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Critical features identification for chemical chronic toxicity based on mechanistic forecast models 期刊论文
ENVIRONMENTAL POLLUTION, 2022, 卷号: 307, 页码: 8
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng
收藏  |  浏览/下载:289/0  |  提交时间:2022/07/26
Computational toxicology  Machine learning  Structural alerts  Risk assessment  Prioritization rank  
Effect of microplastics on aquatic biota: A hormetic perspective 期刊论文
ENVIRONMENTAL POLLUTION, 2021, 卷号: 285, 页码: 10
作者:  Sun, Tao;  Zhan, Junfei;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
Adobe PDF(4998Kb)  |  收藏  |  浏览/下载:765/238  |  提交时间:2021/10/21
Plastic pollution  Aquatic environment  Dose response  Risk assessment  Environmentally relevant concentrations  
Dose-dependent responses of metabolism and tissue injuries in clam Ruditapes philippinarum after subchronic exposure to cadmium 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2021, 卷号: 779, 页码: 11
作者:  Zhan, Junfei;  Wang, Shuang;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(2610Kb)  |  收藏  |  浏览/下载:643/312  |  提交时间:2021/10/20
Cadmium  Dose-response  Hormesis  Metabolomics  Ruditapes philippinarum  Tissue injuries  
Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载:808/310  |  提交时间:2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Global characterization of dose-dependent effects of cadmium in clam Ruditapes philippinarum 期刊论文
ENVIRONMENTAL POLLUTION, 2021, 卷号: 273, 页码: 9
作者:  Zhan, Junfei;  Wang, Shuang;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(1425Kb)  |  收藏  |  浏览/下载:651/234  |  提交时间:2021/05/22
Benchmark dose  Cadmium  Dose-dependent effects  Ruditapes philippinarum  Transcriptomics  
Evaluation on the biomagnification or biodilution of trace metals in global marine food webs by meta-analysis 期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 264, 页码: 11
作者:  Sun, Tao;  Wu, Huifeng;  Wang, Xiaoqing;  Ji, Chenglong;  Shan, Xiujuan;  Li, Fei
浏览  |  Adobe PDF(2296Kb)  |  收藏  |  浏览/下载:777/325  |  提交时间:2021/06/21
Trace metals  Marine food webs  Metal concentration  Trophic transfer  Marine environment  
The critical factors affecting typical organophosphate flame retardants to mimetic biomembrane: An integrated in vitro and in silico study 期刊论文
CHEMOSPHERE, 2019, 卷号: 226, 页码: 159-165
作者:  Wang, XQ;  Meng, XJ;  Li, F;  Ding, JW;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(969Kb)  |  收藏  |  浏览/下载:555/225  |  提交时间:2020/07/08
Organophosphate flame retardants (OPFRs)  Quantitative structure-activity relationship (QSAR)  Mimetic biomembrane  Electrochemical impedance spectroscopy (EIS)  Partial least squares (PLS)  
Gill damage and neurotoxicity of ammonia nitrogen on the clam Ruditapes philippinarum 期刊论文
ECOTOXICOLOGY, 2017, 卷号: 26, 期号: 3, 页码: 459-469
作者:  Cong, Ming;  Wu, Huifeng;  Yang, Haiping;  Zhao, Jianmin;  Lv, Jiasen;  Wu, HF
浏览  |  Adobe PDF(2124Kb)  |  收藏  |  浏览/下载:951/439  |  提交时间:2017/06/21
Ammonia Nitrogen  Gill Damage  Neurotoxicity  Ruditapes Philippinarum  
Effects of hypoxia in the gills of the Manila clam Ruditapes philippinarum using NMR-based metabolomics 期刊论文
MARINE POLLUTION BULLETIN, 2017, 卷号: 114, 期号: 1, 页码: 84-89
作者:  Zhang, Ying;  Wu, Huifeng;  Wei, Lei;  Xie, Zeping;  Guan, Bo;  Zhang, Y (reprint author), Binzhou Med Univ, Sch Basic Med Sci, 346,Guanhai Rd, Yantai 264003, Peoples R China. zhangying@bzmc.edu.cn
浏览  |  Adobe PDF(1049Kb)  |  收藏  |  浏览/下载:778/356  |  提交时间:2017/04/06
Metabolic Profile  Hypoxia  Ruditapes Philippinarum  Proton Nuclear Magnetic Resonance  Metabolomics  
Metabolic responses to metal pollution in shrimp Crangon affinis from the sites along the Laizhou Bay in the Bohai Sea 期刊论文
MARINE POLLUTION BULLETIN, 2016, 卷号: 113, 期号: 1-2, 页码: 536-541
作者:  Xu, Lanlan;  Ji, Chenglong;  Zhao, Jianmin;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc, YICCAS,Shandong Prov Key Lab Coastal Zone Environ, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
浏览  |  Adobe PDF(964Kb)  |  收藏  |  浏览/下载:983/357  |  提交时间:2017/03/02
Laizhou Bay  Metal Pollution  Crangon Affinis  Metabolomics  H-1 Nmr