Metabolomic analysis revealed that female mussel Mytilus galloprovincialis was sensitive to bisphenol A exposures
Ji, Chenglong1,2; Wei, Lei1,2; Zhao, Jianmin1; Wu, Huifeng1; Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
发表期刊ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
ISSN1382-6689
2014-03-01
卷号37期号:2页码:844-849
关键词Bisphenol a Mytilus Galloprovincialis Toxicological Effects Metabolomics
DOI10.1016/j.etap.2014.02.015
产权排序[Ji, Chenglong; Wei, Lei; Zhao, Jianmin; Wu, Huifeng] Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China; [Ji, Chenglong; Wei, Lei] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
作者部门中科院海岸带环境过程与生态修复重点实验室
英文摘要Bisphenol A (BPA) is a synthetic compound used in numerous chemicals, such as polycarbonate plastics and epoxy resins, and it can be released into aquatic environment and poses risk on aquatic organisms. In this work, metabolomics was applied to characterize the metabolic responses in mussel Mytilus galloprovincialis exposed to BPA. Our results indicated that the gonad of female mussel was sensitive to BPA exposures (1 and 10 mu g/L) for one month. However, no significant metabolic responses were observed in male mussel gonads exposed to these two concentrations of BPA. Overall, this limited study suggested that the gender differences should be considered in marine ecotoxicology. (C) 2014 Elsevier B.V. All rights reserved.; Bisphenol A (BPA) is a synthetic compound used in numerous chemicals, such as polycarbonate plastics and epoxy resins, and it can be released into aquatic environment and poses risk on aquatic organisms. In this work, metabolomics was applied to characterize the metabolic responses in mussel Mytilus galloprovincialis exposed to BPA. Our results indicated that the gonad of female mussel was sensitive to BPA exposures (1 and 10 mu g/L) for one month. However, no significant metabolic responses were observed in male mussel gonads exposed to these two concentrations of BPA. Overall, this limited study suggested that the gender differences should be considered in marine ecotoxicology. (C) 2014 Elsevier B.V. All rights reserved.
文章类型Article
资助机构Environmental Sciences & Ecology ; Pharmacology & Pharmacy ; Toxicology
收录类别SCI
语种英语
关键词[WOS]ENVIRONMENTALLY RELEVANT CONCENTRATIONS ; NMR-BASED METABOLOMICS ; RESPONSES ; HEALTH ; GILLS
研究领域[WOS]Environmental Sciences & Ecology ; Pharmacology & Pharmacy ; Toxicology
WOS记录号WOS:000335636600040
引用统计
被引频次:33[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/8767
专题中国科学院海岸带环境过程与生态修复重点实验室
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
通讯作者Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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Ji, Chenglong,Wei, Lei,Zhao, Jianmin,et al. Metabolomic analysis revealed that female mussel Mytilus galloprovincialis was sensitive to bisphenol A exposures[J]. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,2014,37(2):844-849.
APA Ji, Chenglong,Wei, Lei,Zhao, Jianmin,Wu, Huifeng,&Wu, HF .(2014).Metabolomic analysis revealed that female mussel Mytilus galloprovincialis was sensitive to bisphenol A exposures.ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,37(2),844-849.
MLA Ji, Chenglong,et al."Metabolomic analysis revealed that female mussel Mytilus galloprovincialis was sensitive to bisphenol A exposures".ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 37.2(2014):844-849.
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