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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：767/298  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：423/54  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
Toxicological effects of graphene on mussel Mytilus galloprovincialis hemocytes after individual and combined exposure with triphenyl phosphate 期刊论文
MARINE POLLUTION BULLETIN, 2020, 卷号: 151, 页码: 110838
作者:  Meng, Xiangjing;  Li, Fei;  Wang, Xiaoqing;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(2503Kb)  |  收藏  |  浏览/下载：740/305  |  提交时间：2020/07/08
ORGANOPHOSPHATE FLAME RETARDANTS  IN-VITRO  PRISTINE GRAPHENE  OXIDATIVE STRESS  MARINE MUSSEL  CAGED MUSSELS  OXIDE  TOXICITY  NANOPARTICLES  NANOMATERIALS  
The critical factors affecting typical organophosphate flame retardants to mimetic biomembrane: An integrated in vitro and in silico study 期刊论文
CHEMOSPHERE, 2019, 卷号: 226, 页码: 159-165
作者:  Wang, XQ;  Meng, XJ;  Li, F;  Ding, JW;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(969Kb)  |  收藏  |  浏览/下载：530/214  |  提交时间：2020/07/08
Organophosphate flame retardants (OPFRs)  Quantitative structure-activity relationship (QSAR)  Mimetic biomembrane  Electrochemical impedance spectroscopy (EIS)  Partial least squares (PLS)  
Glutathione S-transferase (GST) gene expression profiles in two marine bivalves exposed to BDE-47 and their potential molecular mechanisms 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2015, 卷号: 33, 期号: 3, 页码: 705-713
作者:  Li Fei;  Wu Huifeng;  Wang Qing;  Li Xuehua;  Zhao Jianmin;  Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(580Kb)  |  收藏  |  浏览/下载：886/296  |  提交时间：2015/07/31
Glutathione S-transferase (Gst)  Venerupis Philippinarum  Mytilus Galloprovincialis  Molecular Docking  2  Biomarker  2 '  4  4 '-tetrabromodiphenyl Ether (Bde-47)  
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(2093Kb)  |  收藏  |  浏览/下载：835/295  |  提交时间：2015/07/31
Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)  
Determination and Prediction of the Binding Interaction between Organophosphate Flame Retardants and p53 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2014, 卷号: 27, 期号: 11, 页码: 1918-1925
作者:  Li, Fei;  Yang, Xianhai;  Li, Xuehua;  Li, Renmin;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
浏览  |  Adobe PDF(1104Kb)  |  收藏  |  浏览/下载：873/392  |  提交时间：2015/07/31
Polybrominated Diphenyl Ethers  Thyroid-hormone Receptors  Structural Requirements  Surface Waters  In-silico  Plasticizers  Complex  Air  Regression  Zebrafish  
The interaction between organic phosphate ester and p53: An integrated experimental and in silico approach 期刊论文
MARINE POLLUTION BULLETIN, 2014, 卷号: 85, 期号: 2, 页码: 516-521
作者:  Li, Fei;  Li, Renmin;  Yang, Xianhai;  You, Liping;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, YICCAS, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
浏览  |  Adobe PDF(915Kb)  |  收藏  |  浏览/下载：639/238  |  提交时间：2015/07/31
Organophosphate Flame Retardants (Opfrs) P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Multiple Linear Regression (Mlr)  
Docking and QSAR study on the binding interactions between polycyclic aromatic hydrocarbons and estrogen receptor 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2012, 卷号: 80, 页码: 273-279
作者:  Li, Fei;  Wu, Huifeng;  Li, Lianzhen;  Li, Xuehua;  Zhao, Jianmin;  Peijnenburg, Willie J. G. M.
Adobe PDF(450Kb)  |  收藏  |  浏览/下载：1112/431  |  提交时间：2013/03/08
Polycyclic Aromatic Hydrocarbons (Pahs)  Estrogenic Activity  Molecular Docking  Quantitative Structure-activity Relationship (Qsar)  Applicability Domain  
Docking and 3D-QSAR studies on the Ah receptor binding affinities of polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2011, 卷号: 32, 期号: 3, 页码: 478-485
作者:  Li, Fei;  Li, Xuehua;  Liu, Xiaoli;  Zhang, Linbao;  You, Liping;  Zhao, Jianmin;  Wu, Huifeng
Adobe PDF(398Kb)  |  收藏  |  浏览/下载：2004/597  |  提交时间：2012/03/06
Qsar  Docking  Partial Least Squares  Polychlorinated Biphenyls (Pcbs)  Dibenzo-p-dioxins (Pcdds)  Dibenzofurans (Pcdfs)