Individual and Combined Toxicities of Benzo[a]pyrene and 2,2',4,4'-Tetrabromodiphenyl Ether on Early Life Stages of the Pacific Oyster, Crassostrea gigas

doi:10.1007/s00128-017-2164-9

	Individual and Combined Toxicities of Benzo[a]pyrene and 2,2',4,4'-Tetrabromodiphenyl Ether on Early Life Stages of the Pacific Oyster, Crassostrea gigas
	Xie, Jia 1,2,3; Yang, Dinglong1,2,3 ; Sun, Xiyan 1,2; Cao, Ruiwen 1,2,3; Chen, Lizhu 1,2,3; Wang, Qing1 ; Li, Fei1 ; Wu, Huifeng1 ; Ji, Chenglong1 ; Cong, Ming1 ; Zhao, Jianmin1,2 ; Wang, Qing(Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China); Zhao, Jianmin(Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China)
发表期刊	BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
ISSN	0007-4861
	2017-11-01
卷号	99 期号:5 页码:582-588
关键词	Embryotoxicity Larval Mortality Genotoxicity Bap Bde-47 Combined Toxicity
DOI	10.1007/s00128-017-2164-9
产权排序	第1完成单位; 第2完成单位
英文摘要	Persistent organic pollutants (POPs) are ubiquitous and coexisted in the aquatic environment. Individual and combined toxic effects of benzo[a]pyrene (BaP) and 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on embryogenesis, and larval survival of the Pacific oyster were investigated. The EC50 values of BaP, BDE-47 and their mixture on embryogenesis were 18.4, 203.3 and 72.0 A mu g/L respectively, while the LC50 values for 96 h larval mortality were 26.8, 244.5 and 108.9 A mu g/L respectively. The Marking-Dawson additive toxicity indices were -0.02 and -0.19, indicating an additive effect with a trend to antagonism. In addition, DNA strand breaks were also observed in oyster embryos after exposure. Our study suggests that BaP and BDE-47 exposure can cause developmental abnormalities, DNA damage and larval mortality. Furthermore, the toxicity of the mixture is slightly lower than individual pollutant. These data will be helpful to predict the toxicity of organic pollutants, and provide criteria for marine water quality standards.
文章类型	Article
资助机构	Key Research Program of the Chinese Academy of Sciences(KZZD-EW-14) ; National Natural Science Foundation of China(41576122) ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDA11020702) ; Youth Innovation Promotion Association of CAS(2016196)
收录类别	SCI
语种	英语
关键词[WOS]	SCALLOP CHLAMYS-FARRERI ; RISK-ASSESSMENT ; IMMUNE FUNCTION ; BOHAI SEA ; EXPOSURE ; EMBRYO ; BDE-47 ; CHINA ; BENZO(A)PYRENE ; EMBRYOGENESIS
研究领域[WOS]	Environmental Sciences & Ecology ; Toxicology
WOS记录号	WOS:000415991900008
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/23495
专题	中国科学院海岸带环境过程与生态修复重点实验室海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
通讯作者	Wang, Qing; Zhao, Jianmin; Wang, Qing(Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China); Zhao, Jianmin(Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China)
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Muping Coastal Environm Res Stn, Yantai Inst Coastal Zone Res YIC, Yantai 264003, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Xie, Jia,Yang, Dinglong,Sun, Xiyan,et al. Individual and Combined Toxicities of Benzo[a]pyrene and 2,2',4,4'-Tetrabromodiphenyl Ether on Early Life Stages of the Pacific Oyster, Crassostrea gigas[J]. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY,2017,99(5):582-588.
APA	Xie, Jia.,Yang, Dinglong.,Sun, Xiyan.,Cao, Ruiwen.,Chen, Lizhu.,...&Zhao, Jianmin.(2017).Individual and Combined Toxicities of Benzo[a]pyrene and 2,2',4,4'-Tetrabromodiphenyl Ether on Early Life Stages of the Pacific Oyster, Crassostrea gigas.BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY,99(5),582-588.
MLA	Xie, Jia,et al."Individual and Combined Toxicities of Benzo[a]pyrene and 2,2',4,4'-Tetrabromodiphenyl Ether on Early Life Stages of the Pacific Oyster, Crassostrea gigas".BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 99.5(2017):582-588.