Aptamer-Nanoparticle-Based Optical Probes
Wang Guoqing; Chen Zhaopeng; Chen Lingxin
发表期刊PROGRESS IN CHEMISTRY
ISSN1005-281X
2010-03-01
卷号22期号:2-3页码:489-499
关键词Aptamer Nanoparticles Sensors Optical Probes
产权排序[Wang Guoqing; Chen Zhaopeng; Chen Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
通讯作者Chen, LX, Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
作者部门环境化学实验室 
英文摘要Aptamers are short single-stranded DNA (ssDNA) or RNA by in vitro screening of systematic evolution of ligands by exponential enrichment (SELEX). Based on their special structures which are easily rebuilt and modified, aptamers are of high affinity and specificity with a wide range of targets. These advantages have motivated aptamers to find broad applications for biomedicine, clinic diagnosis, drug discovery, environmental science and so on. Recently, aptamers integrated with nanotechnology have realized simple and rapid recognition of various targets with high sensitivity and selectivity owing to the novel optical, magnetic, electric, chemical and biological properties of nanomaterials. This paper reviews the latest advances and trends of aptamer-nanomaterial-based optical probes for biomolecules, metal ions and organic compounds, including colorimetry, fluoresence and surface-enhanced Raman spectroscopy (SERS).; Aptamers are short single-stranded DNA (ssDNA) or RNA by in vitro screening of systematic evolution of ligands by exponential enrichment (SELEX). Based on their special structures which are easily rebuilt and modified, aptamers are of high affinity and specificity with a wide range of targets. These advantages have motivated aptamers to find broad applications for biomedicine, clinic diagnosis, drug discovery, environmental science and so on. Recently, aptamers integrated with nanotechnology have realized simple and rapid recognition of various targets with high sensitivity and selectivity owing to the novel optical, magnetic, electric, chemical and biological properties of nanomaterials. This paper reviews the latest advances and trends of aptamer-nanomaterial-based optical probes for biomolecules, metal ions and organic compounds, including colorimetry, fluoresence and surface-enhanced Raman spectroscopy (SERS).
文章类型Article
收录类别SCI
语种英语
关键词[WOS]ENHANCED RAMAN-SPECTROSCOPY ; FUNCTIONALIZED GOLD NANOPARTICLES ; FREE COLORIMETRIC DETECTION ; PROTEIN-DETECTION ; QUANTUM-DOT ; MICROFLUIDIC CHANNEL ; THROMBIN DETECTION ; AU NANOPARTICLES ; DNA APTAMER ; SENSOR
研究领域[WOS]Chemistry
WOS记录号WOS:000275994000031
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/3709
专题中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心
作者单位Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
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Wang Guoqing,Chen Zhaopeng,Chen Lingxin. Aptamer-Nanoparticle-Based Optical Probes[J]. PROGRESS IN CHEMISTRY,2010,22(2-3):489-499.
APA Wang Guoqing,Chen Zhaopeng,&Chen Lingxin.(2010).Aptamer-Nanoparticle-Based Optical Probes.PROGRESS IN CHEMISTRY,22(2-3),489-499.
MLA Wang Guoqing,et al."Aptamer-Nanoparticle-Based Optical Probes".PROGRESS IN CHEMISTRY 22.2-3(2010):489-499.
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