GWAS Reveal Novel Sex-Related Markers and Candidate Genes in Sea Urchin Mesocentrotus nudus

doi:10.1007/s10126-021-10084-x

	GWAS Reveal Novel Sex-Related Markers and Candidate Genes in Sea Urchin Mesocentrotus nudus
	Wang, Quanchao 1,3; Liu, Ying 1,2; Wang, Yanxia 1,2; Jiang, Shaoyu 1,2; Zhang, Chuanxin 1; Li, Baoquan1,3
发表期刊	MARINE BIOTECHNOLOGY
ISSN	1436-2228
	2021-11-23
页码	8
关键词	Mesocentrotus nudus Sex SNP markers Candidate genes
DOI	10.1007/s10126-021-10084-x
通讯作者	Li, Baoquan(bqli@yic.ac.cn)
英文摘要	Mesocentrotus nudus is an economically important mariculture species. Identification of sex-related markers and candidate genes has potential implications for sex-control breeding of Mesocentrotus nudus. The aim of this study was to identify the molecular markers and genes associated with the sex of M. nudus. Initial GWAS analysis based on 80 individuals genotyped by using GBS identified 22 sex-related SNPs located on 9 GBS tags. Further targeted sequencing in another population of 124 individuals confirmed that 7 SNPs located on 7 GBS tags displayed complete associations with sex, suggesting a ZW/ZZ sex-determination system in M. nudus. Besides, genome and transcriptome annotations presented that the heat shock protein 75 kDa, mitochondrial (trap1), and protein furry homolog-like (fryl) may be important candidate genes involved in sex determination and differentiation in M. nudus. However, further studies are needed to elucidate the functions of these genes. Overall, the current results not only provide molecular markers that may contribute to the sex-control breeding for M. nudus, but also provide new insights to understand the regulatory mechanism of sea urchin sex.
资助机构	Strategic Priority Research Program of the Chinese Academy of Sciences ; International Science Partnership Program of the Chinese Academy of Sciences ; Yantai Science and Technology Planning Project
收录类别	SCI
语种	英语
关键词[WOS]	GENOME-WIDE ASSOCIATION ; GONAD ; IDENTIFICATION ; LINKAGE ; TRAP1
研究领域[WOS]	Biotechnology & Applied Microbiology ; Marine & Freshwater Biology
WOS记录号	WOS:000721638500001
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/30924
专题	海岸带生物学与生物资源利用重点实验室海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
通讯作者	Li, Baoquan
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Wang, Quanchao,Liu, Ying,Wang, Yanxia,et al. GWAS Reveal Novel Sex-Related Markers and Candidate Genes in Sea Urchin Mesocentrotus nudus[J]. MARINE BIOTECHNOLOGY,2021:8.
APA	Wang, Quanchao,Liu, Ying,Wang, Yanxia,Jiang, Shaoyu,Zhang, Chuanxin,&Li, Baoquan.(2021).GWAS Reveal Novel Sex-Related Markers and Candidate Genes in Sea Urchin Mesocentrotus nudus.MARINE BIOTECHNOLOGY,8.
MLA	Wang, Quanchao,et al."GWAS Reveal Novel Sex-Related Markers and Candidate Genes in Sea Urchin Mesocentrotus nudus".MARINE BIOTECHNOLOGY (2021):8.