Recent advances in molecular imprinting technology: current status, challenges and highlighted applications
Chen, Lingxin1; Xu, Shoufang1,2; Li, Jinhua1
2011
发表期刊CHEMICAL SOCIETY REVIEWS
ISSN0306-0012
卷号40期号:5页码:2922-2942
产权排序[Chen, Lingxin; Xu, Shoufang; Li, Jinhua] Chinese Acad Sci, Key Lab Coastal Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Xu, Shoufang] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
摘要Molecular imprinting technology (MIT) concerns formation of selective sites in a polymer matrix with the memory of a template. Recently, molecularly imprinted polymers (MIPs) have aroused extensive attention and been widely applied in many fields, such as solid-phase extraction, chemical sensors and artificial antibodies owing to their desired selectivity, physical robustness, thermal stability, as well as low cost and easy preparation. With the rapid development of MIT as a research hotspot, it faces a number of challenges, involving biological macromolecule imprinting, heterogeneous binding sites, template leakage, incompatibility with aqueous media, low binding capacity and slow mass transfer, which restricts its applications in various aspects. This critical review briefly reviews the current status of MIT, particular emphasis on significant progresses of novel imprinting methods, some challenges and effective strategies for MIT, and highlighted applications of MIPs. Finally, some significant attempts in further developing MIT are also proposed (236 references).; Molecular imprinting technology (MIT) concerns formation of selective sites in a polymer matrix with the memory of a template. Recently, molecularly imprinted polymers (MIPs) have aroused extensive attention and been widely applied in many fields, such as solid-phase extraction, chemical sensors and artificial antibodies owing to their desired selectivity, physical robustness, thermal stability, as well as low cost and easy preparation. With the rapid development of MIT as a research hotspot, it faces a number of challenges, involving biological macromolecule imprinting, heterogeneous binding sites, template leakage, incompatibility with aqueous media, low binding capacity and slow mass transfer, which restricts its applications in various aspects. This critical review briefly reviews the current status of MIT, particular emphasis on significant progresses of novel imprinting methods, some challenges and effective strategies for MIT, and highlighted applications of MIPs. Finally, some significant attempts in further developing MIT are also proposed (236 references).
通讯作者Chen, LX, Chinese Acad Sci, Key Lab Coastal Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China.lxchen@yic.ac.cn
关键词Solid-phase Extraction Performance Liquid-chromatography Restricted-access Materials Functionalized Silica-gel Beta-cyclodextrin Polymer Precipitation Polymerization Water Samples Ionic Liquid Selective Extraction Protein Recognition
作者部门环境化学实验室 
学科领域Chemistry, Multidisciplinary
项目资助者Chinese Academy of Sciences (IOCAS) [072715]; CAS/SAFEA
收录类别SCI
关键词[WOS]SOLID-PHASE EXTRACTION ; PERFORMANCE LIQUID-CHROMATOGRAPHY ; RESTRICTED-ACCESS MATERIALS ; FUNCTIONALIZED SILICA-GEL ; BETA-CYCLODEXTRIN POLYMER ; PRECIPITATION POLYMERIZATION ; WATER SAMPLES ; IONIC LIQUID ; SELECTIVE EXTRACTION ; PROTEIN RECOGNITION
文章类型Review
语种英语
WOS研究方向Chemistry
WOS记录号WOS:000289630700046
引用统计
被引频次:780[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/4853
专题中科院海岸带环境过程与生态修复重点实验室_环境化学实验室
中科院海岸带环境过程与生态修复重点实验室
作者单位1.Chinese Acad Sci, Key Lab Coastal Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Chen, Lingxin,Xu, Shoufang,Li, Jinhua. Recent advances in molecular imprinting technology: current status, challenges and highlighted applications[J]. CHEMICAL SOCIETY REVIEWS,2011,40(5):2922-2942.
APA Chen, Lingxin,Xu, Shoufang,&Li, Jinhua.(2011).Recent advances in molecular imprinting technology: current status, challenges and highlighted applications.CHEMICAL SOCIETY REVIEWS,40(5),2922-2942.
MLA Chen, Lingxin,et al."Recent advances in molecular imprinting technology: current status, challenges and highlighted applications".CHEMICAL SOCIETY REVIEWS 40.5(2011):2922-2942.
条目包含的文件 下载所有文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Recent advances in m(3676KB) 开放获取--浏览 下载
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Chen, Lingxin]的文章
[Xu, Shoufang]的文章
[Li, Jinhua]的文章
百度学术
百度学术中相似的文章
[Chen, Lingxin]的文章
[Xu, Shoufang]的文章
[Li, Jinhua]的文章
必应学术
必应学术中相似的文章
[Chen, Lingxin]的文章
[Xu, Shoufang]的文章
[Li, Jinhua]的文章
相关权益政策
暂无数据
收藏/分享
文件名: Recent advances in molecular imprinting technology current status, challenges and highlighted applications.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。