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Molecular diversity and evolution of defensins in the manila clam Ruditapes philippinarum 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2015, 卷号: 47, 期号: 1, 页码: 302-312
作者:  Wang, Q;  Zhang, LB;  Yang, DL;  Yu, Q;  Li, F;  Cong, M;  Ji, CL;  Wu, HF;  Zhao, JM;  Zhao, JM (reprint author), Chinese Acad Sci, Key Lab Coastal Environm Processes & Ecol Remedia, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China. jmzhao@yic.ac.cn
Adobe PDF(1687Kb)  |  收藏  |  浏览/下载:674/284  |  提交时间:2016/04/24
Defensin  Manila Clam  Diversity  Positive Selection  
Multiple biomarkers of the cytotoxicity induced by BDE-47 in human embryonic kidney cells 期刊论文
CHEMOSPHERE, 2015, 卷号: 126, 页码: 32-39
作者:  Wu, Huifeng;  Cao, Lulu;  Li, Fei;  Lian, Peiwen;  Zhao, Jianmin;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn
Adobe PDF(765Kb)  |  收藏  |  浏览/下载:929/391  |  提交时间:2015/07/31
Bde-47  Hek293 Cells  Cytotoxicity  Cell Apoptosis  Ros  Metabolomics  
Toxicological evaluation of two pedigrees of clam Ruditapes philippinarum as bioindicators of heavy metal contaminants using metabolomics 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2015, 卷号: 39, 期号: 2, 页码: 545-554
作者:  Ji, Chenglong;  Cao, Lulu;  Li, Fei;  Li, F (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. fli@yic.ac.cn
Adobe PDF(1591Kb)  |  收藏  |  浏览/下载:712/308  |  提交时间:2015/07/31
Ruditapes Philippinarum  Bioindicators  Ecotoxicology  Heavy Metals  Metabolomics  Nmr  
Combined metabolome and proteome analysis of the mantle tissue from Pacific oyster Crassostrea gigas exposed to elevated pCO(2) 期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS, 2015, 卷号: 13, 页码: 16-23
作者:  Wei, Lei;  Wang, Qing;  Ning, Xuanxuan;  Mu, Changkao;  Wang, Chunlin;  Cao, Ruiwen;  Wu, Huifeng;  Cong, Ming;  Li, Fei;  Ji, Chenglong;  Zhao, Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
Adobe PDF(588Kb)  |  收藏  |  浏览/下载:1020/436  |  提交时间:2015/07/31
Ocean Acidification  Proteomics  Metabolomics  Crassostrea Gigas  
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(2093Kb)  |  收藏  |  浏览/下载:851/301  |  提交时间:2015/07/31
Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)