The gut microbiota and its products: Establishing causal relationships with obesity related outcomes | |
Li, Lili1,2; Zhang, Yubing1,3; Speakman, John Roger4; Hu, Shanliang5; Song, Yipeng5; Qin, Song1,2 | |
发表期刊 | OBESITY REVIEWS |
ISSN | 1467-7881 |
2021-09-06 | |
页码 | 14 |
关键词 | causality gut microbiota metabolites obesity |
DOI | 10.1111/obr.13341 |
通讯作者 | Song, Yipeng(syp1972@sina.com) ; Qin, Song(sqin@yic.ac.cn) |
英文摘要 | Gut microorganisms not only participate in the metabolism of carbohydrate, lipids, protein, and polypeptides in the intestine but also directly affect the metabolic phenotypes of the host. Although many studies have described the apparent effects of gut microbiota on human health, the development of metagenomics and culturomics in the past decade has generated a large amount of evidence suggesting a causal relationship between gut microbiota and obesity. The interaction between the gut microbiota and host is realized by microbial metabolites with multiple biological functions. We concentrated here on several representative beneficial species connected with obesity as well as the mechanisms, with particular emphasis on microbiota-dependent metabolites. Finally, we consider the potential clinical significance of these relationships to fuel the conception and realization of novel therapeutic and preventive strategies. |
资助机构 | Science and Technology Program of Yantai ; Youth Innovation Promotion Association of the Chinese Academy of Sciences |
收录类别 | SCI |
语种 | 英语 |
关键词[WOS] | VISCERAL FAT ACCUMULATION ; DIET-INDUCED OBESITY ; CHAIN AMINO-ACIDS ; LACTIS CECT 8145 ; BODY-MASS INDEX ; INSULIN-RESISTANCE ; BIFIDOBACTERIUM-ANIMALIS ; LACTOBACILLUS-REUTERI ; AKKERMANSIA-MUCINIPHILA ; INTESTINAL MICROBIOTA |
研究领域[WOS] | Endocrinology & Metabolism |
WOS记录号 | WOS:000693844400001 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.yic.ac.cn/handle/133337/29747 |
专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
通讯作者 | Song, Yipeng; Qin, Song |
作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Peoples R China 2.Yantai Univ, Coll Life Sci, Yantai, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao, Peoples R China 4.Chinese Acad Sci, Shenzhen Inst Adv Technol, Ctr Energy Metab & Reprod, Shenzhen Key Lab Metab Hlth, Shenzhen, Peoples R China 5.Yantai Yuhuangding Hosp, Dept Radiotherapy, Yantai, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Lili,Zhang, Yubing,Speakman, John Roger,et al. The gut microbiota and its products: Establishing causal relationships with obesity related outcomes[J]. OBESITY REVIEWS,2021:14. |
APA | Li, Lili,Zhang, Yubing,Speakman, John Roger,Hu, Shanliang,Song, Yipeng,&Qin, Song.(2021).The gut microbiota and its products: Establishing causal relationships with obesity related outcomes.OBESITY REVIEWS,14. |
MLA | Li, Lili,et al."The gut microbiota and its products: Establishing causal relationships with obesity related outcomes".OBESITY REVIEWS (2021):14. |
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文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
The gut microbiota a(1939KB) | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 |
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