| Dose-dependent effects induced by cadmium in polychaete Perinereis aibuhitensis | |
Liu, Feng; Lu, Zhen; Wu, Huifeng ; Ji, Chenglong
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| 发表期刊 | ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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| ISSN | 0147-6513 |
| 2019-03 | |
| 卷号 | 169页码:714-721 |
| 关键词 | Cadmium Dose-dependent Toxicological effects Hormesis Perinereis aibuhitensis |
| 研究领域 | Environmental Sciences & Ecology ; Toxicology |
| DOI | 10.1016/j.ecoenv.2018.11.098 |
| 产权排序 | [Liu, Feng] China Agr Univ, Yantai Res Inst, Ocean Coll, Yantai 264670, Peoples R China; [Lu, Zhen; Wu, Huifeng; Ji, Chenglong] Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266237, Peoples R China; [Lu, Zhen; Wu, Huifeng; Ji, Chenglong] Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Lu, Zhen; Wu, Huifeng; Ji, Chenglong] YICCAS, Shandong Prov Key Lab Coastal Environm Proc, Yantai 264003, Peoples R China |
| 作者部门 | 海岸带环境过程实验室 |
| 英文摘要 | Cadmium is a known metal contaminant in the Bohai Sea. In this study, the dose-dependent responses induced by Cd were characterized in marine polychaete Perinereis aibuhitensis using the endpoints, including activities of enzymes, expression levels of stress-responsive genes and metabolic responses. Both enzyme activities and gene expression levels exhibited the hormetic effects induced by Cd in P. aibuhitensis, as shown by the typical U-shaped or inverted U-shaped response profiles. The highest concentration (1280 mu g/L) of Cd exposure induced obvious oxidative stresses. NMR-based metabolomics revealed that Cd induced both linear dose-dependent effects (69.13% of the total variation) and a relatively slight hormesis (5.54% of the total variation) in energy metabolism in P. aibuhitensis at metabolite level. In details, Cd exposures linearly reduced the consumption of amino acids and enhanced the consumption of glucose for energy supply, resulting in elevated contents of amino acids and depleted contents of glucose. Additionally, Cd treatments induced hormesis in the conversion of ATP hydrolysis to AMP. This work suggested that the hormetic effects should be considered in the ecological risk assessment for the environmental pollutants. |
| 文章类型 | Article |
| 资助机构 | National Natural Science Foundation of China [41676114] ; National Key Basic Research Program of China [2015CB453303] ; Qingdao National Laboratory for Marine Science and Technology [QNLM201701] ; Youth Innovation Promotion Association CAS [2015169] |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | SHRIMP CRANGON-AFFINIS ; METABOLIC-RESPONSES ; METAL POLLUTION ; HORMESIS ; TOXICITY |
| 研究领域[WOS] | Environmental Sciences ; Toxicology |
| WOS记录号 | WOS:000456226600085 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/24641 |
| 专题 | 中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室 中国科学院海岸带环境过程与生态修复重点实验室 |
| 作者单位 | 1.China Agr Univ, Yantai Res Inst, Ocean Coll, Yantai 264670, Peoples R China; 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266237, Peoples R China; 3.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; 4.YICCAS, Shandong Prov Key Lab Coastal Environm Proc, Yantai 264003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Feng,Lu, Zhen,Wu, Huifeng,et al. Dose-dependent effects induced by cadmium in polychaete Perinereis aibuhitensis[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2019,169:714-721. |
| APA | Liu, Feng,Lu, Zhen,Wu, Huifeng,&Ji, Chenglong.(2019).Dose-dependent effects induced by cadmium in polychaete Perinereis aibuhitensis.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,169,714-721. |
| MLA | Liu, Feng,et al."Dose-dependent effects induced by cadmium in polychaete Perinereis aibuhitensis".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 169(2019):714-721. |
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