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Critical target identification and human health risk ranking of metal ions based on mechanism-driven modeling 期刊论文
CHEMOSPHERE, 2022, 卷号: 301, 页码: 9
作者:  Wang, Xiaoqing;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng;  Li, Fei
收藏  |  浏览/下载:295/0  |  提交时间:2022/07/26
Metal ions  p53  QSAR  Genetic toxicity  Human health risk  
Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways 期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:  Wang, Xiaoqing;  Li, Fei;  Chen, Jingwen;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(3938Kb)  |  收藏  |  浏览/下载:775/300  |  提交时间:2021/05/22
Adverse outcome pathway (AOP)  Comparative toxicogenomics database (CTD)  Triphenyl phosphate (TPP)  Molecular dynamics (MD)  Transcriptome analyses  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(6774Kb)  |  收藏  |  浏览/下载:432/54  |  提交时间:2021/06/21
Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
Toxicological effects of graphene on mussel Mytilus galloprovincialis hemocytes after individual and combined exposure with triphenyl phosphate 期刊论文
MARINE POLLUTION BULLETIN, 2020, 卷号: 151, 页码: 110838
作者:  Meng, Xiangjing;  Li, Fei;  Wang, Xiaoqing;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
浏览  |  Adobe PDF(2503Kb)  |  收藏  |  浏览/下载:754/309  |  提交时间:2020/07/08
ORGANOPHOSPHATE FLAME RETARDANTS  IN-VITRO  PRISTINE GRAPHENE  OXIDATIVE STRESS  MARINE MUSSEL  CAGED MUSSELS  OXIDE  TOXICITY  NANOPARTICLES  NANOMATERIALS  
The critical factors affecting typical organophosphate flame retardants to mimetic biomembrane: An integrated in vitro and in silico study 期刊论文
CHEMOSPHERE, 2019, 卷号: 226, 页码: 159-165
作者:  Wang, XQ;  Meng, XJ;  Li, F;  Ding, JW;  Ji, CL;  Wu, HF
浏览  |  Adobe PDF(969Kb)  |  收藏  |  浏览/下载:537/218  |  提交时间:2020/07/08
Organophosphate flame retardants (OPFRs)  Quantitative structure-activity relationship (QSAR)  Mimetic biomembrane  Electrochemical impedance spectroscopy (EIS)  Partial least squares (PLS)  
Bioaccumulation of decabromodiphenyl ether affects the antioxidant system in the clam Mactra veneriformis 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2019, 卷号: 68, 页码: 19-26
作者:  Zhu, N;  Yang, YY;  Xu, H;  Wang, Q;  Wei, YY;  Li, MZ;  Li, F;  Wang, YQ;  Zhang, HW;  Liu, YH;  Wang, XM;  Fang, Y
浏览  |  Adobe PDF(926Kb)  |  收藏  |  浏览/下载:552/257  |  提交时间:2020/07/08
Decabromodiphenyl ether  Antioxidant enzymes  Bioaccumulation  Mactra venerifonnis  
Graphene quantum dots in alveolar macrophage: uptake-exocytosis, accumulation in nuclei, nuclear responses and DNA cleavage 期刊论文
PARTICLE AND FIBRE TOXICOLOGY, 2018, 卷号: 15, 页码: 45
作者:  Xu, Lina;  Dai, Yanhui;  Wang, Zhenyu;  Zhao, Jian;  Li, Fei;  White, Jason C.;  Xing, Baoshan
浏览  |  Adobe PDF(7464Kb)  |  收藏  |  浏览/下载:500/133  |  提交时间:2020/07/08
Aminated graphene quantum dots  Macrophages  Endocytosis  Nuclear accumulation  DNA cleavage  Molecular docking  
Interaction between organic phosphate ester and p53: An integrated experimental and in silico approach 期刊论文
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 卷号: 255
作者:  Li, Fei
浏览  |  Adobe PDF(915Kb)  |  收藏  |  浏览/下载:328/144  |  提交时间:2020/07/08
Rational Selection of the 3D Structure of Biomacromolecules for Molecular Docking Studies on the Mechanism of Endocrine Disruptor Action 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 卷号: 29, 期号: 9, 页码: 1565-1570
作者:  Yang, Xianhai;  Liu, Huihui;  Liu, Jining;  Li, Fei;  Li, Xuehua;  Shi, Lili;  Chen, Jingwen;  Liu, JB (reprint author) Minist Environm Protect, Nanjing Inst Environm Sci, 8 Jiangwangmiao Steet, Nanjing 210042, Jiangsu, Peoples R China.;  Chen, JW (reprint author)Show the Organization-Enhanced name(s) Dalian Univ Technol, Sch Environm Sci & Technol, Linggong Rd 2, Dalian 116024, Peoples R China. ljn@nies.org;  jwchen@dlut.edu.cn
浏览  |  Adobe PDF(2663Kb)  |  收藏  |  浏览/下载:734/308  |  提交时间:2016/11/30
Polybrominated Diphenyl Ethers  Thyroid-hormone-binding  Human Serum-albumin  In-vitro  Estrogen-receptor  Risk-assessment  Recombinant Transthyretin  Scientific Statement  Evolutionary Changes  Chemicals  
DNA Nanostructure-Based Magnetic Beads for Potentiometric Aptasensing 期刊论文
ANALYTICAL CHEMISTRY, 2015, 卷号: 87, 期号: 13, 页码: 6465-6469
作者:  Ding, Jiawang;  Gu, Yue;  Li, Fei;  Zhang, Hongxia;  Qin, Wei
浏览  |  Adobe PDF(1205Kb)  |  收藏  |  浏览/下载:997/305  |  提交时间:2015/08/10
Hybridization Chain-reaction  Bisphenol-a  Label-free  Electrochemical Detection  Membrane Electrodes  Sensors  Aptamer  Complex  Amplification  Protamine