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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载：787/305  |  提交时间：2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Proteomic analysis revealed gender-specific responses of mussels (Mytilus galloprovincialis) to trichloropropyl phosphate (TCPP) exposure 期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 267, 页码: 11
作者:  Zhong, Mingyu;  Wu, Huifeng;  Li, Fei;  Shan, Xiujuan;  Ji, Chenglong
浏览  |  Adobe PDF(3290Kb)  |  收藏  |  浏览/下载：589/206  |  提交时间：2021/06/07
Trichloropropyl phosphate (TCPP)  Mytilus galloprovincialis  Gender-specific effects  iTRAQ  Proteomics  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(6774Kb)  |  收藏  |  浏览/下载：438/54  |  提交时间：2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
Occurrence and spatial distribution of organophosphorus flame retardants and plasticizers in the Bohai, Yellow and East China seas 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 741, 页码: 9
作者:  Zhong, Mingyu;  Tang, Jianhui;  Guo, Xinyu;  Guo, Chao;  Li, Fei;  Wu, Huifeng
浏览  |  Adobe PDF(1941Kb)  |  收藏  |  浏览/下载：739/300  |  提交时间：2021/06/16
Organophosphate esters  Concentrations and distributions  Seasonal variation  Chinese marginal sea  
Global responses to tris(1-chloro-2-propyl)phosphate (TCPP) in rockfish Sebastes schlegeli using integrated proteomic and metabolomic approach 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 724, 页码: 9
作者:  Ji, Chenglong;  Lu, Zhen;  Xu, Lanlan;  Li, Fei;  Cong, Ming;  Shan, Xiujuan;  Wu, Huifeng
浏览  |  Adobe PDF(1872Kb)  |  收藏  |  浏览/下载：846/378  |  提交时间：2020/07/08
ORGANOPHOSPHATE FLAME RETARDANTS  MESSENGER-RNA EXPRESSION  CELL-ADHESION MOLECULE  EARLY-LIFE STAGES  DEVELOPMENTAL NEUROTOXICITY  SPATIAL-DISTRIBUTION  SYNAPSIN I  PLASTICIZERS  TARGET  PHOSPHATE  
The critical factors affecting typical organophosphate flame retardants to mimetic biomembrane: An integrated in vitro and in silico study 期刊论文
CHEMOSPHERE, 2019, 卷号: 226, 页码: 159-165
作者:  Wang, XQ;  Meng, XJ;  Li, F;  Ding, JW;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(969Kb)  |  收藏  |  浏览/下载：546/223  |  提交时间：2020/07/08
Organophosphate flame retardants (OPFRs)  Quantitative structure-activity relationship (QSAR)  Mimetic biomembrane  Electrochemical impedance spectroscopy (EIS)  Partial least squares (PLS)  
Occurrences and distribution characteristics of organophosphate ester flame retardants and plasticizers in the sediments of the Bohai and Yellow Seas, China 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 615, 期号: 0, 页码: 1305-1311
作者:  Zhong, Mingyu;  Wu, Huifeng;  Mi, Wenying;  Li, Fei;  Ji, Chenglong;  Ebinghaus, Ralf;  Tang, Jianhui;  Xie, Zhiyong;  Tang, Jianhui(Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China)
浏览  |  Adobe PDF(1030Kb)  |  收藏  |  浏览/下载：1370/621  |  提交时间：2018/01/10
Tris (2-choroethyl) Phosphate (Tcep)  Tris (2-ethylhexyl) Phosphate (Tehp)  Total Organic Carbon (Toc)  Inventories  
An integrated proteomic and metabolomic study on the gender-specific responses of mussels Mytilus galloprovincialis to tetrabromobisphenol A (TBBPA) 期刊论文
CHEMOSPHERE, 2016, 卷号: 144, 页码: 527-539
作者:  Ji, CL;  Li, F;  Wang, Q;  Zhao, JM;  Sun, ZD;  Wu, HF;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Environm Proc, Key Lab Coastal Environm Proc, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(2260Kb)  |  收藏  |  浏览/下载：1081/330  |  提交时间：2016/04/24
Gender-specific  Mytilus Galloprovincialis  Proteomics  Metabolomics  Tetrabromobisphenol a  
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(2093Kb)  |  收藏  |  浏览/下载：851/301  |  提交时间：2015/07/31
Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)  
Determination and Prediction of the Binding Interaction between Organophosphate Flame Retardants and p53 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2014, 卷号: 27, 期号: 11, 页码: 1918-1925
作者:  Li, Fei;  Yang, Xianhai;  Li, Xuehua;  Li, Renmin;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
浏览  |  Adobe PDF(1104Kb)  |  收藏  |  浏览/下载：894/401  |  提交时间：2015/07/31
Polybrominated Diphenyl Ethers  Thyroid-hormone Receptors  Structural Requirements  Surface Waters  In-silico  Plasticizers  Complex  Air  Regression  Zebrafish