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Critical target identification and human health risk ranking of metal ions based on mechanism-driven modeling 期刊论文
CHEMOSPHERE, 2022, 卷号: 301, 页码: 9
作者:  Wang, Xiaoqing;  Teng, Yuefa;  Ji, Chenglong;  Wu, Huifeng;  Li, Fei
收藏  |  浏览/下载:289/0  |  提交时间:2022/07/26
Metal ions  p53  QSAR  Genetic toxicity  Human health risk  
Evidence-based meta-analysis of the genotoxicity induced by microplastics in aquatic organisms at environmentally relevant concentrations 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2021, 卷号: 783, 页码: 9
作者:  Sun, Tao;  Zhan, Junfei;  Li, Fei;  Ji, Chenglong;  Wu, Huifeng
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Microplastics  Aquatic organisms  Genotoxicity  Meta-analysis  Environmentally relevant concentrations  
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:  Wang, Xiaoqing;  Li, Fei;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
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Triphenyl phosphate (TPP)  Multi-omit approach  Hepatotoxicity  
Toxicological effects of graphene on mussel Mytilus galloprovincialis hemocytes after individual and combined exposure with triphenyl phosphate 期刊论文
MARINE POLLUTION BULLETIN, 2020, 卷号: 151, 页码: 110838
作者:  Meng, Xiangjing;  Li, Fei;  Wang, Xiaoqing;  Liu, Jialin;  Ji, Chenglong;  Wu, Huifeng
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ORGANOPHOSPHATE FLAME RETARDANTS  IN-VITRO  PRISTINE GRAPHENE  OXIDATIVE STRESS  MARINE MUSSEL  CAGED MUSSELS  OXIDE  TOXICITY  NANOPARTICLES  NANOMATERIALS  
Interaction between organic phosphate ester and p53: An integrated experimental and in silico approach 期刊论文
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 卷号: 255
作者:  Li, Fei
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Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study 期刊论文
TOXICOLOGY LETTERS, 2015, 卷号: 232, 期号: 2, 页码: 533-541
作者:  Li, Fei;  Cao, Lulu;  Li, Xuehua;  Li, Na;  Wang, Zijian;  Wu, Huifeng;  Wu, HF (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. hfwu@yic.ac.cn
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Organophosphate Flame Retardants (Opfrs)  P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Partial Least Squares (Pls)  
Determination and Prediction of the Binding Interaction between Organophosphate Flame Retardants and p53 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2014, 卷号: 27, 期号: 11, 页码: 1918-1925
作者:  Li, Fei;  Yang, Xianhai;  Li, Xuehua;  Li, Renmin;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Shandong, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
Adobe PDF(1104Kb)  |  收藏  |  浏览/下载:873/392  |  提交时间:2015/07/31
Polybrominated Diphenyl Ethers  Thyroid-hormone Receptors  Structural Requirements  Surface Waters  In-silico  Plasticizers  Complex  Air  Regression  Zebrafish  
The interaction between organic phosphate ester and p53: An integrated experimental and in silico approach 期刊论文
MARINE POLLUTION BULLETIN, 2014, 卷号: 85, 期号: 2, 页码: 516-521
作者:  Li, Fei;  Li, Renmin;  Yang, Xianhai;  You, Liping;  Zhao, Jianmin;  Wu, Huifeng;  Li, F (reprint author), Chinese Acad Sci, YICCAS, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China. fli@yic.ac.cn;  hfwu@yic.ac.cn
浏览  |  Adobe PDF(915Kb)  |  收藏  |  浏览/下载:642/239  |  提交时间:2015/07/31
Organophosphate Flame Retardants (Opfrs) P53  Docking  Quantitative Structure-activity Relationship (Qsar)  Binding Affinity  Multiple Linear Regression (Mlr)  
Noncovalent interactions between hydroxylated polycyclic aromatic hydrocarbon and DNA: Molecular docking and QSAR study 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2011, 卷号: 32, 期号: 3, 页码: 373-381
作者:  Li, Fei;  Li, Xuehua;  Liu, Xiaoli;  Zhang, Linbao;  You, Liping;  Zhao, Jianmin;  Wu, Huifeng
浏览  |  Adobe PDF(501Kb)  |  收藏  |  浏览/下载:1550/491  |  提交时间:2012/03/06
Hydroxylated Polycyclic Aromatic Hydrocarbon (Ho-pah)  Dna  Quantitative Structure-activity Relationship (Qsar)  Binding Interaction  Docking