  |  
浏览/下载:863/303
  |  
提交时间:2015/07/31
Organophosphate Flame Retardants (Opfrs)
P53
Docking
Quantitative Structure-activity Relationship (Qsar)
Binding Affinity
Partial Least Squares (Pls)