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化学品甲状腺干扰效应的计算毒理学研究进展 期刊论文
科学通报, 2015, 卷号: 60, 期号: 19, 页码: 1761-1771
作者:  杨先海;  陈景文;  李斐
浏览  |  Adobe PDF(1970Kb)  |  收藏  |  浏览/下载：784/336  |  提交时间：2016/12/15
甲状腺干扰效应  甲状腺干扰物  计算毒理学  分子模拟  定量构效关系  
A defensin from clam Venerupis philippinarum: Molecular characterization, localization, antibacterial activity, and mechanism of action 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2015, 卷号: 51, 期号: 1, 页码: 29-38
作者:  Zhang, LB;  Yang, DL;  Wang, Q;  Yuan, ZY;  Wu, HF;  Pei, D;  Cong, M;  Li, F;  Ji, CL;  Zhao, JM;  Wu, HF (reprint author), YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn;  jmzhao@yic.ac.cn
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Venerupis Philippinarum  Defensin  Molecular Characterization  Tissue Distribution  Antimicrobial Activity  Membrane Lesions  
Toxicological evaluation of two pedigrees of clam Ruditapes philippinarum as bioindicators of heavy metal contaminants using metabolomics 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2015, 卷号: 39, 期号: 2, 页码: 545-554
作者:  Ji, Chenglong;  Cao, Lulu;  Li, Fei;  Li, F (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. fli@yic.ac.cn
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Ruditapes Philippinarum  Bioindicators  Ecotoxicology  Heavy Metals  Metabolomics  Nmr  
Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
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Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)