Institutional Repository of Key Laboratory of Coastal Zone Environmental Processes, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences (KLCEP)
Metabolomic analysis revealed that female mussel Mytilus galloprovincialis was sensitive to bisphenol A exposures | |
Ji, Chenglong1,2; Wei, Lei1,2; Zhao, Jianmin1; Wu, Huifeng1; Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China. hfwu@yic.ac.cn | |
发表期刊 | ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY |
ISSN | 1382-6689 |
2014-03-01 | |
卷号 | 37期号:2页码:844-849 |
关键词 | Bisphenol a Mytilus Galloprovincialis Toxicological Effects Metabolomics |
DOI | 10.1016/j.etap.2014.02.015 |
产权排序 | [Ji, Chenglong; Wei, Lei; Zhao, Jianmin; Wu, Huifeng] Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China; [Ji, Chenglong; Wei, Lei] Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
作者部门 | 中科院海岸带环境过程与生态修复重点实验室 |
英文摘要 | Bisphenol A (BPA) is a synthetic compound used in numerous chemicals, such as polycarbonate plastics and epoxy resins, and it can be released into aquatic environment and poses risk on aquatic organisms. In this work, metabolomics was applied to characterize the metabolic responses in mussel Mytilus galloprovincialis exposed to BPA. Our results indicated that the gonad of female mussel was sensitive to BPA exposures (1 and 10 mu g/L) for one month. However, no significant metabolic responses were observed in male mussel gonads exposed to these two concentrations of BPA. Overall, this limited study suggested that the gender differences should be considered in marine ecotoxicology. (C) 2014 Elsevier B.V. All rights reserved.; Bisphenol A (BPA) is a synthetic compound used in numerous chemicals, such as polycarbonate plastics and epoxy resins, and it can be released into aquatic environment and poses risk on aquatic organisms. In this work, metabolomics was applied to characterize the metabolic responses in mussel Mytilus galloprovincialis exposed to BPA. Our results indicated that the gonad of female mussel was sensitive to BPA exposures (1 and 10 mu g/L) for one month. However, no significant metabolic responses were observed in male mussel gonads exposed to these two concentrations of BPA. Overall, this limited study suggested that the gender differences should be considered in marine ecotoxicology. (C) 2014 Elsevier B.V. All rights reserved. |
文章类型 | Article |
资助机构 | Environmental Sciences & Ecology ; Pharmacology & Pharmacy ; Toxicology |
收录类别 | SCI |
语种 | 英语 |
关键词[WOS] | ENVIRONMENTALLY RELEVANT CONCENTRATIONS ; NMR-BASED METABOLOMICS ; RESPONSES ; HEALTH ; GILLS |
研究领域[WOS] | Environmental Sciences & Ecology ; Pharmacology & Pharmacy ; Toxicology |
WOS记录号 | WOS:000335636600040 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.yic.ac.cn/handle/133337/8767 |
专题 | 中国科学院海岸带环境过程与生态修复重点实验室 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
通讯作者 | Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China. hfwu@yic.ac.cn |
作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc,YICCAS, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Ji, Chenglong,Wei, Lei,Zhao, Jianmin,et al. Metabolomic analysis revealed that female mussel Mytilus galloprovincialis was sensitive to bisphenol A exposures[J]. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,2014,37(2):844-849. |
APA | Ji, Chenglong,Wei, Lei,Zhao, Jianmin,Wu, Huifeng,&Wu, HF .(2014).Metabolomic analysis revealed that female mussel Mytilus galloprovincialis was sensitive to bisphenol A exposures.ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,37(2),844-849. |
MLA | Ji, Chenglong,et al."Metabolomic analysis revealed that female mussel Mytilus galloprovincialis was sensitive to bisphenol A exposures".ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 37.2(2014):844-849. |
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