Quantitative assessment of in vivo distribution of nanoplastics in bivalve Ruditapes philippinarum using reliable SERS tag-labeled nanoplastic models

doi:10.1039/d2nr00157h

	Quantitative assessment of in vivo distribution of nanoplastics in bivalve Ruditapes philippinarum using reliable SERS tag-labeled nanoplastic models
	Du, Hongyu 1,2; Wang, Yunqing1,3,4 ; Zhang, Panpan 1,2; Mei, Rongchao 1; Ji, Yunxia 1; Zhao, Xizhen 1; Zhang, Zhiyang1,3 ; Ma, Jiping 5; Chen, Lingxin1,3,4,6
发表期刊	NANOSCALE
ISSN	2040-3364
	2022-06-01
卷号	14 期号:21 页码:7807-7816
DOI	10.1039/d2nr00157h
英文摘要	Nanoplastics (NPs) as emerging marine pollutants can be taken up by seafood organisms. It is crucial to quantitatively assess NP's distribution behavior in organisms to elucidate concentration dependent biological effects. Such a knowledge gap has remained due to the lack of reliable NP models and analytical methods. Herein, surface enhanced Raman scattering (SERS)-labeled NP models were developed and their bioavailability, distribution and accumulation in Ruditapes philippinarum, a typical marine bivalve, were quantitatively studied. Taking advantage of the sensitive and characteristic SERS signals of the NP models, distribution could be quickly and accurately obtained by the Raman imaging technique. Moreover, quantitative analysis of NPs could be performed by the detection of gold element contents via inductively coupled plasma mass spectroscopy (ICP-MS) detection. ICP-MS results revealed that after 3 days exposure of monodispersed NPs (100 nm, 0.2 mg L-1), the digestive gland accumulated 86.7% of whole-body NPs followed by gill (5.2%), mantle (5.1%), foot (1.3%), exhalant siphon (1.1%), and adductor (0.6%). Upon 11 days depuration, 98.7% of NPs in the digestive gland were excreted, whereas the clearance ratios in other organs were much lower. NP aggregates (around 1.5 mu m) demonstrated similar distribution and clearance trends to the monodispersed ones. However, the accumulation amount in each organ was 15.2% to 77.6% lower. Surface adherence and passive ingestion routes resulted in NP accumulation, which contributed to the comparable NP abundance in these organs. Additionally, boiling treatment (mimicking a cooking process) did not decrease the NP amount in these organs. This work provided a dual-mode and quantitative analysis protocol for NPs for the first time, and suggested the risk of NP uptake by humans via bivalve seafood diets.
收录类别	SCI
语种	英语
关键词[WOS]	MICROPLASTICS ; INGESTION ; MUSSEL ; IMPACTS
研究领域[WOS]	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS记录号	WOS:000797959900001
引用统计	被引频次：19[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/31072
专题	中国科学院海岸带环境过程与生态修复重点实验室中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心
通讯作者	Wang, Yunqing; Chen, Lingxin
作者单位	1.Chinese Acad Sci, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Shandong Key Lab Coastal Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China 4.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China 5.Qingdao Univ Technol, Sch Environm & Municipal Engn, Qingdao 266033, Peoples R China 6.Pilot Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China
推荐引用方式 GB/T 7714	Du, Hongyu,Wang, Yunqing,Zhang, Panpan,et al. Quantitative assessment of in vivo distribution of nanoplastics in bivalve Ruditapes philippinarum using reliable SERS tag-labeled nanoplastic models[J]. NANOSCALE,2022,14(21):7807-7816.
APA	Du, Hongyu.,Wang, Yunqing.,Zhang, Panpan.,Mei, Rongchao.,Ji, Yunxia.,...&Chen, Lingxin.(2022).Quantitative assessment of in vivo distribution of nanoplastics in bivalve Ruditapes philippinarum using reliable SERS tag-labeled nanoplastic models.NANOSCALE,14(21),7807-7816.
MLA	Du, Hongyu,et al."Quantitative assessment of in vivo distribution of nanoplastics in bivalve Ruditapes philippinarum using reliable SERS tag-labeled nanoplastic models".NANOSCALE 14.21(2022):7807-7816.