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Exposure to microplastics reduces the bioaccumulation of sulfamethoxazole but enhances its effects on gut microbiota and the antibiotic resistome of mice 期刊论文
CHEMOSPHERE, 2022, 卷号: 294, 页码: 7
作者:  Liu, Jin;  Lv, Min;  Sun, Anqi;  Ding, Jing;  Wang, Yunqing;  Chang, Xianbo;  Chen, Lingxin
收藏  |  浏览/下载：335/0  |  提交时间：2022/08/13
Microplastics  Antibiotic  Bioaccumulation  Antibiotic resistance genes  Synergistic effect  
Biotransformation mechanism of Vibrio diabolicus to sulfamethoxazole at transcriptional level 期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2021, 卷号: 411, 页码: 10
作者:  Wang, Qiaoning;  Wang, Hongdan;  Jiang, Yaru;  Lv, Min;  Wang, Xiaoyan;  Chen, Lingxin
浏览  |  Adobe PDF(3481Kb)  |  收藏  |  浏览/下载：478/38  |  提交时间：2021/05/22
Sulfamethoxazole  Vibrio diabolicus strain L2-2  Transcriptome  Biotransformation  Resistance  
A high-selectivity fluorescent probe for hypoxia imaging in cells and a tumor-bearing mouse model 期刊论文
ANALYST, 2020, 卷号: 145, 期号: 4, 页码: 1389-1395
作者:  Wang, Y;  Han, XY;  Zhang, X;  Zhang, L;  Chen, LX
浏览  |  Adobe PDF(3035Kb)  |  收藏  |  浏览/下载：649/321  |  提交时间：2020/07/08
NITROREDUCTASE DETECTION  RESISTANCE  
近海环境中抗生素分析样品前处理技术的研究进展 期刊论文
色谱, 2020, 卷号: 38, 期号: 1, 页码: 95-103
作者:  吕敏;  陈令新
浏览  |  Adobe PDF(3422Kb)  |  收藏  |  浏览/下载：640/276  |  提交时间：2020/07/08
抗生素  近海  前处理技术  综述  antibiotics  coastal  pretreatment techniques  review  The widespread and massive usage of antibiotics for the prevention and treatment of diseases in human and animals have resulted in their continuous discharge into the environment, and finally, into the coastal environment through various pathways. Accumulation of antibiotics in aquatic organisms poses a great threat to ecological and human health, especially because it facilitates the generation and spread of bacterial resistance. Given the diverse range of antibiotics with various features, as well as their presence at low concentrations in the environment, it is imperative to develop pretreatment techniques for antibiotics in various matrices. In this paper, the pretreatment methods proposed in recent decades for antibiotics in coastal water, sediment, and biota are summarized, with emphasis on commonly used methods such as solid-phase extraction, solid-liquid extraction, matrix solid-phase dispersion, and QuEChERS. Additionally, the potential factors influencing the extraction performance and clean-up efficiency are analyzed. The advantages and disadvantages of the methods and their development are finally discussed.