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A strategy to boost xanthine oxidase and angiotensin converting enzyme inhibitory activities of peptides via molecular docking and module substitution 期刊论文
FOOD CHEMISTRY, 2024, 卷号: 442, 页码: 9
作者:  Meng, Pengfei;  Wang, Yanxin;  Huang, Yumeng;  Liu, Tong;  Ma, Mingxia;  Han, Jiaojiao;  Su, Xiurong;  Li, Wenjun;  Wang, Yanbo;  Lu, Chenyang
收藏  |  浏览/下载:84/0  |  提交时间:2024/05/07
Peptide  Activity boosting strategy  Molecular docking  Module substitution  Xanthine oxidase inhibitory  Angiotensin-converting enzyme inhibitory  
Purification and characterization of a novel angiotensin I-converting enzyme-inhibitory peptide derived from Alaska pollack skins 期刊论文
JOURNAL OF FOOD SCIENCE, 2021, 页码: 11
作者:  Yang, Guilan;  Qin, Song;  Li, Wenjun
Adobe PDF(1714Kb)  |  收藏  |  浏览/下载:473/42  |  提交时间:2021/06/22
Alaska pollack skins protein hydrolysate  angiotensin I-converting enzyme (ACE)-inhibitory peptide  gel filtration chromatography  molecular docking  ultrafiltration  
Graphene quantum dots in alveolar macrophage: uptake-exocytosis, accumulation in nuclei, nuclear responses and DNA cleavage 期刊论文
PARTICLE AND FIBRE TOXICOLOGY, 2018, 卷号: 15, 页码: 45
作者:  Xu, Lina;  Dai, Yanhui;  Wang, Zhenyu;  Zhao, Jian;  Li, Fei;  White, Jason C.;  Xing, Baoshan
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Aminated graphene quantum dots  Macrophages  Endocytosis  Nuclear accumulation  DNA cleavage  Molecular docking  
Glutathione S-transferase (GST) gene expression profiles in two marine bivalves exposed to BDE-47 and their potential molecular mechanisms 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2015, 卷号: 33, 期号: 3, 页码: 705-713
作者:  Li Fei;  Wu Huifeng;  Wang Qing;  Li Xuehua;  Zhao Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
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Glutathione S-transferase (Gst)  Venerupis Philippinarum  Mytilus Galloprovincialis  Molecular Docking  2  Biomarker  2 '  4  4 '-tetrabromodiphenyl Ether (Bde-47)  
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(2093Kb)  |  收藏  |  浏览/下载:863/303  |  提交时间:2015/07/31
Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)  
The interaction between organic phosphate ester and p53: An integrated experimental and in silico approach 期刊论文
MARINE POLLUTION BULLETIN, 2014, 卷号: 85, 期号: 2, 页码: 516-521
作者:  Li, Fei;  Li, Renmin;  Yang, Xianhai;  You, Liping;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, YICCAS, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
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Organophosphate Flame Retardants (Opfrs) P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Multiple Linear Regression (Mlr)  
Docking and QSAR study on the binding interactions between polycyclic aromatic hydrocarbons and estrogen receptor 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2012, 卷号: 80, 页码: 273-279
作者:  Li, Fei;  Wu, Huifeng;  Li, Lianzhen;  Li, Xuehua;  Zhao, Jianmin;  Peijnenburg, Willie J. G. M.
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Polycyclic Aromatic Hydrocarbons (Pahs)  Estrogenic Activity  Molecular Docking  Quantitative Structure-activity Relationship (Qsar)  Applicability Domain  
Docking and 3D-QSAR studies on the Ah receptor binding affinities of polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2011, 卷号: 32, 期号: 3, 页码: 478-485
作者:  Li, Fei;  Li, Xuehua;  Liu, Xiaoli;  Zhang, Linbao;  You, Liping;  Zhao, Jianmin;  Wu, Huifeng
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Qsar  Docking  Partial Least Squares  Polychlorinated Biphenyls (Pcbs)  Dibenzo-p-dioxins (Pcdds)  Dibenzofurans (Pcdfs)  
Noncovalent interactions between hydroxylated polycyclic aromatic hydrocarbon and DNA: Molecular docking and QSAR study 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2011, 卷号: 32, 期号: 3, 页码: 373-381
作者:  Li, Fei;  Li, Xuehua;  Liu, Xiaoli;  Zhang, Linbao;  You, Liping;  Zhao, Jianmin;  Wu, Huifeng
浏览  |  Adobe PDF(501Kb)  |  收藏  |  浏览/下载:1580/501  |  提交时间:2012/03/06
Hydroxylated Polycyclic Aromatic Hydrocarbon (Ho-pah)  Dna  Quantitative Structure-activity Relationship (Qsar)  Binding Interaction  Docking