Aptamer-Nanoparticle-Based Optical Probes
Wang Guoqing; Chen Zhaopeng; Chen Lingxin
2010-03-01
Source PublicationPROGRESS IN CHEMISTRY
ISSN1005-281X
Volume22Issue:2-3Pages:489-499
Contribution Rank[Wang Guoqing; Chen Zhaopeng; Chen Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
AbstractAptamers are short single-stranded DNA (ssDNA) or RNA by in vitro screening of systematic evolution of ligands by exponential enrichment (SELEX). Based on their special structures which are easily rebuilt and modified, aptamers are of high affinity and specificity with a wide range of targets. These advantages have motivated aptamers to find broad applications for biomedicine, clinic diagnosis, drug discovery, environmental science and so on. Recently, aptamers integrated with nanotechnology have realized simple and rapid recognition of various targets with high sensitivity and selectivity owing to the novel optical, magnetic, electric, chemical and biological properties of nanomaterials. This paper reviews the latest advances and trends of aptamer-nanomaterial-based optical probes for biomolecules, metal ions and organic compounds, including colorimetry, fluoresence and surface-enhanced Raman spectroscopy (SERS).; Aptamers are short single-stranded DNA (ssDNA) or RNA by in vitro screening of systematic evolution of ligands by exponential enrichment (SELEX). Based on their special structures which are easily rebuilt and modified, aptamers are of high affinity and specificity with a wide range of targets. These advantages have motivated aptamers to find broad applications for biomedicine, clinic diagnosis, drug discovery, environmental science and so on. Recently, aptamers integrated with nanotechnology have realized simple and rapid recognition of various targets with high sensitivity and selectivity owing to the novel optical, magnetic, electric, chemical and biological properties of nanomaterials. This paper reviews the latest advances and trends of aptamer-nanomaterial-based optical probes for biomolecules, metal ions and organic compounds, including colorimetry, fluoresence and surface-enhanced Raman spectroscopy (SERS).
Corresponding AuthorChen, LX, Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
KeywordAptamer Nanoparticles Sensors Optical Probes
Department环境化学实验室 
Subject AreaChemistry, Multidisciplinary
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Indexed BySCI
WOS KeywordENHANCED RAMAN-SPECTROSCOPY ; FUNCTIONALIZED GOLD NANOPARTICLES ; FREE COLORIMETRIC DETECTION ; PROTEIN-DETECTION ; QUANTUM-DOT ; MICROFLUIDIC CHANNEL ; THROMBIN DETECTION ; AU NANOPARTICLES ; DNA APTAMER ; SENSOR
SubtypeArticle
Language英语
WOS Research AreaChemistry
WOS IDWOS:000275994000031
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.yic.ac.cn/handle/133337/3709
Collection中科院海岸带环境过程与生态修复重点实验室_环境化学实验室
AffiliationChinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
First Author AffilicationYantai Institute of Coastal Zone Research, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Wang Guoqing,Chen Zhaopeng,Chen Lingxin. Aptamer-Nanoparticle-Based Optical Probes[J]. PROGRESS IN CHEMISTRY,2010,22(2-3):489-499.
APA Wang Guoqing,Chen Zhaopeng,&Chen Lingxin.(2010).Aptamer-Nanoparticle-Based Optical Probes.PROGRESS IN CHEMISTRY,22(2-3),489-499.
MLA Wang Guoqing,et al."Aptamer-Nanoparticle-Based Optical Probes".PROGRESS IN CHEMISTRY 22.2-3(2010):489-499.
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