Aptamer-Nanoparticle-Based Optical Probes | |
Wang Guoqing; Chen Zhaopeng; Chen Lingxin | |
发表期刊 | PROGRESS IN CHEMISTRY |
ISSN | 1005-281X |
2010-03-01 | |
卷号 | 22期号:2-3页码:489-499 |
关键词 | Aptamer Nanoparticles Sensors Optical Probes |
产权排序 | [Wang Guoqing; Chen Zhaopeng; Chen Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
通讯作者 | Chen, LX, Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
作者部门 | 环境化学实验室 |
英文摘要 | Aptamers are short single-stranded DNA (ssDNA) or RNA by in vitro screening of systematic evolution of ligands by exponential enrichment (SELEX). Based on their special structures which are easily rebuilt and modified, aptamers are of high affinity and specificity with a wide range of targets. These advantages have motivated aptamers to find broad applications for biomedicine, clinic diagnosis, drug discovery, environmental science and so on. Recently, aptamers integrated with nanotechnology have realized simple and rapid recognition of various targets with high sensitivity and selectivity owing to the novel optical, magnetic, electric, chemical and biological properties of nanomaterials. This paper reviews the latest advances and trends of aptamer-nanomaterial-based optical probes for biomolecules, metal ions and organic compounds, including colorimetry, fluoresence and surface-enhanced Raman spectroscopy (SERS).; Aptamers are short single-stranded DNA (ssDNA) or RNA by in vitro screening of systematic evolution of ligands by exponential enrichment (SELEX). Based on their special structures which are easily rebuilt and modified, aptamers are of high affinity and specificity with a wide range of targets. These advantages have motivated aptamers to find broad applications for biomedicine, clinic diagnosis, drug discovery, environmental science and so on. Recently, aptamers integrated with nanotechnology have realized simple and rapid recognition of various targets with high sensitivity and selectivity owing to the novel optical, magnetic, electric, chemical and biological properties of nanomaterials. This paper reviews the latest advances and trends of aptamer-nanomaterial-based optical probes for biomolecules, metal ions and organic compounds, including colorimetry, fluoresence and surface-enhanced Raman spectroscopy (SERS). |
文章类型 | Article |
收录类别 | SCI |
语种 | 英语 |
关键词[WOS] | ENHANCED RAMAN-SPECTROSCOPY ; FUNCTIONALIZED GOLD NANOPARTICLES ; FREE COLORIMETRIC DETECTION ; PROTEIN-DETECTION ; QUANTUM-DOT ; MICROFLUIDIC CHANNEL ; THROMBIN DETECTION ; AU NANOPARTICLES ; DNA APTAMER ; SENSOR |
研究领域[WOS] | Chemistry |
WOS记录号 | WOS:000275994000031 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.yic.ac.cn/handle/133337/3709 |
专题 | 中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心 |
作者单位 | Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
推荐引用方式 GB/T 7714 | Wang Guoqing,Chen Zhaopeng,Chen Lingxin. Aptamer-Nanoparticle-Based Optical Probes[J]. PROGRESS IN CHEMISTRY,2010,22(2-3):489-499. |
APA | Wang Guoqing,Chen Zhaopeng,&Chen Lingxin.(2010).Aptamer-Nanoparticle-Based Optical Probes.PROGRESS IN CHEMISTRY,22(2-3),489-499. |
MLA | Wang Guoqing,et al."Aptamer-Nanoparticle-Based Optical Probes".PROGRESS IN CHEMISTRY 22.2-3(2010):489-499. |
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